RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
3,692 results for "G protein" — page 83 of 185
Y_5_15 — Altitude Sickness and High-Altitude Consciousness: Mountain Visions
Altitude sickness — a spectrum of syndromes caused by hypobaric hypoxia (reduced oxygen partial pressure at elevation) — produces some of the most dramatic and well-documented involuntary altered states of consciousness
Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks
MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w
Y_2_07 — Temporal Lobe Epilepsy and Religious Experience
Temporal lobe epilepsy (TLE) — seizures originating in the temporal lobes, which contain structures critical for memory (hippocampus), emotion (amygdala), and sensory-experiential processing — produces some of the most d
Y_2_10 — Drowning and Near-Drowning: Aquatic Altered Consciousness
Drowning — defined by the WHO (2002, revised 2005) as "the process of experiencing respiratory impairment from submersion/immersion in liquid" — is one of the leading causes of accidental death worldwide (~236,000 deaths
Y_3_01 — Kundalini and Serpent Energy Traditions
Kundalini ("coiled one" in Sanskrit) describes a dormant serpent-like energy said to reside at the base of the spine, which, when "awakened" through meditation, breathwork, or spontaneous experience, rises through a cent
Y_3_14 — Chanting and Repetitive Vocalization: Sonic Pathways to Trance
Chanting and repetitive vocalization — the sustained production of rhythmic, patterned vocal sounds — is arguably the most ancient and universal method of inducing altered states of consciousness through acoustic means.
Y_3_15 — Pilgrimage as Altered State: Walking, Devotion, and Transformation
Pilgrimage — the deliberate journey to a sacred place as an act of devotion, penance, healing, or spiritual seeking — is one of humanity's most ancient and universal practices for inducing transformative altered states t
Y_3_10 — Fasting, Asceticism, and Altered Consciousness
Fasting and ascetic practices — deliberate deprivation of food, sleep, comfort, or sensory input — have been used across virtually all religious and spiritual traditions to induce altered states of consciousness, visions
Y_3_20 — Enlightenment Neuroscience: Satori, Samadhi & Mystical States
Enlightenment — known as satori or kensho in Zen Buddhism, samadhi in Hindu yogic traditions, fana in Sufism, theosis in Eastern Orthodox Christianity, and unio mystica in the Western mystical tradition — refers to state
Y_3_17 — Breathwork Traditions: Pranayama, Holotropic Breathing, and Respiratory Consciousness
Breathwork — the intentional manipulation of breathing patterns to influence physiological, psychological, and (in traditional frameworks) spiritual states — encompasses ancient practices dating to the earliest recorded
Y_1_03 — Classical Antiquity Entheogens Synthesis
This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The
Y_1_02 — Ergot, Sacred Pharmacology, and History
This document examines Ergot, Sacred Pharmacology, and History, a topic within the Consciousness research area. Key areas of investigation include Claviceps purpurea — Biology and Chemistry, Ergot Alkaloids — The Chemist
Y_1_13 — Xenon Gas and Nitrous Oxide: Anesthetic Gases as Consciousness Probes
Nitrous oxide (N₂O — "laughing gas") and xenon (Xe — a noble gas) are two anesthetic gases that have served as remarkable probes of consciousness — revealing how the manipulation of a single molecule or atom can dissolve
Y_1_19 — Ibogaine Reset Mechanism
Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog
Y_1_08 — Cannabis: History, Ethnobotany, and Pharmacology
Cannabis (Cannabis sativa L.) is one of humanity's oldest cultivated plants, with a relationship spanning at least 12,000 years based on archaeological evidence. Its use as fiber (hemp), food (seeds), medicine, and psych
Y_1_15 — Micro-Dosing: Sub-Perceptual Psychedelic Use and Cognitive Effects
Micro-dosing — the practice of regularly consuming sub-perceptual doses (typically 1/10th to 1/20th of a standard recreational dose) of psychedelic substances, most commonly LSD (~10–20 micrograms) or psilocybin (~0.1–0.
Y_1_07 — Ego Dissolution and Psychedelic Neuroscience
Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p
Y_1_16 — Psychedelic Legal Frameworks: Regulation, Decriminalization, and Therapeutic Access
The legal status of psychedelic substances — including psilocybin, LSD, MDMA, DMT/ayahuasca, mescaline, and ibogaine — has undergone dramatic shifts since the mid-20th century, moving from unregulated research compounds
H_2_09 — The Galileo Affair — Science, Religion, and Power
The Galileo affair — the Roman Inquisition's condemnation of Galileo Galilei (1564–1642) for defending the Copernican heliocentric model — is the archetypal case of religious authority suppressing scientific knowledge, i
H_2_10 — Archaeological Nationalism: Weaponizing the Past
Archaeological nationalism is the systematic appropriation of archaeological evidence, historical narratives, and cultural heritage to serve nationalist political agendas — constructing, validating, or legitimizing claim
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