RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,279 results for "ion channel" — page 60 of 164

Y_3_06 Credible Altered States

Y_3_06 — Awe, Wonder, and Transcendent Emotions

Awe — the emotional response to perceived vastness that requires accommodation (cognitive restructuring of existing mental schemas) — has emerged as a frontier topic in affective neuroscience, positive psychology, and ph

awe wonder transcendent emotion self-transcendence vastness accommodation
Y_1_12 Credible Altered States

Y_1_12 — Salvia Divinorum: Mazatec Sage and Kappa-Opioid Visionary

Salvia divinorum ("diviner's sage") is a psychoactive plant of the mint family (Lamiaceae) native to the cloud forests of the Sierra Mazateca in Oaxaca, Mexico, where it has been used for centuries by Mazatec healers and

Salvia divinorum salvinorin A kappa-opioid receptor Mazatec divination sage
Y_1_07 Credible Altered States

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

ego dissolution psychedelic neuroscience default mode network psilocybin LSD DMT
P_3_05 Verified Philosophy & Meaning

P_3_05 — Philosophy of Science — Demarcation, Method, and Progress

The philosophy of science investigates the foundations, methods, and implications of science — asking what distinguishes science from non-science (the demarcation problem), how scientific theories are confirmed or refute

philosophy of science Popper falsificationism Kuhn paradigm shift Lakatos
P_4_19 Credible Philosophy & Meaning

P_4_19 — Indian Logic Traditions

The Indian traditions of logic and epistemology (pramāṇa-śāstra) represent one of the most sophisticated and independently developed systems of formal reasoning in human intellectual history, spanning over two millennia

Indian logic Nyaya pramana anumana inference Dignaga
P_4_08 Verified Philosophy & Meaning

P_4_08 — Ubuntu and African Philosophical Traditions

African philosophy encompasses a rich and diverse family of intellectual traditions far too often overlooked in global philosophical discourse. Ubuntu — "I am because we are" (umuntu ngumuntu ngabantu) — is the most wide

Ubuntu African philosophy Yoruba Ori Akan Sankofa
P_1_17 Credible Philosophy & Meaning

P_1_17 — Artificial Intelligence and the Consciousness Question

The question of whether artificial systems can possess consciousness — genuine subjective experience, phenomenal awareness, or "something it is like" to be that system (Thomas Nagel, 1974) — has moved from philosophical

artificial-intelligence machine-consciousness chinese-room hard-problem large-language-models sentience
P_1_11 Verified Philosophy & Meaning

P_1_11 — The Demiurge: Creator God in Philosophy and Religion

The Demiurge (from Greek dēmiourgos, "craftsman" or "artisan") is a concept of a divine creator figure responsible for fashioning the physical universe, most famously developed in Plato's dialogue Timaeus (~360 BCE) and

demiurge Plato Timaeus Gnosticism creator craftsman
P_5_09 Verified Philosophy & Meaning

P_5_09 — Wittgenstein: Language Games, Tractatus, and Investigations

Ludwig Josef Johann Wittgenstein (1889-1951) is unique in the history of philosophy for having produced two profoundly influential but largely incompatible philosophical systems. His first major work, the Tractatus Logic

Wittgenstein Ludwig Wittgenstein Tractatus Logico-Philosophicus Philosophical Investigations language games picture theory
P_5_18 Verified Philosophy & Meaning

P_5_18 — Comparative Religion & the Science of Sacred Traditions

Comparative religion — the systematic study of the world's religious traditions through cross-cultural analysis — emerged as an academic discipline in the 19th century with Friedrich Max Müller's translation of the Sacre

comparative religion history of religions Mircea Eliade Joseph Campbell phenomenology of religion sacred and profane
P_2_16 Credible Philosophy & Meaning

P_2_16 — Philosophy of Law: Natural Law, Legal Positivism, and the Foundations of Justice

The philosophy of law (jurisprudence) addresses the fundamental questions: What is law? What is the relationship between law and morality? What makes a legal system legitimate? and how should judges decide difficult case

philosophy of law jurisprudence natural law legal positivism Hart Fuller
ZE_5_06 Verified Ethics & Applied Philosophy

ZE_5_06 — Ethics of Whistleblowing: Loyalty, Truth, and Institutional Accountability

Whistleblowing — the disclosure by a member of an organization of illegal, unethical, or harmful activities to parties capable of taking corrective action — forces a direct confrontation between competing moral obligatio

whistleblowing loyalty truth accountability Snowden Manning
ZE_5_15 Verified Ethics & Applied Philosophy

ZE_5_15 — Ethics of Disability: Social Models, Access, and Inclusion

The ethics of disability has been transformed over the past five decades by the shift from the medical model — which defines disability as individual pathology to be cured or managed — to the social model — which defines

disability disability ethics social model medical model access inclusion
ZE_5_14 Verified Ethics & Applied Philosophy

ZE_5_14 — Ethics of Promise and Contract: Trust, Binding Words, and Obligation

Promise-keeping is among the most fundamental moral obligations — yet its philosophical basis is surprisingly elusive. Why does uttering certain words ("I promise") create a binding moral obligation? The question has gen

promise contract obligation trust fidelity promissory obligation
ZE_5_10 Verified Ethics & Applied Philosophy

ZE_5_10 — Ethics of Silence and Complicity: Bystander Problem and Moral Inaction

Moral inaction — the failure to intervene, speak, or resist in the face of injustice — is one of the most pervasive and consequential forms of ethical failure. The bystander effect, famously studied after the murder of K

silence complicity bystander effect moral inaction omission Kitty Genovese
ZE_5_02 Credible Ethics & Applied Philosophy

ZE_5_02 — Ethics of Cultural Appropriation: Borrowing, Theft, and Appreciation

Cultural appropriation — the adoption of elements (dress, music, cuisine, religious symbols, hairstyles, language) from one culture by members of another, typically from a marginalized or minority culture by members of a

cultural appropriation borrowing cultural exchange cultural theft appreciation identity
ZE_5_09 Verified Ethics & Applied Philosophy

ZE_5_09 — Ethics of Automation and Labor: Displacement, UBI, and Human Purpose

Automation ethics confronts the moral dimensions of technological change that displaces human labor — a process that has accelerated dramatically with advances in artificial intelligence, robotics, and digital platforms.

automation labor work unemployment UBI universal basic income
ZE_4_12 Verified Ethics & Applied Philosophy

ZE_4_12 — Ethics of Lying and Deception: Kant, White Lies, and Noble Lies

The ethics of lying and deception stands among the oldest and most persistently debated problems in moral philosophy. At its core lies an apparent tension: truthfulness seems foundational to human communication, trust, a

lying deception Kant Bok noble lie white lies
ZE_4_07 Verified Ethics & Applied Philosophy

ZE_4_07 — Ethics of Colonialism and Reparations

The ethics of colonialism and reparations examines the moral dimensions of European imperial expansion (c. 1492–1960s and its ongoing legacies), the transatlantic slave trade, settler colonialism, and the question of wha

colonialism reparations imperialism slavery decolonization colonial ethics
ZE_3_22 Credible Ethics & Applied Philosophy

ZE_3_22 — Longevity Ethics & Life Extension: Moral Dimensions of Radical Lifespan Enhancement

The prospect of radical life extension — extending human lifespan from the current ~80-year average in developed countries to 150, 500, or even indefinite years through senolytics, gene therapy, organ replacement, AI-dri

longevity-ethics life-extension anti-aging radical-lifespan immortality-ethics geroscience-ethics