RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,271 results for "ion channels" — page 59 of 164

Y_5_16 Credible Altered States

Y_5_16 — Breathwork Traditions: Pranayama, Holotropic, Tummo & Physiological Mechanisms

Deliberate manipulation of breathing patterns — breathwork — represents one of humanity's oldest and most cross-culturally widespread technologies for inducing altered states of consciousness, modulating autonomic functi

breathwork pranayama holotropic-breathing tummo hyperventilation respiratory-alkalosis
Y_5_05 Speculative Altered States

Y_5_05 — Psychic Phenomena: Meta-Analyses and Scientific Evaluation

Parapsychology — the scientific study of purported psychic (psi) phenomena including telepathy, clairvoyance, precognition, and psychokinesis — occupies a unique and contested position in science. Over 130+ years, thousa

parapsychology psi research telepathy clairvoyance precognition psychokinesis
Y_5_07 Verified Altered States

Y_5_07 — Phenomenology of Pain and Pain Modulation

Pain — defined by the International Association for the Study of Pain (IASP, revised 2020) as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissu

pain nociception pain modulation gate control theory Melzack Wall
Y_5_15 Verified Altered States

Y_5_15 — Altitude Sickness and High-Altitude Consciousness: Mountain Visions

Altitude sickness — a spectrum of syndromes caused by hypobaric hypoxia (reduced oxygen partial pressure at elevation) — produces some of the most dramatic and well-documented involuntary altered states of consciousness

altitude sickness hypoxia third-man factor Everest high-altitude cerebral edema HACE
Y_5_19 Verified Altered States

Y_5_19 — Congenital Insensitivity to Pain: SCN9A, Nociception, and the Neuroscience of Painlessness

Congenital insensitivity to pain (CIP) encompasses a group of rare inherited conditions in which individuals are born with absent or severely diminished pain perception while retaining other sensory modalities (touch, pr

congenital insensitivity to pain CIP CIPA SCN9A Nav1.7 nociception
Y_5_22 Credible Altered States

Y_5_22 — Brainwave Entrainment: Neural Oscillation, Binaural Beats, and Auditory Driving

Brainwave entrainment refers to the capacity of external rhythmic stimuli — auditory, visual, or electromagnetic — to synchronize endogenous neural oscillation patterns toward the frequency of the stimulus, a phenomenon

brainwave entrainment binaural beats auditory driving neural oscillation EEG alpha waves
Y_2_14 Credible Altered States

Y_2_14 — Dying Process Phenomenology: Shared Death Experiences and After-Death Communication

The phenomenology of death and the experiences reported by those who witness the dying process include several distinct categories of altered-state phenomena that extend beyond the well-known near-death experience (NDE).

shared death experience after-death communication deathbed visions grief hallucinations terminal lucidity Moody
Y_2_03 Credible Altered States

Y_2_03 — Reincarnation Research — Stevenson, Tucker, Past-Life Memories

Reincarnation research — the systematic, empirical investigation of claims that individuals (typically young children) possess verified memories of previous lives — represents one of the most methodologically rigorous pr

reincarnation past-life memories Ian Stevenson Jim Tucker birthmarks xenoglossy
Y_2_06 Verified Altered States

Y_2_06 — Dissociation, Depersonalization, and Derealization

Dissociation — the disruption of normally integrated functions of consciousness, memory, identity, emotion, perception, behavior, and sense of self — represents one of the most revealing natural experiments for understan

dissociation depersonalization derealization depersonalization-derealization disorder DDD dissociative identity disorder
Y_2_15 Credible Altered States

Y_2_15 — Breathwork Traditions: Holotropic, Tummo, and Physiological Extremes

Breathwork — the deliberate manipulation of breathing patterns to induce altered physiological and psychological states — represents one of humanity's oldest and most accessible methods for modifying consciousness, with

breathwork holotropic-breathing tummo wim-hof-method pranayama hyperventilation
Y_3_13 Credible Altered States

Y_3_13 — Visionary Art: Depicting Altered States from Hildegard to Grey

Visionary art — artistic creation inspired by, depicting, or emerging from altered states of consciousness — spans the entire history of human image-making, from Paleolithic cave paintings (whose geometric patterns David

visionary art Alex Grey Hildegard of Bingen psychedelic art Huichol entoptic phenomena
Y_3_02 Verified Altered States

Y_3_02 — Meditation, Neuroplasticity, and Contemplative Neuroscience

Meditation — the systematic training of attention and awareness — has been practiced for at least 3,000-5,000 years (earliest evidence: Indus Valley seal of a seated figure in meditation posture, ~2600 BCE; earliest text

meditation neuroplasticity mindfulness MBSR default mode network DMN
Y_3_09 Credible Altered States

Y_3_09 — Prayer, Contemplation, and the Neuroscience of Religious Experience

The neuroscientific study of prayer and religious experience — sometimes termed neurotheology (d'Aquili & Newberg, 1999) — has moved from philosophical speculation to empirical investigation using neuroimaging, EEG, and

neurotheology prayer neuroscience Andrew Newberg SPECT prayer religious experience mystical experience
Y_3_06 Credible Altered States

Y_3_06 — Awe, Wonder, and Transcendent Emotions

Awe — the emotional response to perceived vastness that requires accommodation (cognitive restructuring of existing mental schemas) — has emerged as a frontier topic in affective neuroscience, positive psychology, and ph

awe wonder transcendent emotion self-transcendence vastness accommodation
Y_1_12 Credible Altered States

Y_1_12 — Salvia Divinorum: Mazatec Sage and Kappa-Opioid Visionary

Salvia divinorum ("diviner's sage") is a psychoactive plant of the mint family (Lamiaceae) native to the cloud forests of the Sierra Mazateca in Oaxaca, Mexico, where it has been used for centuries by Mazatec healers and

Salvia divinorum salvinorin A kappa-opioid receptor Mazatec divination sage
Y_1_07 Credible Altered States

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

ego dissolution psychedelic neuroscience default mode network psilocybin LSD DMT
P_3_05 Verified Philosophy & Meaning

P_3_05 — Philosophy of Science — Demarcation, Method, and Progress

The philosophy of science investigates the foundations, methods, and implications of science — asking what distinguishes science from non-science (the demarcation problem), how scientific theories are confirmed or refute

philosophy of science Popper falsificationism Kuhn paradigm shift Lakatos
P_4_19 Credible Philosophy & Meaning

P_4_19 — Indian Logic Traditions

The Indian traditions of logic and epistemology (pramāṇa-śāstra) represent one of the most sophisticated and independently developed systems of formal reasoning in human intellectual history, spanning over two millennia

Indian logic Nyaya pramana anumana inference Dignaga
P_4_08 Verified Philosophy & Meaning

P_4_08 — Ubuntu and African Philosophical Traditions

African philosophy encompasses a rich and diverse family of intellectual traditions far too often overlooked in global philosophical discourse. Ubuntu — "I am because we are" (umuntu ngumuntu ngabantu) — is the most wide

Ubuntu African philosophy Yoruba Ori Akan Sankofa
P_1_17 Credible Philosophy & Meaning

P_1_17 — Artificial Intelligence and the Consciousness Question

The question of whether artificial systems can possess consciousness — genuine subjective experience, phenomenal awareness, or "something it is like" to be that system (Thomas Nagel, 1974) — has moved from philosophical

artificial-intelligence machine-consciousness chinese-room hard-problem large-language-models sentience