RESEARCH BASE

Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

362 results for "selfish genetic element" — page 7 of 19

T_1_04 Psychology & Social

T_1_04 — Developmental Psychology — From Piaget to Attachment Theory

Developmental psychology traces psychological changes across the human lifespan, from prenatal development through aging. Jean Piaget's cognitive stage theory, Lev Vygotsky's sociocultural approach, John Bowlby's attachm

developmental psychology Piaget cognitive stages Vygotsky scaffolding Bowlby
ZD_1_02 Information & Computation

ZD_1_02 — Information Theory — Shannon, Entropy, and the Bit

Claude Shannon's 1948 paper "A Mathematical Theory of Communication" is one of the most consequential scientific publications of the 20th century. It defined information quantitatively — measured in bits — independent of

information theory Claude Shannon entropy bit channel capacity noise
ZD_4_08 Verified Information & Computation

ZD_4_08 — Bioinformatics and Computational Biology

Bioinformatics — the application of computational methods to biological data, especially molecular sequences — has become indispensable to modern biology. The field emerged from the convergence of molecular biology's dat

bioinformatics computational biology sequence alignment BLAST genome assembly phylogenetics
L_1_04 Genetics & Origins

L_1_04 — Archaic Human Species Synthesis

The human evolutionary tree is far more complex than the older linear model suggested. Fossils, ancient DNA, and proteomics now show that Homo sapiens overlapped with several other hominin lineages, including Neanderthal

archaic humans Neanderthal Denisovan Homo floresiensis hobbit Homo luzonensis
L_1_09 Genetics & Origins

L_1_09 — Ghost Populations & Missing Archaic Lineages

Ghost populations are human groups whose existence is inferred from statistical signatures in modern or ancient genomes rather than from direct fossil or archaeological evidence. The term reflects a central challenge of

ghost population archaic introgression missing lineage unsampled population West African introgression superarchaic
L_1_03 Genetics & Origins

L_1_03 — Mitochondrial Eve, Y-Chromosomal Adam & Population Origins

Mitochondrial Eve and Y-chromosomal Adam are the most recent common ancestors of all living humans along strictly maternal and strictly paternal lines. They were not the first woman and man, were not a couple, and do not

mitochondrial Eve Y-chromosomal Adam mtDNA haplogroup Out of Africa Jebel Irhoud
L_1_12 Verified Genetics & Origins

L_1_12 — Ghost DNA: Unknown Archaic Hominin Admixture

"Ghost DNA" refers to genetic signals — segments of the genome, deviations in allele frequency distributions, or anomalous phylogenetic patterns — that indicate admixture (interbreeding) between anatomically modern human

ghost DNA archaic admixture unknown hominin introgression ancient DNA aDNA
L_4_07 Verified Genetics & Origins

L_4_07 — Twin Studies and Heritability

Twin studies represent one of the most powerful natural experiments in human genetics, exploiting the fact that monozygotic (MZ, "identical") twins share ~100% of their DNA while dizygotic (DZ, "fraternal") twins share ~

twin study monozygotic dizygotic heritability concordance ACE model
L_4_15 Verified Genetics & Origins

L_4_15 — Y-Chromosome and mtDNA Mismatch Patterns in Human Populations

The Y chromosome (paternally inherited, non-recombining) and mitochondrial DNA (maternally inherited) provide independent genealogical records of male and female lineage histories, respectively. When these two markers te

y-chromosome mitochondrial-dna sex-biased-migration patrilocality matrilocality haplogroup
L_2_18 Verified Genetics & Origins

L_2_18 — Archaic Admixture in Africa (Ghost Populations)

While Neanderthal and Denisovan admixture in non-African populations has been well-documented since Svante Pääbo's landmark 2010 Neanderthal genome paper, evidence for archaic admixture within Africa represents a more re

archaic admixture ghost population African genetics ancient DNA introgression archaic hominin
L_3_16 Verified Genetics & Origins

L_3_16 — Genomic Imprinting & Evolutionary Conflict

Genomic imprinting — the epigenetic phenomenon in which a subset of genes (~100–200 in mammals) are expressed from only one parental allele, with the other allele silenced by DNA methylation and histone modification esta

genomic imprinting parent-of-origin expression epigenetics kinship theory parental conflict IGF2
L_5_03 Verified Genetics & Origins

L_5_03 — Pharmacogenomics and Ancestral Medicine

Pharmacogenomics — the study of how genetic variation influences individual responses to drugs — bridges genetics, pharmacology, and clinical medicine. Humans carry extensive polymorphism in genes encoding drug-metaboliz

pharmacogenomics CYP2D6 CYP2C_5_04 drug metabolism personalized medicine warfarin
Y_4_02 Altered States

Y_4_02 — Savant Syndrome and Acquired Genius

Savant syndrome — extraordinary ability coexisting with significant cognitive disability — affects roughly 1 in 10 people with autism and ~1 in 2,000 people with other developmental disabilities or brain injuries. What m

savant syndrome acquired savant traumatic brain injury autistic savant Kim Peek Daniel Tammet
H_4_04 Suppression & Thesis

H_4_04 — Soviet Science Suppression — Lysenkoism and Vavilov

The Lysenko affair (1928–1964) represents the most devastating case of ideological suppression of science in the 20th century. Trofim Denisovich Lysenko (1898–1976), an agronomist with minimal formal training, rose to do

Lysenko Lysenkoism Vavilov Soviet genetics ideological science Lamarckism
ZE_3_17 Verified Ethics & Applied Philosophy

ZE_3_17 — CRISPR Ethics: Gene Editing and the Future of Humanity

The development of CRISPR-Cas9 gene editing — demonstrated by Jennifer Doudna and Emmanuelle Charpentier in 2012 (Nobel Prize in Chemistry, 2020) — created the most precise, accessible, and affordable tool for modifying

CRISPR-Cas9 gene editing germline editing He Jiankui somatic editing designer babies
R_3_08 Biology & Evolution

R_3_08 — Speciation Mechanisms and Reproductive Isolation

Speciation — the process by which one species splits into two or more reproductively isolated lineages — is the engine of biodiversity. Ernst Mayr's biological species concept (1942) defines species as groups of interbre

speciation reproductive isolation allopatric speciation sympatric speciation peripatric speciation parapatric speciation
R_3_11 Biology & Evolution

R_3_11 — Microevolution and Rapid Adaptation

Microevolution — changes in allele frequencies within populations over generations — is the fundamental engine of biological adaptation. Once assumed to operate too slowly to observe directly, research over the past 50 y

microevolution rapid adaptation contemporary evolution natural selection genetic drift gene flow
R_3_02 Biology & Evolution

R_3_02 — Horizontal Gene Transfer in Complex Life

For decades, the "tree of life" was the central metaphor of evolutionary biology — species branching neatly from common ancestors through vertical gene transmission (parent to offspring). This metaphor is now BROKEN, at

horizontal gene transfer HGT lateral gene transfer LGT endosymbiosis mitochondria
R_5_18 Verified Biology & Evolution

R_5_18 — Synthetic Biology & Artificial Genomes

Synthetic biology is an interdisciplinary field that applies engineering principles — standardization, modular design, abstraction hierarchies — to biological systems, with the ultimate goal of designing and constructing

synthetic biology artificial genome JCVI-syn3.0 minimal cell Craig Venter xenobiology
ZB_1_03 Ecology & Biology

ZB_1_03 — Artificial Life, Emergence, and Digital Evolution

Artificial life (ALife) is an interdisciplinary field studying life-as-it-could-be through computational, chemical, and robotic systems that exhibit lifelike behaviors — self-replication, evolution, emergence, and adapta

artificial life ALife emergence cellular automata Conway Game of Life Wolfram