RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
556 results for "old friends hypothesis" — page 8 of 28
ZF_1_03 — Seafloor Spreading, Plate Tectonics and Marine Geology
The discovery that the ocean floor is not ancient and static but young, dynamic, and continuously recycled revolutionized Earth science in the 20th century. Seafloor spreading — proposed by Harry Hess (1962) and confirme
Z_3_02 — Epigenetic Inheritance & Transgenerational Effects
Epigenetic inheritance refers to the transmission of phenotypic information across generations through mechanisms other than changes in DNA sequence. The three primary molecular mechanisms — DNA methylation, histone modi
Z_2_12 — Genetics of Pain Perception
Pain perception — the subjective experience triggered by actual or potential tissue damage — varies enormously across individuals, with genetic factors accounting for 25–50% of the variance in pain sensitivity (twin stud
Z_2_09 — Mitochondrial Genetics and Diseases
Human mitochondrial DNA (mtDNA) is a 16,569-bp circular genome encoding 37 genes: 13 proteins (all subunits of the oxidative phosphorylation/OXPHOS complexes I, III, IV, and V), 22 transfer RNAs, and 2 ribosomal RNAs. Un
Z_1_05 — Genomic Imprinting and Parent-of-Origin Effects
Genomic imprinting is an epigenetic phenomenon in which a gene's expression depends on whether it was inherited from the mother or the father — violating the standard Mendelian assumption that both parental copies functi
Z_1_12 — Genome Architecture and 3D Organization
The human genome — approximately 6.4 billion base pairs of DNA — is packed into a nucleus only ~6 μm in diameter. If stretched end-to-end, the DNA of a single human cell would extend about 2 meters, yet it is packaged an
Z_1_11 — Polyploidy and Genome Duplication
Polyploidy — the possession of more than two complete sets of chromosomes — is a major force in genome evolution, particularly in plants and some animal lineages. Susumu Ohno (1970) proposed that whole genome duplication
Z_4_16 — Phase Separation in Cell Biology: Membraneless Organelles and Biomolecular Condensates
Liquid-liquid phase separation (LLPS) is the biophysical process by which proteins and nucleic acids demix from the surrounding cytoplasm or nucleoplasm to form concentrated, membrane-free droplets called biomolecular co
Z_4_03 — Forensic Genetics and DNA Identification
Forensic genetics uses DNA analysis to identify individuals, establish biological relationships, and solve criminal cases — a revolution that began when Sir Alec Jeffreys (1984, University of Leicester) discovered DNA fi
K_3_05 — Extended Mind and Cognitive Extension
The extended mind thesis (EMT), proposed by Andy Clark and David Chalmers in their landmark 1998 paper "The Extended Mind," argues that cognitive processes need not be confined within the skull — external objects, tools,
K_3_04 — Anesthesia and Consciousness
General anesthesia — the reversible, drug-induced abolition of consciousness — is one of medicine's greatest achievements and, paradoxically, one of its least understood. Approximately 350 million surgical procedures per
K_4_17 — Plant and Fungal Consciousness: Intelligence without Neurons
The question of whether plants and fungi possess forms of consciousness, intelligence, or cognition has moved from philosophical speculation to active scientific investigation. Plants exhibit sophisticated information pr
K_4_07 — Biofield Science — Electromagnetic and Subtle Energy Research
Biofield science investigates the electromagnetic, acoustic, and hypothesized "subtle energy" fields associated with living organisms, spanning a spectrum from rigorous biophysics to highly contested alternative medicine
K_4_09 — Consciousness, Virtual Reality, and Simulated Environments
Virtual reality (VR) has become one of the most powerful tools for investigating the construction of conscious experience — particularly body ownership, self-location, embodiment, spatial presence, and the boundaries of
K_5_07 — Psychophysics: Measuring the Relationship Between Mind and World
Psychophysics — literally "the physics of the soul/mind" — is the scientific study of the quantitative relationship between physical stimuli and the sensations and perceptions they produce. Founded by Gustav Theodor Fech
E_3_05 — Megafauna Extinction — Overkill, Climate, or Cosmic Impact?
The late Quaternary megafauna extinction represents one of the most dramatic biodiversity losses in the last 66 million years, eliminating approximately 178 species of large-bodied mammals (≥44 kg) across six continents
E_2_07 — The 4.2 Kiloyear Event — Bronze Age Climate Catastrophe
The 4.2 kiloyear event (~2200 BCE) was a severe, century-scale aridification episode that constitutes one of the most significant abrupt climate changes of the Holocene. Identified through speleothem, marine sediment, an
E_2_02 — Toba Supervolcano and the 74,000 BP Genetic Bottleneck
Approximately 74,000 years ago, the Toba supervolcano on the island of Sumatra (modern Indonesia) produced the largest volcanic eruption in the last 2 million years: a VEI-8 (Volcanic Explosivity Index maximum) event tha
E_4_26 — Younger Dryas Impact Evidence: A Comprehensive Review
The Younger Dryas Impact Hypothesis (YDIH) proposes that one or more extraterrestrial objects (comet or asteroid fragments) struck or exploded over the Earth approximately 12,900 years ago (12.9 ka BP), triggering the Yo
E_4_08 — The 3102/3114 BCE Epoch Date Parallel
This document examines The 3102/3114 BCE Epoch Date Parallel, a topic within the Cataclysms and Chronology research area. Key areas of investigation include The Hindu Kali Yuga — February 17/18, 3102 BCE, The Maya Long C
BROWSE BY SECTION — 3,721 documents across 34 fields