RESEARCH BASE

Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

2,528 results for "CI" — page 8 of 127

Z_2_18 Verified Molecular Biology

Z_2_18 — Pharmacogenomics and Precision Medicine

Pharmacogenomics — the study of how genetic variation affects individual responses to drugs — aims to replace the "one-size-fits-all" prescribing model with genotype-guided therapy, selecting the right drug at the right

pharmacogenomics precision-medicine drug-metabolism cyp450 warfarin adverse-drug-reactions
Z_2_16 Verified Molecular Biology

Z_2_16 — Cancer Genomics & Precision Oncology

Cancer genomics — the comprehensive analysis of the genetic alterations that drive cancer initiation, progression, and resistance to therapy — has transformed oncology from a tissue-of-origin classification system into a

cancer genomics precision oncology tumor sequencing oncogene tumor suppressor somatic mutation
K_3_09 Consciousness

K_3_09 — Minimal Consciousness and the Threshold of Sentience

Where does consciousness begin? This question — the problem of the threshold of sentience — is one of the most challenging in consciousness studies because it requires identifying what KIND of physical system is minimall

minimal consciousness sentience threshold consciousness markers biological consciousness single cell behavior bacterial cognition
K_3_06 Consciousness

K_3_06 — Disorders of Consciousness: Coma, Vegetative State, and Minimal Consciousness

Disorders of consciousness (DoC) — coma, vegetative state (now termed unresponsive wakefulness syndrome/UWS), and minimally conscious state (MCS) — represent some of the most challenging clinical and philosophical proble

disorders of consciousness coma vegetative state UWS unresponsive wakefulness syndrome minimally conscious state locked-in syndrome
K_3_19 Verified Consciousness

K_3_19 — Electrical Synapses and Gap Junctions in Consciousness

Most neuroscience focuses on chemical synapses, but the brain also uses electrical synapses formed by connexin-36 gap junctions — direct cytoplasmic channels that pass ions and small molecules between neurons. These prov

electrical synapse gap junction connexin pannexin ephaptic coupling neural synchrony
K_3_10 Consciousness

K_3_10 — Fetal and Infant Consciousness

The question of when consciousness emerges during human development — whether prenatally, at birth, or gradually through infancy — is one of the most consequential in consciousness studies, with direct implications for f

fetal consciousness infant consciousness neonatal consciousness prenatal awareness fetal pain cortical development
K_3_01 Consciousness

K_3_01 — Machine Consciousness — Can AI Be Aware?

The question of machine consciousness — whether artificial systems can be genuinely aware rather than merely simulating awareness — stands at the intersection of philosophy of mind, neuroscience, and computer science. Jo

machine consciousness Chinese Room Turing Test Integrated Information Theory IIT Phi
K_3_16 Verified Consciousness

K_3_16 — Anesthesia and Consciousness: What Going Under Reveals

General anesthesia provides a unique experimental window into consciousness: the ability to reversibly abolish and restore awareness in a controlled clinical setting. Despite over 175 years of practice since William T.G.

anesthesia-consciousness general-anesthesia propofol ketamine sevoflurane awareness-under-anesthesia
K_3_14 Credible Consciousness

K_3_14 — Consciousness in Octopuses and Distributed Nervous Systems

Octopuses (Octopus vulgaris, O. bimaculoides, Abdopus aculeatus, and ~300 other species in order Octopoda) represent perhaps the most profound natural experiment in the evolution of consciousness: they are the most cogni

octopus cephalopod consciousness distributed nervous system invertebrate cognition mollusc
K_3_08 Consciousness

K_3_08 — Intention, Volition, and Motor Consciousness

The neural basis of voluntary action and the timing of conscious intention relative to brain activity has become one of the most productive — and philosophically consequential — research programs in consciousness studies

free will neuroscience volition Bereitschaftspotential readiness potential Libet experiment Benjamin Libet
K_3_15 Verified Consciousness

K_3_15 — Anesthesia and the Mechanisms of Consciousness Loss

General anesthesia — the reversible abolition of consciousness through pharmacological agents — is one of the most remarkable phenomena in medicine: it routinely eliminates subjective experience in millions of patients d

anesthesia consciousness-loss general-anesthesia neural-correlates propofol sevoflurane
K_3_12 Verified Consciousness

K_3_12 — Blindsight and Unconscious Vision: Seeing Without Awareness

Blindsight is a neurological phenomenon in which individuals who are cortically blind — having lost conscious visual experience in part or all of their visual field due to damage to the primary visual cortex (V1/striate

blindsight unconscious vision V1 striate cortex Weiskrantz cortical blindness
K_3_13 Verified Consciousness

K_3_13 — Coma, Vegetative State, and Minimally Conscious State: Clinical Boundaries

Disorders of consciousness (DoC) — clinical conditions in which awareness (the content of consciousness — perception, thought, experience) and/or arousal (the level of wakefulness — eyes open, sleep-wake cycles) are seve

coma vegetative state minimally conscious state unresponsive wakefulness syndrome disorders of consciousness locked-in syndrome
K_3_17 Verified Consciousness

K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects

The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica

psychedelic psilocybin DMT dimethyltryptamine LSD 5-HT2A receptor
K_3_11 Verified Consciousness

K_3_11 — Animal Consciousness and Sentience

The question of whether non-human animals possess conscious experience — subjective awareness, felt pain, emotions, and self-recognition — has moved from philosophical speculation to a major neuroscientific research prog

animal consciousness sentience Cambridge Declaration mirror test Gallup pain perception
K_3_07 Consciousness

K_3_07 — Evolution of Consciousness

The question of when, how, and why consciousness evolved is one of the deepest unsolved problems at the intersection of biology, neuroscience, and philosophy. Two major recent proposals have attempted to identify the evo

evolution of consciousness consciousness origins sentience evolution Cambrian consciousness nervous system evolution neural correlates evolution
K_3_04 Consciousness

K_3_04 — Anesthesia and Consciousness

General anesthesia — the reversible, drug-induced abolition of consciousness — is one of medicine's greatest achievements and, paradoxically, one of its least understood. Approximately 350 million surgical procedures per

anesthesia general anesthesia consciousness propofol sevoflurane ketamine
K_3_18 Verified Consciousness

K_3_18 — Bioelectricity and Consciousness Transitions

Conscious experience tracks specific patterns of bioelectric activity in neural tissue, and every clinically validated method of producing unconsciousness — general anesthesia, deep sleep, hypothermic circulatory arrest,

bioelectricity consciousness transitions anesthesia mechanism ion channels membrane potential neural decoherence
K_3_03 Consciousness

K_3_03 — Memory and Consciousness

Memory and consciousness are deeply intertwined — memory provides the continuity of experience that creates a sense of self persisting through time, while consciousness provides the subjective context within which memori

memory consciousness working memory episodic memory autobiographical memory amnesia
K_1_03 Consciousness

K_1_03 — Free Energy Principle and Predictive Processing

The Free Energy Principle (FEP), developed by neuroscientist Karl Friston (2006-present), is one of the most ambitious theoretical frameworks in 21st-century science: it attempts to explain the EXISTENCE, BEHAVIOR, and C

free energy principle FEP Karl Friston predictive processing predictive coding active inference