RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
215 results for "ISO" — page 9 of 11
L_1_01 — Ancient DNA & Population Genetics
Modern paleogenomics has shown that human evolution was shaped by interbreeding, population structure, and repeated demographic turnover rather than a simple single-line progression. Ancient DNA revealed previously unkno
L_1_10 — Neanderthal Genome and Legacy in Modern Humans
The sequencing of the Neanderthal genome ranks among the most significant achievements in modern biology. Beginning with the draft genome of Green et al. (2010) and refined by later high-coverage genomes from the Altai,
L_1_04 — Archaic Human Species Synthesis
The human evolutionary tree is far more complex than the older linear model suggested. Fossils, ancient DNA, and proteomics now show that Homo sapiens overlapped with several other hominin lineages, including Neanderthal
L_1_12 — Ghost DNA: Unknown Archaic Hominin Admixture
"Ghost DNA" refers to genetic signals — segments of the genome, deviations in allele frequency distributions, or anomalous phylogenetic patterns — that indicate admixture (interbreeding) between anatomically modern human
L_4_04 — Ancient Proteomics and Paleoproteomics
Paleoproteomics — the recovery and analysis of ancient proteins from archaeological and paleontological specimens — has emerged as a revolutionary complement to ancient DNA (aDNA), dramatically extending the temporal and
L_4_17 — Transgenerational Epigenetic Trauma
Transgenerational epigenetic inheritance of trauma — the hypothesis that severe stress, famine, or psychological trauma experienced by one generation can alter the epigenetic marks (DNA methylation, histone modifications
L_4_01 — Ancient DNA from Sediment — Environmental DNA Revolution
Environmental DNA (eDNA) recovery from sediments has revolutionized our ability to detect the presence of organisms — including ancient humans — without requiring the discovery of any bones, teeth, or artifacts. The land
L_2_04 — Oceanian Genetics and Pacific Migration
The human settlement of Oceania represents the last major expansion of Homo sapiens across the globe, and the most remarkable feat of maritime exploration in human history. It occurred in two major phases separated by ~4
L_5_08 — Ancient DNA from Sediments: Cave Dirt Genomics
One of the most revolutionary methodological advances in ancient DNA (aDNA) research has been the recovery of hominin DNA directly from cave sediments — without any bones or teeth. This technique, pioneered by Matthias M
L_5_14 — Amino Acid Racemization Dating Method
Amino acid racemization (AAR) — a geochronological dating technique based on the chemical conversion of L-amino acids (the biologically predominant enantiomer in living organisms) to D-amino acids (the mirror-image confi
Y_4_12 — Psychosomatic Phenomena and the Placebo Effect
Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec
Y_4_11 — Trance States Across Cultures
Trance — an altered state of consciousness characterized by narrowed or shifted attention, altered sense of self, reduced awareness of external surroundings, and modified responsiveness — is one of the most universal fea
Y_5_18 — Sensory Deprivation & Float Tanks
Sensory deprivation — the systematic reduction or elimination of external sensory input — has been studied scientifically since the 1950s, with two primary paradigms: chamber REST (Restricted Environmental Stimulation Te
Y_5_22 — Brainwave Entrainment: Neural Oscillation, Binaural Beats, and Auditory Driving
Brainwave entrainment refers to the capacity of external rhythmic stimuli — auditory, visual, or electromagnetic — to synchronize endogenous neural oscillation patterns toward the frequency of the stimulus, a phenomenon
Y_2_06 — Dissociation, Depersonalization, and Derealization
Dissociation — the disruption of normally integrated functions of consciousness, memory, identity, emotion, perception, behavior, and sense of self — represents one of the most revealing natural experiments for understan
Y_2_09 — Sleep Paralysis, Hypnagogia, and Liminal States
Sleep paralysis — a temporary inability to move or speak while falling asleep or waking — is one of the most universal and culturally interpreted altered states, experienced by an estimated 7.6% of the general population
Y_3_18 — Sensory Deprivation and Float Tank Research
Sensory deprivation — the deliberate reduction of external sensory stimulation — and its modern therapeutic form, flotation-REST (Restricted Environmental Stimulation Technique), have been studied since the 1950s as a me
Y_1_09 — Toxins, Venoms, and Altered States
Several animal toxins and plant poisons produce dramatic altered states of consciousness, and their use in ritual, medicine, and folklore constitutes a significant chapter in the relationship between humans and psychoact
Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers
Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl
P_3_10 — Skepticism and Pyrrhonism
Skepticism — the philosophical position that knowledge is uncertain, limited, or impossible — is one of the oldest and most persistent currents in philosophy. Ancient Pyrrhonian skepticism (Pyrrho, ~360–270 BCE; Sextus E
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