RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 documents 34 sections 43,623 citations 34,854 keywords indexed 4 evidence tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

2,532 results for "CI" — page 81 of 127

L_2_07 Genetics & Origins

L_2_07 — European Genetics and Three Ancestral Populations

The genetic history of Europe has been revolutionized by ancient DNA, revealing that most present-day Europeans can be modeled at a broad level as mixtures of three major ancestral components assembled over the past ~10,

European genetics ancient DNA three ancestral populations Western Hunter-Gatherers Early European Farmers Steppe pastoralists
L_2_01 Genetics & Origins

L_2_01 — Domestication Genetics — How Humans Reshaped Life

Domestication — the genetic transformation of wild species into human-dependent organisms — ranks among the most consequential biological processes in Earth's history.

domestication dog origin wheat genetics maize teosinte Belyaev fox experiment domestication syndrome
L_2_10 Verified Genetics & Origins

L_2_10 — Human–Dog Co-Evolution: 40,000 Years Together

The domestication of the dog (Canis lupus familiaris) from gray wolves (Canis lupus) represents the oldest known domestication event and one of the most consequential interspecies relationships in human history — predati

dog domestication wolf Canis lupus familiaris co-evolution Larson Frantz
L_2_05 Genetics & Origins

L_2_05 — Americas Peopling Genetics

The peopling of the Americas is one of the clearest cases where ancient DNA and archaeology have converged to overturn an older narrative. The core model now favored by genetics is that the main ancestry of Indigenous Am

Americas peopling Beringia Clovis pre-Clovis Native American genetics mtDNA haplogroups
L_2_13 Verified Genetics & Origins

L_2_13 — Genetic History of Island Southeast Asia: Wallace Line and Beyond

Island Southeast Asia (ISEA) — the vast archipelagic region encompassing the Philippines, Indonesia, Timor, and the islands between mainland Asia and Australo-Papua — is one of the most genetically complex regions on Ear

Island Southeast Asia ISEA Wallace Line Wallacea Sunda Sahul
L_2_18 Verified Genetics & Origins

L_2_18 — Archaic Admixture in Africa (Ghost Populations)

While Neanderthal and Denisovan admixture in non-African populations has been well-documented since Svante Pääbo's landmark 2010 Neanderthal genome paper, evidence for archaic admixture within Africa represents a more re

archaic admixture ghost population African genetics ancient DNA introgression archaic hominin
L_3_06 Genetics & Origins

L_3_06 — Genetics of Intelligence and Cognition

The genetics of intelligence — one of the most studied yet contentious areas in behavioral genetics — has established that cognitive ability, as measured by standardized tests, has a substantial heritable component (~50–

intelligence genetics cognitive ability IQ heritability GWAS intelligence polygenic score educational attainment
L_3_09 Verified Genetics & Origins

L_3_09 — HLA Diversity and Immune System Evolution

The Human Leukocyte Antigen (HLA) system — the human version of the Major Histocompatibility Complex (MHC) found in all jawed vertebrates — is the most polymorphic gene region in the entire human genome. Located on chrom

HLA MHC major histocompatibility complex immune diversity balancing selection antigen presentation
L_3_04 Genetics & Origins

L_3_04 — Y-Chromosome Phylogeny and Patrilineal Deep History

The Y chromosome, transmitted exclusively from father to son, provides a uniquely informative window into patrilineal human history.

Y-chromosome haplogroup patrilineal Y-chromosomal Adam A00 R1b
L_3_13 Verified Genetics & Origins

L_3_13 — Human Accelerated Regions: What Makes Us Genetically Unique

Human Accelerated Regions (HARs) are short segments of the genome that were highly conserved across millions of years of mammalian evolution — indicating strong functional constraint — but then underwent a burst of rapid

human accelerated regions HARs HAR1 HACNS1 conserved noncoding enhancer
L_3_12 Verified Genetics & Origins

L_3_12 — Genetics of Pigmentation: Skin, Hair, and Eye Color Evolution

Human pigmentation — the variation in skin, hair, and eye color across populations — is one of the most visible and best-understood examples of natural selection in our species. Pigmentation is determined primarily by th

pigmentation melanin skin color SLC24A5 SLC45A2 MC1R
L_3_03 Genetics & Origins

L_3_03 — Lactase Persistence and Gene-Culture Coevolution

Lactase persistence — the ability of adults to digest the milk sugar lactose — is the most thoroughly documented case of gene-culture coevolution in the human species. The ancestral mammalian condition is lactase non-per

lactase persistence lactose intolerance LCT gene gene-culture coevolution pastoralism dairy farming
L_3_08 Genetics & Origins

L_3_08 — Genetics of Skin, Hair, and Eye Color

Human pigmentation — skin, hair, and eye color — is one of the best-understood complex traits in human genetics, with a relatively modest number of genes explaining a large proportion of variation compared to most polyge

pigmentation genetics melanin eumelanin pheomelanin MC1R OCA2
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
L_5_12 Credible Genetics & Origins

L_5_12 — Microbiome-Consciousness Connection: Gut-Brain Axis and Microbial Influence on Mind

The microbiome-gut-brain axis — the bidirectional communication network linking the ~38 trillion microorganisms inhabiting the human gastrointestinal tract with the central nervous system — has emerged as one of the most

microbiome gut-brain axis psychobiotics vagus nerve serotonin Cryan
L_5_13 Credible Genetics & Origins

L_5_13 — The Microbiome-Brain Axis: Gut Bacteria, Mood & Consciousness

The microbiome-gut-brain axis — bidirectional communication between the trillions of gut microorganisms and the central nervous system — has emerged as one of the most significant frontiers in neuroscience and consciousn

microbiome-brain-axis gut-brain-axis psychobiome vagus-nerve microbial-metabolites serotonin-gut
Y_5_16 Credible Altered States

Y_5_16 — Breathwork Traditions: Pranayama, Holotropic, Tummo & Physiological Mechanisms

Deliberate manipulation of breathing patterns — breathwork — represents one of humanity's oldest and most cross-culturally widespread technologies for inducing altered states of consciousness, modulating autonomic functi

breathwork pranayama holotropic-breathing tummo hyperventilation respiratory-alkalosis
Y_5_09 Credible Altered States

Y_5_09 — Firewalking: Altered States, Pain Override, and Ritual Confidence

Firewalking — the practice of walking barefoot over a bed of hot embers, coals, or heated stones — is one of the most dramatic and visually arresting ritual practices in world culture, documented across diverse tradition

firewalking fire ritual Anastenaria pain override Leidenfrost effect endorphins
Y_5_13 Verified Altered States

Y_5_13 — Starvation and Dehydration: Cognitive Effects of Deprivation States

Starvation and dehydration — states of severe and prolonged nutritional and fluid deprivation — produce a characteristic and well-documented progression of cognitive, perceptual, and emotional alterations that constitute

starvation dehydration Minnesota starvation experiment cognitive impairment hallucination survival psychology
Y_5_20 Verified Altered States

Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks

MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w

MDMA ecstasy entactogen empathogen serotonin PTSD therapy