RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,271 results for "ion channels" — page 87 of 164

Y_3_07 Credible Altered States

Y_3_07 — Music, Consciousness, and Altered States

Music is one of the most powerful modulators of conscious experience available without pharmacological intervention. Neuroimaging reveals that music engages an extraordinarily distributed network: auditory cortex (superi

music cognition music neuroscience chills frisson musical emotion default mode network music auditory cortex
Y_1_17 Verified Altered States

Y_1_17 — Ketamine Therapy and Dissociative Medicine

Ketamine — a dissociative anesthetic synthesized by Calvin Stevens at Parke-Davis in 1962 and first used clinically by Edward Domino and Guenter Corssen in 1966 — has emerged as a revolutionary treatment for treatment-re

ketamine esketamine spravato depression treatment-resistant nmda-receptor
Y_1_03 Credible Altered States

Y_1_03 — Classical Antiquity Entheogens Synthesis

This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The

entheogens psychedelics mystery religions Eleusinian Mysteries kykeon ergot
Y_1_05 Verified Altered States

Y_1_05 — Soma and Haoma — The Sacred Plant of Vedic and Avestan Ritual

Soma (Sanskrit: sóma) is the most celebrated sacred substance in the Vedic corpus — a pressed plant juice ritually offered to the gods and consumed by priests, praised in all 114 hymns of Rig Veda Mandala IX plus ~6 addi

Soma Haoma Rig Veda Mandala IX Avesta entheogen Amanita muscaria
Y_1_11 Verified Altered States

Y_1_11 — Ketamine: Dissociative Anesthetic and Consciousness Explorer

Ketamine is a dissociative anesthetic — first synthesized by Calvin Stevens in 1962 and introduced into clinical use by Edward Domino and Guenter Corssen (1966) — that has undergone a remarkable transformation from battl

ketamine dissociative anesthetic K-hole NMDA antagonist depression esketamine
Y_1_14 Credible Altered States

Y_1_14 — Toad Venom: Bufo alvarius, 5-MeO-DMT, and Desert Sacrament

Toad venom — specifically the venom of the Sonoran Desert toad (Incilius alvarius, formerly Bufo alvarius) — contains 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), one of the most potent psychoactive tryptamines known, p

5-MeO-DMT Bufo alvarius Incilius alvarius toad venom Sonoran Desert toad bufotenine
Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine
H_2_01 Verified Suppression & Thesis

H_2_01 — Key Findings and Reliability Assessment

This is the capstone analysis document for the entire research project. It provides the quantitative and qualitative answer to the core question: Is the evidence overwhelmingly positive regarding ancient serpent beings a

reliability findings thesis evidence tier consensus
H_2_13 Verified Suppression & Thesis

H_2_13 — Reproducibility in Archaeology: Method Reliability Assessment

Reproducibility — the ability of independent researchers to produce the same results using the same methods on the same or equivalent materials — is a cornerstone of scientific credibility. Yet archaeology faces unique c

reproducibility replication reliability method archaeology excavation
H_2_19 Speculative Suppression & Thesis

H_2_19 — Forbidden Archaeology — Cremo & Thompson Claims

Forbidden Archeology: The Hidden History of the Human Race (1993, revised edition 1998, 914 pages), authored by Michael A. Cremo and Richard L. Thompson, is the most comprehensive compendium of anomalous archaeological a

Forbidden Archaeology Michael Cremo Richard Thompson human antiquity anomalous artifacts knowledge filter
H_2_05 Verified Suppression & Thesis

H_2_05 — History Rewriting and Textbook Controversies

The rewriting of history through state-controlled textbooks and curricula is one of the most persistent and globally consequential forms of knowledge suppression. This document examines four major case studies: the "Lost

textbook controversies history rewriting usable past Lost Cause Confederate mythology Japan WWII textbooks
H_2_03 Verified Suppression & Thesis

H_2_03 — Academic Gatekeeping, Paradigm Resistance, and the Sociology of Knowledge

Academic gatekeeping — the processes by which scientific communities control which ideas, methods, and practitioners gain legitimacy — is simultaneously essential to quality (filtering out error, fraud, and pseudoscience

gatekeeping paradigm Kuhn paradigm shift peer review publish or perish
H_2_16 Credible Suppression & Thesis

H_2_16 — Dissident Scientists: Careers Destroyed by Heterodox Views

The history of science includes numerous cases of researchers whose careers were damaged, marginalized, or destroyed because they advanced ideas that contradicted the prevailing scientific paradigm — ideas that were, in

dissident heterodox heresy career suppression paradigm
H_2_15 Verified Suppression & Thesis

H_2_15 — Re-Dating Controversies: Sites Older Than Thought

The history of archaeology and prehistory is punctuated by re-dating controversies — cases where new evidence or improved dating technology revealed that sites, artifacts, or traditions were significantly older than prev

chronology re-dating radiocarbon luminescence older than thought Göbekli Tepe
H_2_14 Verified Suppression & Thesis

H_2_14 — Funding Bias in Science: Who Pays, Who Decides, What Gets Studied

Scientific research is shaped not only by curiosity and methodology but by who funds it — and funders' priorities, interests, and incentive structures systematically influence what questions get asked, what methods are u

funding bias research agenda corporate science grant system NIH NSF
H_2_06 Verified Suppression & Thesis

H_2_06 — Successful Paradigm Shifts in Archaeology: Cases Where Orthodoxy Was Wrong

The history of science contains well-documented cases where firmly held orthodoxies were overturned by new evidence, often after decades of resistance from established authorities. Thomas Kuhn's The Structure of Scientif

paradigm shift Thomas Kuhn Clovis First pre-Clovis Monte Verde Göbekli Tepe
H_1_17 Verified Suppression & Thesis

H_1_17 — COINTELPRO — FBI Domestic Surveillance

COINTELPRO (an acronym for COunter INTELligence PROgram) was a series of covert and illegal projects conducted by the United States Federal Bureau of Investigation (FBI) from 1956 to 1971, aimed at surveilling, infiltrat

COINTELPRO FBI J. Edgar Hoover domestic surveillance civil rights Black Panther
H_1_13 Verified Suppression & Thesis

H_1_13 — Knowledge Loss in the Fall of Rome and Early Middle Ages

The collapse of the Western Roman Empire (conventionally dated to 476 CE, though the decline was a process spanning the 3rd–6th centuries) produced one of the most dramatic and well-documented episodes of knowledge and t

fall of rome roman collapse dark ages early middle ages knowledge loss library destruction
H_1_05 Verified Suppression & Thesis

H_1_05 — Qin Shi Huang Book Burning and Burying of Scholars (213–212 BCE)

In 213 BCE, Qin Shi Huang — China's first emperor — ordered the burning of books (fenshu 焚書) that contradicted Legalist state ideology, and in 212 BCE reportedly buried alive 460 Confucian scholars (kengru 坑儒) who defied

Qin Shi Huang book burning burying of scholars fenshu kengru Legalism Li Si
H_1_10 Verified Suppression & Thesis

H_1_10 — Damnatio Memoriae and State-Directed Historical Erasure

Damnatio memoriae ("condemnation of memory") — the deliberate, systematic erasure of an individual, event, or idea from the historical record by a governing authority — is one of the oldest and most persistent forms of i

damnatio memoriae memory erasure unperson Soviet retouching photo manipulation Cultural Revolution