RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

1,650 results for "human chromosome 2" — page 63 of 83

L_4_12 Verified Genetics & Origins

L_4_12 — CRISPR Gene Drives and Population Genetics Ethics

CRISPR gene drives — genetic engineering systems that combine CRISPR-Cas9 gene editing with super-Mendelian inheritance to spread a modified gene through an entire wild population far faster than natural selection — repr

CRISPR Cas9 gene drive population genetics gene editing malaria
L_2_08 Verified Genetics & Origins

L_2_08 — East Asian Genetics and Population History

East Asia — comprising China, Japan, Korea, Mongolia, Taiwan, and mainland Southeast Asia — is home to the largest human population concentration on Earth and harbors a complex genetic history shaped by major north-south

East Asian genetics Chinese population Japanese genetics Korean genetics Han Chinese Jomon
L_2_11 Verified Genetics & Origins

L_2_11 — Ancient DNA and the Indo-European Question

The Indo-European question — where was the homeland of the Proto-Indo-European (PIE) language, and how did the Indo-European family spread to encompass languages from Ireland to India? — has been one of the most debated

Indo-European Yamnaya steppe Corded Ware ancient DNA language dispersal
L_2_16 Verified Genetics & Origins

L_2_16 — Genetic Diversity and Inbreeding: Population Health Across History

Genetic diversity — the total amount of genetic variation within a population — is a fundamental determinant of population health, adaptive potential, and long-term survival. The loss of diversity through inbreeding (mat

genetic diversity inbreeding consanguinity runs of homozygosity ROH inbreeding depression
L_2_15 Verified Genetics & Origins

L_2_15 — Population Structure of the Ancient Near East: Farming Spread Genetics

The Neolithic Revolution — the independent invention of agriculture in the Fertile Crescent (~10,000-8,000 BCE) — was one of the most consequential transformations in human history, and ancient DNA has revealed that the

Neolithic farming Near East Fertile Crescent Anatolia Levant
L_2_13 Verified Genetics & Origins

L_2_13 — Genetic History of Island Southeast Asia: Wallace Line and Beyond

Island Southeast Asia (ISEA) — the vast archipelagic region encompassing the Philippines, Indonesia, Timor, and the islands between mainland Asia and Australo-Papua — is one of the most genetically complex regions on Ear

Island Southeast Asia ISEA Wallace Line Wallacea Sunda Sahul
L_3_17 Verified Genetics & Origins

L_3_17 — Endogenous Retroviruses (HERVs) in the Human Genome

Human endogenous retroviruses (HERVs) — remnants of ancient retroviral infections that integrated into the germline DNA of human ancestors and have been vertically transmitted through the host genome for millions of year

endogenous retroviruses HERVs HERV-K HERV-W syncytin retroviral integration
L_5_16 Verified Genetics & Origins

L_5_16 — Archaeogenetics: Ancient DNA and the Human Past

Archaeogenetics — the extraction and analysis of DNA from ancient human, animal, and plant remains — has transformed our understanding of human history since the field's breakthrough in 2010. Advances in next-generation

archaeogenetics ancient DNA aDNA paleogenomics Svante Pääbo David Reich
L_5_12 Credible Genetics & Origins

L_5_12 — Microbiome-Consciousness Connection: Gut-Brain Axis and Microbial Influence on Mind

The microbiome-gut-brain axis — the bidirectional communication network linking the ~38 trillion microorganisms inhabiting the human gastrointestinal tract with the central nervous system — has emerged as one of the most

microbiome gut-brain axis psychobiotics vagus nerve serotonin Cryan
L_5_02 Verified Genetics & Origins

L_5_02 — Genetic Diseases and Founder Effect Populations

When a small group founds a new population and subsequently expands in relative isolation, genetic drift can amplify alleles that were rare in the ancestral population — including deleterious recessive disease alleles. T

founder effect genetic disease Tay-Sachs sickle cell cystic fibrosis Ashkenazi
Y_4_02 Verified Altered States

Y_4_02 — Savant Syndrome and Acquired Genius

Savant syndrome — extraordinary ability coexisting with significant cognitive disability — affects roughly 1 in 10 people with autism and ~1 in 2,000 people with other developmental disabilities or brain injuries. What m

savant syndrome acquired savant traumatic brain injury autistic savant Kim Peek Daniel Tammet
Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
Y_4_22 Credible Altered States

Y_4_22 — Hypnagogic & Hypnopompic States

Hypnagogia (the transitional state between wakefulness and sleep onset) and hypnopompia (the transition from sleep to waking) are naturally occurring altered states of consciousness experienced universally by humans. Cha

hypnagogia hypnopompia sleep onset phosphenes tetris effect sleep paralysis
Y_4_20 Credible Altered States

Y_4_20 — Drumming & Trance Neuroscience

Shamanic drumming — typically monotonous percussive rhythms at approximately 4–4.5 beats per second — has been used across virtually every indigenous culture as a primary technology for inducing trance states, and modern

drumming trance theta rhythm auditory driving EEG entrainment
Y_4_21 Credible Altered States

Y_4_21 — Fasting-Induced Altered States

Fasting-induced altered states of consciousness — visionary experiences, euphoria, time distortion, dissociation, and mystical-type experiences produced by prolonged food deprivation — represent one of humanity's oldest

fasting altered states ketosis beta-hydroxybutyrate vision quest asceticism
Y_5_02 Verified Altered States

Y_5_02 — CIA Gateway Process, Monroe Institute & Hemi-Sync

The CIA's Gateway Process Analysis Report (1983) is a declassified U.S. Army Intelligence document that evaluated the Monroe Institute's Hemi-Sync technology for potential military/intelligence applications. Written by L

Gateway Process Gateway Experience Monroe Institute Hemi-Sync binaural beats Robert Monroe
Y_5_12 Speculative Altered States

Y_5_12 — Dark Retreat: Extended Light Deprivation and Endogenous Visionary States

The dark retreat (yangti nagpo or mun mtshams in Tibetan) is an advanced contemplative practice — primarily within the Dzogchen (Great Perfection) tradition of Tibetan Buddhism and the closely related Bön tradition — in

dark retreat yangti Tibetan Buddhism melatonin DMT hypothesis light deprivation
Y_5_20 Verified Altered States

Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks

MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w

MDMA ecstasy entactogen empathogen serotonin PTSD therapy
Y_5_22 Credible Altered States

Y_5_22 — Brainwave Entrainment: Neural Oscillation, Binaural Beats, and Auditory Driving

Brainwave entrainment refers to the capacity of external rhythmic stimuli — auditory, visual, or electromagnetic — to synchronize endogenous neural oscillation patterns toward the frequency of the stimulus, a phenomenon

brainwave entrainment binaural beats auditory driving neural oscillation EEG alpha waves
Y_2_05 Credible Altered States

Y_2_05 — Near-Death Experiences: Cross-Cultural Analysis

Near-death experiences (NDEs) — profound subjective experiences occurring during clinical death, cardiac arrest, or perceived proximity to death — have been reported across virtually all cultures and historical periods.

near-death experience NDE cross-cultural NDE tunnel experience life review being of light out-of-body experience