RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

257 results for "base rate neglect" — page 5 of 13

ZF_5_01 Verified Oceanography

ZF_5_01 — Autonomous Underwater Vehicles and Ocean Exploration Technology

Ocean exploration technology — from early human-occupied submersibles to modern autonomous underwater vehicles (AUVs) — has progressively opened the deep ocean to scientific investigation, driving transformative discover

AUV autonomous underwater vehicle ROV remotely operated vehicle submersible ocean exploration
ZF_5_12 Verified Oceanography

ZF_5_12 — Paleocene-Eocene Thermal Maximum: Ancient Anoxic Ocean Crisis

The Paleocene-Eocene Thermal Maximum (PETM), occurring approximately 55.8 million years ago (latest Paleocene), was one of the most dramatic and rapid climate change events in the Cenozoic, offering the closest geologica

PETM Paleocene-Eocene Thermal Maximum hyperthermal carbon isotope excursion CIE ocean acidification
ZF_4_03 Verified Oceanography

ZF_4_03 — Desalination and Ocean Water Resources

Desalination — the removal of dissolved salts from seawater or brackish water to produce freshwater — has become an increasingly critical technology as global freshwater demand rises and climate change intensifies drough

desalination reverse osmosis water scarcity brine discharge membrane technology thermal desalination
Z_5_13 Verified Molecular Biology

Z_5_13 — Molecular Clocks: Timing Evolution at the Sequence Level

Molecular clocks — the observation that DNA and protein sequences accumulate substitutions (mutations that become fixed in a lineage) at approximately regular rates over long periods of evolutionary time, enabling the es

molecular clock neutral theory substitution rate Zuckerkandl Pauling calibration
Z_5_17 Verified Molecular Biology

Z_5_17 — CRISPR-Cas9 Mechanism and Applications

CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated protein 9) is a revolutionary genome-editing technology adapted from the natural adaptive immune system of bacteria and archaea

CRISPR Cas9 gene editing guide RNA PAM double-strand break
Z_5_01 Verified Molecular Biology

Z_5_01 — CRISPR Applications and Genetic Engineering

CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology adapted from a bacterial immune defense system, enabling precise, programmable modification of DNA in vir

CRISPR Cas9 gene editing genetic engineering CRISPR-Cas9 guide RNA
Z_3_01 Verified Molecular Biology

Z_3_01 — Genetics of Brain Development — ASPM, Microcephalin, HAR1

The human brain is approximately three times larger than expected for a primate of our body size, with a vastly expanded cerebral cortex containing ~86 billion neurons. Identifying the genetic basis for this extraordinar

ASPM microcephalin MCPH1 HAR1 human accelerated regions brain evolution
Z_2_05 Verified Molecular Biology

Z_2_05 — Gene Therapy: History and Progress

Gene therapy — the introduction, alteration, or replacement of genetic material within a patient's cells to treat or cure disease — has evolved from a speculative concept to an approved clinical reality over five decades

gene therapy gene replacement viral vector adeno-associated virus AAV lentivirus
Z_1_07 Verified Molecular Biology

Z_1_07 — Genetic Recombination and Crossing Over

Genetic recombination — the physical exchange of DNA segments between homologous chromosomes during meiosis — is a fundamental biological process that generates genetic diversity, ensures proper chromosome segregation, a

recombination crossing over meiosis chiasma homologous recombination linkage
Z_1_13 Verified Molecular Biology

Z_1_13 — DNA Repair Mechanisms and Genome Stability

Every human cell sustains an estimated 10,000–100,000 DNA lesions per day from endogenous sources alone — oxidative metabolism, spontaneous hydrolysis, replication errors, and reactive metabolites — while environmental m

DNA repair base excision repair nucleotide excision repair mismatch repair double-strand break homologous recombination
Z_1_11 Verified Molecular Biology

Z_1_11 — Polyploidy and Genome Duplication

Polyploidy — the possession of more than two complete sets of chromosomes — is a major force in genome evolution, particularly in plants and some animal lineages. Susumu Ohno (1970) proposed that whole genome duplication

polyploidy genome duplication whole genome duplication WGD autopolyploidy allopolyploidy
Z_4_05 Verified Molecular Biology

Z_4_05 — Synthetic Biology and Minimal Genomes

Synthetic biology aims to design, construct, and engineer biological systems and organisms with novel functions not found in nature — or to redesign existing biological systems for useful purposes. The field's landmark a

synthetic biology minimal genome JCVI-syn3.0 Mycoplasma mycoides synthetic cell Venter
K_3_19 Verified Consciousness

K_3_19 — Electrical Synapses and Gap Junctions in Consciousness

Most neuroscience focuses on chemical synapses, but the brain also uses electrical synapses formed by connexin-36 gap junctions — direct cytoplasmic channels that pass ions and small molecules between neurons. These prov

electrical synapse gap junction connexin pannexin ephaptic coupling neural synchrony
K_3_01 Verified Consciousness

K_3_01 — Machine Consciousness — Can AI Be Aware?

The question of machine consciousness — whether artificial systems can be genuinely aware rather than merely simulating awareness — stands at the intersection of philosophy of mind, neuroscience, and computer science. Jo

machine consciousness Chinese Room Turing Test Integrated Information Theory IIT Phi
K_3_14 Credible Consciousness

K_3_14 — Consciousness in Octopuses and Distributed Nervous Systems

Octopuses (Octopus vulgaris, O. bimaculoides, Abdopus aculeatus, and ~300 other species in order Octopoda) represent perhaps the most profound natural experiment in the evolution of consciousness: they are the most cogni

octopus cephalopod consciousness distributed nervous system invertebrate cognition mollusc
K_1_01 Credible Consciousness

K_1_01 — Quantum Consciousness & Penrose-Hameroff

The Orchestrated Objective Reduction (Orch-OR) theory — proposed by Nobel laureate Roger Penrose and anesthesiologist Stuart Hameroff — suggests consciousness arises from quantum computations in microtubules within neuro

Orch-OR orchestrated objective reduction Penrose Hameroff microtubules quantum consciousness
K_1_10 Credible Consciousness

K_1_10 — Panpsychism — Comprehensive Survey

Panpsychism — the view that consciousness or experiential properties are fundamental and ubiquitous features of the physical world — has experienced a dramatic revival in analytic philosophy since the early 2000s, driven

panpsychism panprotopsychism Chalmers Galen Strawson Russellian monism combination problem
K_1_09 Credible Consciousness

K_1_09 — Philosophical Zombies and the Hard Problem

The philosophical zombie (p-zombie) thought experiment, formalized by David Chalmers (1996), asks: Could there exist a being physically and functionally identical to a conscious human — identical atom for atom, processin

philosophical zombie p-zombie hard problem of consciousness David Chalmers explanatory gap qualia
K_4_03 Credible Consciousness

K_4_03 — Limitation of Consciousness Motif

One of the most startling cross-cultural patterns in the world's mythological and philosophical traditions: ancient civilizations worldwide — separated by thousands of miles, thousands of years, and entirely independent

limitation of consciousness eyes weakened Popol Vuh Archon control 120 years lifespan limit
K_5_05 Credible Consciousness

K_5_05 — Consciousness and Information Integration: Phi and Its Critics

Integrated Information Theory (IIT), developed primarily by neuroscientist Giulio Tononi (b. 1960) at the University of Wisconsin-Madison, with significant contributions from Christof Koch (Allen Institute for Brain Scie

integrated information theory IIT phi Tononi Koch consciousness