RESEARCH BASE

Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

556 results for "gene drive" — page 4 of 28

Q_4_03 Verified Cosmology & Physics

Q_4_03 — General Relativity Tests and Confirmations

Albert Einstein's general theory of relativity (GR, 1915) has survived over a century of increasingly precise experimental tests, ranging from Solar System measurements to strong-field astrophysical observations. The cla

general relativity GR tests equivalence principle gravitational redshift perihelion precession Mercury
Verified

INTERDOC_59 — Intergenerational Trauma: A Three-Channel Synthesis (Epigenetic, Psychological, Cultural)

Trauma is empirically heritable — but not through any single mechanism. The dominant public framing (epigenetics-as-Lamarckism) is overconfident; the dominant academic counter-framing (it's all attachment / it's all cult

intergenerational trauma transgenerational epigenetic inheritance FKBP5 glucocorticoid receptor methylation Holocaust descendants Dutch Hunger Winter
ZB_2_21 Verified Ecology & Biology

ZB_2_21 — Horizontal Gene Transfer & Microbial Evolution

Horizontal gene transfer (HGT) — also called lateral gene transfer (LGT) — is the transmission of genetic material between organisms by mechanisms other than parent-to-offspring (vertical) inheritance. HGT is the dominan

horizontal gene transfer lateral gene transfer conjugation transduction transformation mobile genetic elements
ZB_2_19 Verified Ecology & Biology

ZB_2_19 — Epigenetics & Chromatin Modification

Epigenetics — literally "above genetics" — encompasses heritable changes in gene expression that occur without alterations to the DNA sequence itself. The term was coined by Conrad Hal Waddington in 1942 to describe how

epigenetics DNA methylation histone modification chromatin remodeling gene expression transgenerational inheritance
ZB_2_22 Verified Ecology & Biology

ZB_2_22 — Bioelectricity, Morphogenesis, and Regeneration

Bioelectricity — the endogenous electrical signaling produced by all living cells through ion channels, pumps, and gap junctions — has emerged as a fundamental layer of biological information processing that operates alo

bioelectricity bioelectric signaling morphogenesis regeneration Michael Levin Robert Becker
ZB_5_04 Verified Ecology & Biology

ZB_5_04 — Epigenetics in Ecology and Evolution

Epigenetics — heritable changes in gene expression that do not involve changes to the DNA sequence — has transformed understanding of how organisms respond to environmental conditions, develop, and potentially transmit a

epigenetics DNA methylation histone modification transgenerational inheritance ecological epigenetics phenotypic plasticity
ZC_2_03 Social Science

ZC_2_03 — Intergenerational & Collective Trauma

Intergenerational trauma refers to the transmission of traumatic effects from one generation to the next — a phenomenon observed across populations including Holocaust survivor families, Indigenous communities subjected

intergenerational trauma historical trauma epigenetic inheritance collective trauma van der Kolk Yehuda
G_2_08 Verified Modern Frameworks

G_2_08 — Archaeogenetics — DNA Revolution in Prehistory

Archaeogenetics — the extraction and analysis of ancient DNA (aDNA) from archaeological human, animal, and plant remains — has revolutionized our understanding of human migration, population structure, admixture, kinship

archaeogenetics ancient DNA aDNA paleogenomics genome migration
L_1_11 Verified Genetics & Origins

L_1_11 — Convergent Genetic Evolution — Same Solutions, Different Lineages

Convergent evolution — the independent evolution of similar features in species from different evolutionary lineages — is one of the most powerful demonstrations of natural selection's predictability and one of the deepe

convergent evolution parallel evolution molecular convergence homoplasy adaptation natural selection
L_1_07 Genetics & Origins

L_1_07 — Genetic Bottlenecks, Founder Effects, and Toba

Genetic bottlenecks — dramatic reductions in population size that slash genetic diversity — and founder effects — the reduced variation carried by small colonizing groups — have profoundly shaped the genomes of species f

genetic bottleneck founder effect Toba catastrophe supervolcano effective population size Ashkenazi founder
L_4_06 Verified Genetics & Origins

L_4_06 — Epigenetics and Transgenerational Inheritance

Epigenetics — the study of heritable changes in gene expression that occur without alterations to the DNA sequence itself — has transformed modern biology by revealing a layer of regulatory information "above" the genome

epigenetics DNA methylation histone modification chromatin transgenerational inheritance imprinting
L_4_03 Genetics & Origins

L_4_03 — Genetic Clocks and Molecular Dating

The molecular clock — the concept that DNA and protein sequences accumulate mutations at approximately regular rates over time — provides a powerful tool for dating evolutionary divergences independently of the fossil re

molecular clock mutation rate molecular dating divergence time substitution rate neutral theory
L_4_17 Credible Genetics & Origins

L_4_17 — Transgenerational Epigenetic Trauma

Transgenerational epigenetic inheritance of trauma — the hypothesis that severe stress, famine, or psychological trauma experienced by one generation can alter the epigenetic marks (DNA methylation, histone modifications

transgenerational epigenetics epigenetic inheritance trauma cortisol PTSD Holocaust survivors
L_4_02 Genetics & Origins

L_4_02 — Mendel, Inheritance, and the Rediscovery of Genetics

Gregor Johann Mendel (1822–1884), an Augustinian friar at the St. Thomas Abbey in Brno (then part of the Austrian Empire), conducted the foundational experiments in genetics by systematically crossing garden pea plants (

Gregor Mendel Mendelian inheritance law of segregation law of independent assortment dominant recessive
L_4_11 Speculative Genetics & Origins

L_4_11 — Genetic Engineering in Ancient Mythology — Directed Modification Claims

Across virtually every major mythological tradition, human creation is depicted as a deliberate act of divine engineering — gods fashioning humans from raw materials (clay, blood, corn, breath, bone) through intentional,

genetic engineering mythology Anunnaki Enki creation myth hybridization
L_4_08 Verified Genetics & Origins

L_4_08 — Genetic Genealogy and Forensic Genomics

Genetic genealogy — the use of DNA testing for genealogical purposes — has undergone an explosive expansion since the early 2000s, driven by direct-to-consumer (DTC) genetic testing companies (23andMe, AncestryDNA, MyHer

genetic genealogy forensic DNA DNA profiling STR SNP array direct-to-consumer genetic testing
L_2_02 Genetics & Origins

L_2_02 — Population Genetics and Hardy-Weinberg Equilibrium

Population genetics — the mathematical study of allele frequency change in populations — provides the quantitative framework underlying evolutionary biology. The Hardy-Weinberg principle (1908), independently derived by

population genetics Hardy-Weinberg equilibrium allele frequency genetic drift natural selection migration
L_2_08 Verified Genetics & Origins

L_2_08 — East Asian Genetics and Population History

East Asia — comprising China, Japan, Korea, Mongolia, Taiwan, and mainland Southeast Asia — is home to the largest human population concentration on Earth and harbors a complex genetic history shaped by major north-south

East Asian genetics Chinese population Japanese genetics Korean genetics Han Chinese Jomon
L_2_17 Verified Genetics & Origins

L_2_17 — Pacific Islander Genetics: Austronesian Ancestry, Denisovan Introgression, and Oceanian Genomics

Pacific Islander populations — spanning Melanesia, Micronesia, and Polynesia — harbor some of the most genetically complex and scientifically informative genomes in human biology. Their genetic history records multiple d

Pacific Islander genetics Oceanian genomics Denisovan introgression Polynesian motif Austronesian ancestry Melanesian genetics
L_2_16 Verified Genetics & Origins

L_2_16 — Genetic Diversity and Inbreeding: Population Health Across History

Genetic diversity — the total amount of genetic variation within a population — is a fundamental determinant of population health, adaptive potential, and long-term survival. The loss of diversity through inbreeding (mat

genetic diversity inbreeding consanguinity runs of homozygosity ROH inbreeding depression