RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
278 results for "POS" — page 5 of 14
Z_3_05 — Viral Integration and Endogenous Retroviruses
Approximately 8% of the human genome consists of human endogenous retroviruses (HERVs) — the remnants of ancient retroviral infections that integrated into germline cells and were subsequently inherited vertically like a
Z_3_01 — Genetics of Brain Development — ASPM, Microcephalin, HAR1
The human brain is approximately three times larger than expected for a primate of our body size, with a vastly expanded cerebral cortex containing ~86 billion neurons. Identifying the genetic basis for this extraordinar
Z_1_13 — DNA Repair Mechanisms and Genome Stability
Every human cell sustains an estimated 10,000–100,000 DNA lesions per day from endogenous sources alone — oxidative metabolism, spontaneous hydrolysis, replication errors, and reactive metabolites — while environmental m
Z_1_01 — ENCODE Project, Non-Coding DNA & Epigenetics
The human genome is ~3.2 billion base pairs long, but only ~1.5% encodes proteins. The remaining ~98.5% was once dismissed as "junk DNA." The ENCODE Project (2003–present) revealed that at least 80% of the genome has bio
Z_1_18 — Junk DNA & the ENCODE Controversy: Function, Noise, and the Human Genome
The term "junk DNA" — coined by Susumu Ohno (1972) to describe non-coding DNA sequences in eukaryotic genomes that appeared to have no functional role — ignited one of the most contentious debates in modern genomics: how
Z_1_19 — Non-Coding RNA and Gene Regulation
Non-coding RNAs (ncRNAs) — RNA molecules that are transcribed from the genome but do not encode proteins — have emerged as central regulators of gene expression, challenging the classical "one gene–one protein" paradigm
Z_4_14 — RNA Interference: Gene Silencing by Small RNAs
RNA interference (RNAi) — the process by which small double-stranded RNA molecules silence gene expression by targeting complementary messenger RNA (mRNA) for degradation or translational repression — is one of the most
K_3_06 — Disorders of Consciousness: Coma, Vegetative State, and Minimal Consciousness
Disorders of consciousness (DoC) — coma, vegetative state (now termed unresponsive wakefulness syndrome/UWS), and minimally conscious state (MCS) — represent some of the most challenging clinical and philosophical proble
K_1_17 — Integrated Information Theory: Phi, Axioms & Empirical Tests
Integrated Information Theory (IIT), developed primarily by Giulio Tononi (University of Wisconsin–Madison) from 2004 to the present, proposes that consciousness is identical to integrated information — a quantity denote
K_1_03 — Free Energy Principle and Predictive Processing
The Free Energy Principle (FEP), developed by neuroscientist Karl Friston (2006-present), is one of the most ambitious theoretical frameworks in 21st-century science: it attempts to explain the EXISTENCE, BEHAVIOR, and C
K_1_06 — Predictive Processing and Consciousness
Predictive processing (PP) is a unifying framework in cognitive neuroscience proposing that the brain is fundamentally a prediction machine — it continuously generates top-down predictions of incoming sensory input and u
K_1_05 — Global Workspace Theory
Global Workspace Theory (GWT), proposed by Bernard Baars (1988) and neurally formalized by Stanislas Dehaene and Jean-Pierre Changeux as the Global Neuronal Workspace (GNW, 1998–2011), is one of the leading scientific th
K_1_09 — Philosophical Zombies and the Hard Problem
The philosophical zombie (p-zombie) thought experiment, formalized by David Chalmers (1996), asks: Could there exist a being physically and functionally identical to a conscious human — identical atom for atom, processin
K_4_21 — Quantum Approaches to Consciousness: A Rigorous Assessment
The hypothesis that consciousness depends on quantum-mechanical processes — most prominently in the Penrose-Hameroff Orchestrated Objective Reduction (Orch-OR) model — is one of the most polarizing claims in cognitive sc
K_2_05 — Unconscious Processing
The cognitive unconscious — mental processes that influence behavior, emotion, and decision-making without reaching conscious awareness — is one of the most empirically robust phenomena in psychology and neuroscience. Fa
K_2_03 — Neural Correlates of Consciousness
The neural correlates of consciousness (NCC) are the minimal neuronal mechanisms jointly sufficient for any one specific conscious experience. The systematic search for NCCs was launched by Francis Crick and Christof Koc
K_2_11 — Default Mode Network: Brain at Rest and Self-Referential Consciousness
The Default Mode Network (DMN) is a large-scale brain network that is most active when a person is not focused on the external environment — during mind-wandering, daydreaming, self-referential thought, autobiographical
K_2_13 — Attention Networks: Dorsal, Ventral, and Salience Systems
Attention — the selective allocation of processing resources to particular stimuli, locations, or tasks — is among the most studied phenomena in cognitive neuroscience and is intimately linked to consciousness: what we a
K_5_13 — Integrated World Models: Bayesian Brain and Consciousness
The Bayesian brain hypothesis proposes that the brain is fundamentally a prediction machine — it constructs and maintains internal generative models of the world (including the body), uses these models to generate predic
K_5_05 — Consciousness and Information Integration: Phi and Its Critics
Integrated Information Theory (IIT), developed primarily by neuroscientist Giulio Tononi (b. 1960) at the University of Wisconsin-Madison, with significant contributions from Christof Koch (Allen Institute for Brain Scie
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