RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,692 results for "G protein" — page 82 of 185

L_5_07 Verified Genetics & Origins

L_5_07 — Genetics of Speech and Language: Beyond FOXP2

Language is humanity's most distinctive cognitive ability — and identifying its genetic basis has been a central goal of human genetics and neuroscience since the discovery of the KE family and the FOXP2 gene. The KE fam

FOXP2 language genetics speech CNTNAP2 SRPX2 ATP2C2
L_5_11 Verified Genetics & Origins

L_5_11 — Genetics of Altitude Adaptation: Tibet, Andes, Ethiopia

High-altitude adaptation represents one of the most dramatic and best-studied examples of natural selection in contemporary human populations. More than 140 million people worldwide live at elevations above 2,500 meters,

altitude adaptation hypoxia EPAS1 EGLN1 HIF pathway hemoglobin
L_5_13 Credible Genetics & Origins

L_5_13 — The Microbiome-Brain Axis: Gut Bacteria, Mood & Consciousness

The microbiome-gut-brain axis — bidirectional communication between the trillions of gut microorganisms and the central nervous system — has emerged as one of the most significant frontiers in neuroscience and consciousn

microbiome-brain-axis gut-brain-axis psychobiome vagus-nerve microbial-metabolites serotonin-gut
Y_4_02 Verified Altered States

Y_4_02 — Savant Syndrome and Acquired Genius

Savant syndrome — extraordinary ability coexisting with significant cognitive disability — affects roughly 1 in 10 people with autism and ~1 in 2,000 people with other developmental disabilities or brain injuries. What m

savant syndrome acquired savant traumatic brain injury autistic savant Kim Peek Daniel Tammet
Y_4_14 Verified Altered States

Y_4_14 — Virtual Reality, Immersive Technology, and Altered Perception

Virtual reality (VR) and immersive technologies create genuine altered states of perception — not merely visual illusions but deep modifications of body ownership, spatial awareness, self-identity, and emotional processi

virtual reality VR augmented reality AR embodiment rubber hand illusion
Y_4_15 Credible Altered States

Y_4_15 — Sensory Overload and Information Flooding: Excess as Altered State

Sensory overload — the state that arises when sensory input exceeds the brain's capacity for orderly processing — represents the mirror image of sensory deprivation as a pathway to altered consciousness. While deprivatio

sensory overload information overload Ganzfeld rave culture overwhelm information flooding
Y_4_16 Verified Altered States

Y_4_16 — Hypnagogia: The Threshold State Between Waking and Sleep

Hypnagogia is the transitional state of consciousness experienced during the onset of sleep (waking-to-sleep), characterized by vivid spontaneous imagery, auditory hallucinations, distorted body perception, and loosened

hypnagogia hypnagogic hypnopompic sleep onset threshold consciousness tetris effect
Y_4_18 Verified Altered States

Y_4_18 — Sleep Disorders and Parasomnias: Pathologies of Consciousness in Sleep

Sleep disorders affect an estimated 50–70 million Americans and ~1 billion people globally, causing significant morbidity, mortality, and economic burden. The field was transformed by the discovery of distinct sleep stag

sleep-disorders parasomnia insomnia narcolepsy sleep-apnea rem-behavior-disorder
Y_4_20 Credible Altered States

Y_4_20 — Drumming & Trance Neuroscience

Shamanic drumming — typically monotonous percussive rhythms at approximately 4–4.5 beats per second — has been used across virtually every indigenous culture as a primary technology for inducing trance states, and modern

drumming trance theta rhythm auditory driving EEG entrainment
Y_4_13 Verified Altered States

Y_4_13 — Collective Effervescence and Group Altered States

Collective effervescence — Émile Durkheim's term (The Elementary Forms of Religious Life, 1912) for the heightened emotional energy generated when people gather and act together in coordinated ritual — describes a group

collective effervescence Durkheim group ritual emotional contagion synchrony entrainment
Y_4_10 Verified Altered States

Y_4_10 — Glossolalia, Xenoglossy, and Altered Language States

Glossolalia — commonly known as "speaking in tongues" — is a cross-cultural phenomenon in which individuals produce fluent, seemingly language-like vocalizations that do not correspond to any known natural language. Prac

glossolalia speaking in tongues xenoglossy Pentecostal Pythia Delphi
Y_4_05 Verified Altered States

Y_4_05 — Dreams, Dream Incubation, and Oneiric Knowledge

Dreams have been treated as a source of knowledge, prophecy, and divine communication in virtually every civilization. Ancient Mesopotamians maintained professional dream interpreters (šāʾilu) and compiled dream omen com

dream dreaming dream incubation oneiric Asklepion temple sleep
Y_4_21 Credible Altered States

Y_4_21 — Fasting-Induced Altered States

Fasting-induced altered states of consciousness — visionary experiences, euphoria, time distortion, dissociation, and mystical-type experiences produced by prolonged food deprivation — represent one of humanity's oldest

fasting altered states ketosis beta-hydroxybutyrate vision quest asceticism
Y_5_16 Credible Altered States

Y_5_16 — Breathwork Traditions: Pranayama, Holotropic, Tummo & Physiological Mechanisms

Deliberate manipulation of breathing patterns — breathwork — represents one of humanity's oldest and most cross-culturally widespread technologies for inducing altered states of consciousness, modulating autonomic functi

breathwork pranayama holotropic-breathing tummo hyperventilation respiratory-alkalosis
Y_5_09 Credible Altered States

Y_5_09 — Firewalking: Altered States, Pain Override, and Ritual Confidence

Firewalking — the practice of walking barefoot over a bed of hot embers, coals, or heated stones — is one of the most dramatic and visually arresting ritual practices in world culture, documented across diverse tradition

firewalking fire ritual Anastenaria pain override Leidenfrost effect endorphins
Y_5_13 Verified Altered States

Y_5_13 — Starvation and Dehydration: Cognitive Effects of Deprivation States

Starvation and dehydration — states of severe and prolonged nutritional and fluid deprivation — produce a characteristic and well-documented progression of cognitive, perceptual, and emotional alterations that constitute

starvation dehydration Minnesota starvation experiment cognitive impairment hallucination survival psychology
Y_5_08 Credible Altered States

Y_5_08 — Sweat Lodge and Heat-Induced Altered States

The sweat lodge — and heat-induced altered states more broadly — represents one of the most ancient and geographically widespread methods of intentionally altering consciousness through controlled hyperthermia: sustained

sweat lodge inipi Lakota sauna banya heat therapy
Y_5_10 Credible Altered States

Y_5_10 — Extreme Fasting: Breatharian Claims, Autophagy, and Metabolic States

Extreme fasting — prolonged and severe caloric restriction or complete food abstinence — occupies a unique position at the intersection of contemplative/ascetic practice, metabolic science, and pseudoscientific extremism

fasting autophagy caloric restriction breatharianism inedia metabolic states
Y_5_12 Speculative Altered States

Y_5_12 — Dark Retreat: Extended Light Deprivation and Endogenous Visionary States

The dark retreat (yangti nagpo or mun mtshams in Tibetan) is an advanced contemplative practice — primarily within the Dzogchen (Great Perfection) tradition of Tibetan Buddhism and the closely related Bön tradition — in

dark retreat yangti Tibetan Buddhism melatonin DMT hypothesis light deprivation
Y_5_07 Verified Altered States

Y_5_07 — Phenomenology of Pain and Pain Modulation

Pain — defined by the International Association for the Study of Pain (IASP, revised 2020) as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissu

pain nociception pain modulation gate control theory Melzack Wall