RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
191 results for "alcohol use disorder" — page 9 of 10
R_2_01 — Human Brain Evolution and the Cognitive Revolution
The human brain tripled in size over 3 million years — from ~400 cm³ (Australopithecus) to ~1,400 cm³ (modern Homo sapiens). This is the most dramatic encephalization in the history of life, and NO consensus exists on wh
R_2_08 — Bipedalism — Why We Walk Upright and What It Cost Us
Bipedalism — habitual upright walking on two legs — is the defining characteristic of the hominin lineage, predating brain enlargement, tool use, and language by millions of years. The earliest evidence comes from Sahela
R_1_02 — The Cambrian Explosion
Between ~541 and ~520 million years ago, nearly ALL major animal body plans (phyla) appeared in the fossil record in an evolutionary "instant" — roughly 20 million years. Before this, life had been single-celled for ~3 b
S_4_01 — Existential Risk Taxonomy
Existential risk (x-risk) refers to any event that could permanently curtail humanity's long-term potential — including extinction, civilizational collapse without recovery, or irreversible loss of value (e.g., permanent
S_4_04 — Pandemic Risk — Ancient Plagues, Antibiotic Resistance, and Biosecurity
Pandemics have repeatedly reshaped human civilization, from the Plague of Justinian (541 CE, ~25-50 million dead, Yersinia pestis confirmed via ancient DNA) to the Black Death (1347-1353, killing 30-60% of Europe's popul
S_4_20 — Terraforming Technology
Terraforming — the hypothetical process of deliberately modifying a planet's atmosphere, temperature, surface topography, or ecology to make it habitable for Earth life — represents one of the most ambitious long-term en
S_3_01 — Climate Change, Civilization, and Deep-Time Context
Earth's climate has always changed — but the current rate and mechanism are unprecedented in geological history. This document places the modern climate crisis within the deep-time context that the corpus demands: from t
S_5_03 — 3D Printing and Additive Manufacturing
3D printing (additive manufacturing) builds objects layer by layer from digital models, reversing the subtractive logic of traditional manufacturing (cutting material away from a block). The technology originated with Ch
S_2_04 — Synthetic Biology — Engineering Life from First Principles
Synthetic biology represents the convergence of molecular biology, engineering, and computer science — applying rational design principles to living systems. The field was catalyzed by two landmark achievements: the cons
S_2_10 — Gene Drives: Ecosystem Engineering and Extinction Technology
Gene drives are genetic engineering systems that bias inheritance in sexually reproducing organisms, causing a modified gene to spread through a wild population at rates far exceeding normal Mendelian inheritance (which
S_2_01 — CRISPR and Human Genetic Engineering
CRISPR-Cas9 is the most transformative biotechnology discovery of the 21st century — a molecular tool that allows precise editing of DNA in any organism, including humans. Discovered in bacteria's immune system against v
S_2_03 — Bioethics of Human Enhancement
Should humans enhance themselves beyond the boundaries of nature? This is the central question of enhancement bioethics — a field at the intersection of philosophy, medicine, law, genetics, neuroscience, and disability s
F_1_02 — Cocaine and Nicotine in Egyptian Mummies — The Balabanova Controversy
In 1992, German toxicologist Svetlana Balabanova published findings of cocaine, nicotine, and hashish in Egyptian mummies held at the Munich Museum, igniting one of the most contentious debates in archaeology. Since coca
F_4_03 — Ancient Maritime Technology and Naval Knowledge
The history of maritime technology reveals that ancient civilizations achieved levels of nautical engineering and navigational skill far exceeding common assumptions. Phoenician sailors may have circumnavigated Africa ~6
F_4_14 — Ancient DNA and Migration Evidence
Ancient DNA (aDNA) analysis has transformed the study of human migration and cultural connections, providing direct genetic evidence for population movements that were previously inferred indirectly from archaeology, lin
F_3_16 — Ancient Astronomical Knowledge Transfer: East to West
The transfer of astronomical knowledge from East to West — from Mesopotamian/Babylonian, Egyptian, Indian, and Persian traditions through Greek, Hellenistic, and Islamic intermediaries to medieval and Renaissance Europe
F_3_22 — The Islamic Translation Movement: Bayt al-Hikma & the Preservation of Classical Knowledge
The Graeco-Arabic Translation Movement (c. 750–1000 CE) represents the most consequential program of systematic knowledge transfer in pre-modern history. Centered in Abbasid Baghdad but extending across the Islamic world
ZA_1_07 — EPR Paradox and Bell Tests: Quantum Nonlocality
The Einstein-Podolsky-Rosen (EPR) paradox, proposed in 1935, challenged quantum mechanics by arguing that entangled particles have definite properties prior to measurement — implying quantum mechanics is incomplete and s
I_2_09 — French GEIPAN: Europe's Official UAP Investigation
GEIPAN (Groupe d'Études et d'Informations sur les Phénomènes Aérospatiaux Non Identifiés) — housed within France's national space agency CNES (Centre National d'Études Spatiales) — is the world's only continuously operat
I_3_04 — Rendlesham Forest Incident (1980)
The Rendlesham Forest Incident (December 26–28, 1980) is the best-documented military UAP encounter in European history and one of the most investigated cases worldwide. Over two consecutive nights, United States Air For
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