RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

2,970 results for "doubt is our product" — page 46 of 149

L_4_02 Verified Genetics & Origins

L_4_02 — Mendel, Inheritance, and the Rediscovery of Genetics

Gregor Johann Mendel (1822–1884), an Augustinian friar at the St. Thomas Abbey in Brno (then part of the Austrian Empire), conducted the foundational experiments in genetics by systematically crossing garden pea plants (

Gregor Mendel Mendelian inheritance law of segregation law of independent assortment dominant recessive
L_4_15 Verified Genetics & Origins

L_4_15 — Y-Chromosome and mtDNA Mismatch Patterns in Human Populations

The Y chromosome (paternally inherited, non-recombining) and mitochondrial DNA (maternally inherited) provide independent genealogical records of male and female lineage histories, respectively. When these two markers te

y-chromosome mitochondrial-dna sex-biased-migration patrilocality matrilocality haplogroup
L_2_06 Verified Genetics & Origins

L_2_06 — South Asian Genetics and Population History

South Asia harbors one of the most genetically diverse and internally structured population histories of any world region, reflecting deep settlement, repeated admixture, and long periods of extreme endogamy. The best-su

South Asian genetics Indian subcontinent ANI ASI Ancestral North Indian Ancestral South Indian
L_3_04 Verified Genetics & Origins

L_3_04 — Y-Chromosome Phylogeny and Patrilineal Deep History

The Y chromosome, transmitted exclusively from father to son, provides a uniquely informative window into patrilineal human history.

Y-chromosome haplogroup patrilineal Y-chromosomal Adam A00 R1b
L_3_03 Verified Genetics & Origins

L_3_03 — Lactase Persistence and Gene-Culture Coevolution

Lactase persistence — the ability of adults to digest the milk sugar lactose — is the most thoroughly documented case of gene-culture coevolution in the human species. The ancestral mammalian condition is lactase non-per

lactase persistence lactose intolerance LCT gene gene-culture coevolution pastoralism dairy farming
Y_4_18 Verified Altered States

Y_4_18 — Sleep Disorders and Parasomnias: Pathologies of Consciousness in Sleep

Sleep disorders affect an estimated 50–70 million Americans and ~1 billion people globally, causing significant morbidity, mortality, and economic burden. The field was transformed by the discovery of distinct sleep stag

sleep-disorders parasomnia insomnia narcolepsy sleep-apnea rem-behavior-disorder
Y_4_09 Verified Altered States

Y_4_09 — Sensory Deprivation — Float Tanks, Dark Retreats, and Consciousness Isolation

Sensory deprivation research — the systematic reduction or elimination of sensory input to study consciousness — began with John C. Lilly's invention of the isolation/flotation tank in 1954 at the National Institute of M

sensory deprivation float tank isolation tank REST John Lilly Epsom salt
Y_5_16 Credible Altered States

Y_5_16 — Breathwork Traditions: Pranayama, Holotropic, Tummo & Physiological Mechanisms

Deliberate manipulation of breathing patterns — breathwork — represents one of humanity's oldest and most cross-culturally widespread technologies for inducing altered states of consciousness, modulating autonomic functi

breathwork pranayama holotropic-breathing tummo hyperventilation respiratory-alkalosis
Y_5_06 Verified Altered States

Y_5_06 — Extreme Environments, Isolation, and Consciousness

Extreme environments and prolonged isolation produce distinctive altered states of consciousness — hallucinations, dissociation, time distortion, the sensation of an unseen companion, and profound shifts in self-identity

isolation extreme environments polar psychology space psychology solitary confinement solo sailing
Y_5_04 Credible Altered States

Y_5_04 — Anomalous Human Abilities — Yogic Siddhis, Firewalking, and Extreme Performance

Human cultures have long documented individuals who demonstrate extraordinary physical and mental abilities that challenge conventional understanding of human limits. This document surveys the full spectrum, from well-do

siddhis firewalking Wim Hof tummo breatharianism extreme fasting
Y_2_09 Verified Altered States

Y_2_09 — Sleep Paralysis, Hypnagogia, and Liminal States

Sleep paralysis — a temporary inability to move or speak while falling asleep or waking — is one of the most universal and culturally interpreted altered states, experienced by an estimated 7.6% of the general population

sleep paralysis hypnagogia hypnopompia hypnagogic hallucination old hag kanashibari
Y_1_04 Verified Altered States

Y_1_04 — Psychedelic Renaissance — Clinical Research and Consciousness

The psychedelic renaissance — a resurgence of rigorous scientific research on psychedelic substances after decades of prohibition — has produced some of the most significant findings in 21st-century psychiatry and consci

psychedelic renaissance psilocybin MDMA therapy ketamine DMT ayahuasca
Y_1_12 Credible Altered States

Y_1_12 — Salvia Divinorum: Mazatec Sage and Kappa-Opioid Visionary

Salvia divinorum ("diviner's sage") is a psychoactive plant of the mint family (Lamiaceae) native to the cloud forests of the Sierra Mazateca in Oaxaca, Mexico, where it has been used for centuries by Mazatec healers and

Salvia divinorum salvinorin A kappa-opioid receptor Mazatec divination sage
Y_1_02 Verified Altered States

Y_1_02 — Ergot, Sacred Pharmacology, and History

This document examines Ergot, Sacred Pharmacology, and History, a topic within the Consciousness research area. Key areas of investigation include Claviceps purpurea — Biology and Chemistry, Ergot Alkaloids — The Chemist

ergot Claviceps purpurea ergotamine LSA LSD Albert Hofmann
Y_1_11 Verified Altered States

Y_1_11 — Ketamine: Dissociative Anesthetic and Consciousness Explorer

Ketamine is a dissociative anesthetic — first synthesized by Calvin Stevens in 1962 and introduced into clinical use by Edward Domino and Guenter Corssen (1966) — that has undergone a remarkable transformation from battl

ketamine dissociative anesthetic K-hole NMDA antagonist depression esketamine
Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine
Y_1_18 Verified Altered States

Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers

Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl

addiction neurochemistry dopamine-reward mesolimbic-pathway opioid-crisis tolerance-dependence
Y_1_07 Credible Altered States

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

ego dissolution psychedelic neuroscience default mode network psilocybin LSD DMT
H_2_07 Verified Suppression & Thesis

H_2_07 — Radiocarbon Dating Controversies and Calibration Disputes

Radiocarbon dating — the measurement of the radioactive isotope ¹⁴C in organic materials to determine their age — is archaeology's single most important chronological tool, having revolutionized the discipline since Will

radiocarbon dating carbon-14 calibration curve IntCal Libby half-life
P_3_01 Verified Philosophy & Meaning

P_3_01 — Epistemology — How Do We Know What We Know?

Epistemology — the branch of philosophy concerned with the nature, sources, and limits of knowledge — is arguably the most foundational discipline for any research project that evaluates claims across time, culture, and

epistemology empiricism rationalism Kant Bayesian inference falsificationism