RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
3,721 results for "lamin A" — page 50 of 187
Z_4_23 — Memory as Physical and Molecular Phenomenon
What is a memory made of? The question has driven neuroscience from Santiago Ramón y Cajal's 1894 hypothesis that learning strengthens connections between neurons, through Donald Hebb's 1949 postulate that "neurons that
Z_4_10 — Signal Transduction: How Cells Communicate
Signal transduction — the molecular mechanisms by which cells detect, interpret, and respond to external signals (hormones, growth factors, neurotransmitters, cytokines, environmental cues) — is one of the central organi
Z_4_16 — Phase Separation in Cell Biology: Membraneless Organelles and Biomolecular Condensates
Liquid-liquid phase separation (LLPS) is the biophysical process by which proteins and nucleic acids demix from the surrounding cytoplasm or nucleoplasm to form concentrated, membrane-free droplets called biomolecular co
Z_4_04 — RNA Biology: Types and Functions
RNA (ribonucleic acid) — once considered merely a passive intermediary between DNA and protein — is now recognized as the most functionally diverse class of biological macromolecules, performing roles in catalysis, gene
Z_4_07 — The Tree of Life: Molecular Phylogenetics and Universal Ancestry
The Tree of Life — the branching diagram representing the evolutionary relationships among all living organisms — has been fundamentally reshaped by molecular phylogenetics, the reconstruction of evolutionary history usi
Z_4_01 — Human Microbiome, Gut-Brain Axis, and the Holobiont Concept
The human microbiome — the ~38 trillion microbial cells (bacteria, archaea, fungi, viruses) inhabiting the human body — constitutes a co-evolved ecosystem that profoundly influences health, immunity, metabolism, developm
Z_4_03 — Forensic Genetics and DNA Identification
Forensic genetics uses DNA analysis to identify individuals, establish biological relationships, and solve criminal cases — a revolution that began when Sir Alec Jeffreys (1984, University of Leicester) discovered DNA fi
Z_4_11 — The Cell Cycle: Division, Checkpoints, and Cancer
The cell cycle — the ordered series of events by which a cell grows, replicates its DNA, and divides into two daughter cells — is one of the most fundamental processes in biology and one of the most intensively studied i
Z_4_15 — Molecular Motors: Kinesin, Dynein, and Myosin
Molecular motors — protein machines that convert the chemical energy of ATP hydrolysis into directed mechanical work — are the engines of cellular life, responsible for transporting cargo within cells, driving cell divis
Z_4_22 — Protein Chaperone Systems
Molecular chaperones are a diverse group of proteins that assist other proteins in achieving and maintaining their correct three-dimensional structures — preventing misfolding, aggregation, and toxic accumulation of non-
Z_4_19 — Exosome Signaling and Intercellular Communication
Exosomes are small (30–150 nm) membrane-bound extracellular vesicles (EVs) released by virtually all cell types, carrying a cargo of proteins, lipids, mRNAs, microRNAs (miRNAs), and other nucleic acids that can be taken
Z_4_14 — RNA Interference: Gene Silencing by Small RNAs
RNA interference (RNAi) — the process by which small double-stranded RNA molecules silence gene expression by targeting complementary messenger RNA (mRNA) for degradation or translational repression — is one of the most
K_3_19 — Electrical Synapses and Gap Junctions in Consciousness
Most neuroscience focuses on chemical synapses, but the brain also uses electrical synapses formed by connexin-36 gap junctions — direct cytoplasmic channels that pass ions and small molecules between neurons. These prov
K_3_16 — Anesthesia and Consciousness: What Going Under Reveals
General anesthesia provides a unique experimental window into consciousness: the ability to reversibly abolish and restore awareness in a controlled clinical setting. Despite over 175 years of practice since William T.G.
K_3_14 — Consciousness in Octopuses and Distributed Nervous Systems
Octopuses (Octopus vulgaris, O. bimaculoides, Abdopus aculeatus, and ~300 other species in order Octopoda) represent perhaps the most profound natural experiment in the evolution of consciousness: they are the most cogni
K_3_15 — Anesthesia and the Mechanisms of Consciousness Loss
General anesthesia — the reversible abolition of consciousness through pharmacological agents — is one of the most remarkable phenomena in medicine: it routinely eliminates subjective experience in millions of patients d
K_3_12 — Blindsight and Unconscious Vision: Seeing Without Awareness
Blindsight is a neurological phenomenon in which individuals who are cortically blind — having lost conscious visual experience in part or all of their visual field due to damage to the primary visual cortex (V1/striate
K_3_13 — Coma, Vegetative State, and Minimally Conscious State: Clinical Boundaries
Disorders of consciousness (DoC) — clinical conditions in which awareness (the content of consciousness — perception, thought, experience) and/or arousal (the level of wakefulness — eyes open, sleep-wake cycles) are seve
K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects
The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica
K_3_11 — Animal Consciousness and Sentience
The question of whether non-human animals possess conscious experience — subjective awareness, felt pain, emotions, and self-recognition — has moved from philosophical speculation to a major neuroscientific research prog
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