RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

396 results for "genome evolution" — page 8 of 20

L_3_13 Verified Genetics & Origins

L_3_13 — Human Accelerated Regions: What Makes Us Genetically Unique

Human Accelerated Regions (HARs) are short segments of the genome that were highly conserved across millions of years of mammalian evolution — indicating strong functional constraint — but then underwent a burst of rapid

human accelerated regions HARs HAR1 HACNS1 conserved noncoding enhancer
L_3_05 Verified Genetics & Origins

L_3_05 — Blood Type Genetics and the ABO System

Blood group genetics represents one of the earliest and most clinically important applications of Mendelian inheritance in human biology. Karl Landsteiner's discovery of the ABO blood group system (1900–1901) — which ear

blood type ABO system Rh factor Karl Landsteiner blood transfusion blood group antigens
L_3_10 Verified Genetics & Origins

L_3_10 — Telomeres Aging and Longevity Genetics

Telomeres — the repetitive DNA sequences (TTAGGG in vertebrates) capping the ends of linear chromosomes — protect genome integrity by preventing chromosome ends from being recognized as double-strand breaks and triggerin

telomere telomerase aging senescence Hayflick limit shelterin
L_3_11 Verified Genetics & Origins

L_3_11 — Genetics of Taste and Dietary Adaptation

Taste perception — the ability to detect sweet, salty, sour, bitter, and umami (savory) stimuli — is mediated by genetically encoded receptor proteins whose variation across individuals and populations reflects evolution

taste genetics TAS2R_4_05 PTC PROP bitter taste umami
L_3_08 Verified Genetics & Origins

L_3_08 — Genetics of Skin, Hair, and Eye Color

Human pigmentation — skin, hair, and eye color — is one of the best-understood complex traits in human genetics, with a relatively modest number of genes explaining a large proportion of variation compared to most polyge

pigmentation genetics melanin eumelanin pheomelanin MC1R OCA2
L_5_11 Verified Genetics & Origins

L_5_11 — Genetics of Altitude Adaptation: Tibet, Andes, Ethiopia

High-altitude adaptation represents one of the most dramatic and best-studied examples of natural selection in contemporary human populations. More than 140 million people worldwide live at elevations above 2,500 meters,

altitude adaptation hypoxia EPAS1 EGLN1 HIF pathway hemoglobin
Y_3_07 Credible Altered States

Y_3_07 — Music, Consciousness, and Altered States

Music is one of the most powerful modulators of conscious experience available without pharmacological intervention. Neuroimaging reveals that music engages an extraordinarily distributed network: auditory cortex (superi

music cognition music neuroscience chills frisson musical emotion default mode network music auditory cortex
H_2_09 Verified Suppression & Thesis

H_2_09 — The Galileo Affair — Science, Religion, and Power

The Galileo affair — the Roman Inquisition's condemnation of Galileo Galilei (1564–1642) for defending the Copernican heliocentric model — is the archetypal case of religious authority suppressing scientific knowledge, i

galileo galileo affair inquisition heliocentrism copernicus dialogue
H_2_06 Verified Suppression & Thesis

H_2_06 — Successful Paradigm Shifts in Archaeology: Cases Where Orthodoxy Was Wrong

The history of science contains well-documented cases where firmly held orthodoxies were overturned by new evidence, often after decades of resistance from established authorities. Thomas Kuhn's The Structure of Scientif

paradigm shift Thomas Kuhn Clovis First pre-Clovis Monte Verde Göbekli Tepe
P_5_02 Verified Philosophy & Meaning

P_5_02 — Computational Phylogenetics of Mythology

This document examines Computational Phylogenetics of Mythology, a topic within the Philosophy Meaning research area. Key areas of investigation include The Traditional Approach: Comparative Mythology, The Biological Ana

phylogenetics mythology Yuri Berezkin Julien d'Huy Michael Witzel Laurasian
ZE_1_01 Verified Ethics & Applied Philosophy

ZE_1_01 — Ethics Across Civilizations: Universal Moral Patterns

Despite vast cultural differences, virtually every civilization in human history has independently developed strikingly similar core moral principles: reciprocity (the Golden Rule), prohibitions against murder and theft,

ethics morality Golden Rule natural law moral universals deontology
R_4_12 Verified Biology & Evolution

R_4_12 — Mimicry: Batesian, Müllerian, and Aggressive Deception

Mimicry — the resemblance of one organism (the mimic) to another (the model) or to an environmental feature, evolved to deceive a third party (the signal receiver, typically a predator) — is one of the most elegant demon

mimicry Batesian mimicry Müllerian mimicry aggressive mimicry aposematism warning coloration
R_3_02 Verified Biology & Evolution

R_3_02 — Horizontal Gene Transfer in Complex Life

For decades, the "tree of life" was the central metaphor of evolutionary biology — species branching neatly from common ancestors through vertical gene transmission (parent to offspring). This metaphor is now BROKEN, at

horizontal gene transfer HGT lateral gene transfer LGT endosymbiosis mitochondria
R_5_03 Verified Biology & Evolution

R_5_03 — Domestication of Plants and Agriculture

The domestication of plants — one of the most transformative events in human history — began independently in at least 10 geographic centers between ~12,000 and 5,000 years ago. The Fertile Crescent (wheat, barley, lenti

domestication agriculture Neolithic revolution Fertile Crescent teosinte maize
R_5_10 Verified Biology & Evolution

R_5_10 — Plant Defense: Chemical Warfare, Thorns, and Allelopathy

Plants, being sessile organisms unable to flee from herbivores, have evolved an extraordinary arsenal of defenses — mechanical, chemical, and ecological — that collectively represent one of evolution's most creative solu

plant defense secondary metabolite alkaloid terpene tannin phenolic
R_2_05 Verified Biology & Evolution

R_2_05 — Missing Fossil Record and Punctuated Equilibrium

Darwin himself called the fossil record "the most obvious and gravest objection which can be urged against my theory" — because if evolution occurred through gradual transformation, we should find smooth transitional seq

fossil record transitional fossil missing link punctuated equilibrium Gould Eldredge
R_2_13 Verified Biology & Evolution

R_2_13 — Mammalian Radiation: Post-Cretaceous Diversification

The Cretaceous-Paleogene (K-Pg) mass extinction 66 million years ago — triggered by an asteroid impact and possibly exacerbated by Deccan Traps volcanism — eliminated the non-avian dinosaurs and opened vast ecological ni

mammalian radiation adaptive radiation Cretaceous-Paleogene extinction K-Pg boundary placental mammal marsupial
R_2_03 Verified Biology & Evolution

R_2_03 — Neanderthal Cognition and Interbreeding

For over a century, Neanderthals were depicted as brutish, cognitively inferior "cave men" — a failed evolutionary experiment replaced by superior modern humans. This narrative has been DEMOLISHED by 21st-century genetic

Neanderthal Homo neanderthalensis hybridization interbreeding DNA genome
R_2_06 Verified Biology & Evolution

R_2_06 — Isbell Snake Detection Hypothesis

This document examines Isbell Snake Detection Hypothesis, a topic within the Biology Evolution research area. Key areas of investigation include Origin and Author, The Core Thesis, The Expanded Pulvinar. The analysis spa

Lynne Isbell snake detection theory primate vision pulvinar nucleus trichromatic vision Quan Van Le
R_2_08 Verified Biology & Evolution

R_2_08 — Bipedalism — Why We Walk Upright and What It Cost Us

Bipedalism — habitual upright walking on two legs — is the defining characteristic of the hominin lineage, predating brain enlargement, tool use, and language by millions of years. The earliest evidence comes from Sahela

bipedalism human evolution Sahelanthropus Ardipithecus Laetoli footprints savanna hypothesis