RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
244 results for "OTO" — page 5 of 13
Z_4_05 — Synthetic Biology and Minimal Genomes
Synthetic biology aims to design, construct, and engineer biological systems and organisms with novel functions not found in nature — or to redesign existing biological systems for useful purposes. The field's landmark a
Z_4_06 — Psychedelic Neurochemistry: 5-HT2A, Tryptamines, and Molecular Mechanisms
Psychedelic neurochemistry — the molecular-level study of how psychedelic compounds alter brain function to produce their characteristic effects (visual hallucinations, synesthesia, ego dissolution, mystical-type experie
Z_4_01 — Human Microbiome, Gut-Brain Axis, and the Holobiont Concept
The human microbiome — the ~38 trillion microbial cells (bacteria, archaea, fungi, viruses) inhabiting the human body — constitutes a co-evolved ecosystem that profoundly influences health, immunity, metabolism, developm
K_3_09 — Minimal Consciousness and the Threshold of Sentience
Where does consciousness begin? This question — the problem of the threshold of sentience — is one of the most challenging in consciousness studies because it requires identifying what KIND of physical system is minimall
K_3_02 — Embodied Cognition
Embodied cognition is a broad research program challenging the classical cognitive science view that the mind is essentially a computer processing abstract symbols in the brain. Instead, embodied cognition holds that thi
K_3_12 — Blindsight and Unconscious Vision: Seeing Without Awareness
Blindsight is a neurological phenomenon in which individuals who are cortically blind — having lost conscious visual experience in part or all of their visual field due to damage to the primary visual cortex (V1/striate
K_1_10 — Panpsychism — Comprehensive Survey
Panpsychism — the view that consciousness or experiential properties are fundamental and ubiquitous features of the physical world — has experienced a dramatic revival in analytic philosophy since the early 2000s, driven
K_1_15 — Consciousness–Genetics Interface
Genetic variation significantly modulates conscious experience, including baseline personality, susceptibility to altered states, response to psychoactive substances, meditation capacity, and vulnerability to disorders o
K_4_13 — Mirror Neurons and Social Cognition
Mirror neurons are a class of neurons, first discovered in the early 1990s in the premotor cortex (area F5) of macaque monkeys by Giacomo Rizzolatti, Vittorio Gallese, and colleagues at the University of Parma, that fire
K_4_07 — Biofield Science — Electromagnetic and Subtle Energy Research
Biofield science investigates the electromagnetic, acoustic, and hypothesized "subtle energy" fields associated with living organisms, spanning a spectrum from rigorous biophysics to highly contested alternative medicine
K_2_21 — Transcranial Brain Stimulation: tDCS, TMS, and Deep Brain Stimulation
Transcranial brain stimulation encompasses a family of techniques that modulate neural activity by delivering energy — magnetic pulses, electrical current, or implanted electrodes — to specific brain regions. The three p
K_2_01 — Split-Brain Research and Divided Consciousness
Split-brain research — the study of patients whose corpus callosum has been surgically severed to treat intractable epilepsy — stands as one of neuroscience's most philosophically consequential experimental programs. Rog
K_2_14 — Brain Lateralization and Consciousness: The Divided Brain
Hemispheric lateralization — the functional specialization of the two cerebral hemispheres — is one of the most robust findings in neuroscience and has profound implications for understanding consciousness. The left hemi
E_3_15 — Sea-Level Curves: Eustatic Change from LGM to Present
Sea-level curves — graphical reconstructions of how global mean sea level has changed through time — represent one of the most important datasets in Quaternary science, recording the waxing and waning of continental ice
E_3_10 — Clathrate Gun Hypothesis
The clathrate gun hypothesis proposes that warming of ocean waters or thawing of permafrost can destabilize methane clathrates (also called methane hydrates) — ice-like crystalline structures in which methane molecules a
E_2_13 — Paleocene-Eocene Thermal Maximum
The Paleocene-Eocene Thermal Maximum (PETM) — approximately 55.8 million years ago — was the most extreme rapid warming event of the past 66 million years and is widely studied as a deep-time analog for modern anthropoge
E_2_12 — Great Oxygenation Event
The Great Oxygenation Event (GOE) — approximately 2.4–2.1 billion years ago — was one of the most transformative events in Earth's history: the first permanent rise of free molecular oxygen (O₂) in the atmosphere, from n
E_4_13 — Milankovitch Cycles and Orbital Forcing
Milankovitch cycles are periodic variations in Earth's orbital geometry that modulate the distribution and intensity of solar radiation reaching Earth's surface, driving the glacial-interglacial cycles that have dominate
E_1_11 — Comet Encke and the Taurid Complex: Recurring Cosmic Threat
Comet 2P/Encke — a short-period comet with the shortest known orbital period of any bright comet (3.3 years) — is the most prominent surviving fragment of a much larger cometary body whose progressive disintegration over
E_1_12 — Impact Winter Theory: Nuclear Winter and Chicxulub Parallels
The impact winter hypothesis describes the catastrophic global darkening and cooling that follows a major asteroid or comet impact, caused by the injection of vast quantities of dust, soot, and aerosols into the Earth's
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