RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

944 results for "West African Iron Age" — page 34 of 48

L_1_04 Verified Genetics & Origins

L_1_04 — Archaic Human Species Synthesis

The human evolutionary tree is far more complex than the older linear model suggested. Fossils, ancient DNA, and proteomics now show that Homo sapiens overlapped with several other hominin lineages, including Neanderthal

archaic humans Neanderthal Denisovan Homo floresiensis hobbit Homo luzonensis
L_1_03 Verified Genetics & Origins

L_1_03 — Mitochondrial Eve, Y-Chromosomal Adam & Population Origins

Mitochondrial Eve and Y-chromosomal Adam are the most recent common ancestors of all living humans along strictly maternal and strictly paternal lines. They were not the first woman and man, were not a couple, and do not

mitochondrial Eve Y-chromosomal Adam mtDNA haplogroup Out of Africa Jebel Irhoud
L_1_07 Verified Genetics & Origins

L_1_07 — Genetic Bottlenecks, Founder Effects, and Toba

Genetic bottlenecks — dramatic reductions in population size that slash genetic diversity — and founder effects — the reduced variation carried by small colonizing groups — have profoundly shaped the genomes of species f

genetic bottleneck founder effect Toba catastrophe supervolcano effective population size Ashkenazi founder
L_4_07 Verified Genetics & Origins

L_4_07 — Twin Studies and Heritability

Twin studies represent one of the most powerful natural experiments in human genetics, exploiting the fact that monozygotic (MZ, "identical") twins share ~100% of their DNA while dizygotic (DZ, "fraternal") twins share ~

twin study monozygotic dizygotic heritability concordance ACE model
L_4_04 Credible Genetics & Origins

L_4_04 — Ancient Proteomics and Paleoproteomics

Paleoproteomics — the recovery and analysis of ancient proteins from archaeological and paleontological specimens — has emerged as a revolutionary complement to ancient DNA (aDNA), dramatically extending the temporal and

paleoproteomics ancient proteins collagen fingerprinting ZooMS mass spectrometry MALDI-TOF
L_4_06 Verified Genetics & Origins

L_4_06 — Epigenetics and Transgenerational Inheritance

Epigenetics — the study of heritable changes in gene expression that occur without alterations to the DNA sequence itself — has transformed modern biology by revealing a layer of regulatory information "above" the genome

epigenetics DNA methylation histone modification chromatin transgenerational inheritance imprinting
L_4_12 Verified Genetics & Origins

L_4_12 — CRISPR Gene Drives and Population Genetics Ethics

CRISPR gene drives — genetic engineering systems that combine CRISPR-Cas9 gene editing with super-Mendelian inheritance to spread a modified gene through an entire wild population far faster than natural selection — repr

CRISPR Cas9 gene drive population genetics gene editing malaria
L_4_10 Verified Genetics & Origins

L_4_10 — Sex Chromosome Evolution

Sex chromosomes — the genetic elements that determine biological sex in many organisms — represent one of the most remarkable stories in genome evolution. In mammals, the XX/XY system prevails: females have two X chromos

sex chromosome X chromosome Y chromosome sex determination SRY dosage compensation
L_2_16 Verified Genetics & Origins

L_2_16 — Genetic Diversity and Inbreeding: Population Health Across History

Genetic diversity — the total amount of genetic variation within a population — is a fundamental determinant of population health, adaptive potential, and long-term survival. The loss of diversity through inbreeding (mat

genetic diversity inbreeding consanguinity runs of homozygosity ROH inbreeding depression
L_2_12 Verified Genetics & Origins

L_2_12 — Paleogenomics of Africa: The Cradle Revisited

Africa is the cradle of human evolution — the continent where Homo sapiens originated, where the deepest branches of the human family tree diverge, and where the greatest genetic diversity in our species is found. Yet pa

Africa paleogenomics ancient DNA African population structure deep divergence Khoe-San
L_5_01 Verified Genetics & Origins

L_5_01 — Human Microbiome and Co-Evolution

The human microbiome — the aggregate community of microorganisms (bacteria, archaea, fungi, viruses, protists) living on and within the human body — comprises roughly 38 trillion microbial cells (Sender et al., 2016, Cel

microbiome gut bacteria metagenomics holobiont dysbiosis Firmicutes
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
L_5_04 Verified Genetics & Origins

L_5_04 — Ancient Microbiome and Paleomicrobiology

Paleomicrobiology — the study of ancient microorganisms through the application of molecular techniques (ancient DNA extraction, metagenomics, proteomics) to archaeological and paleontological material — has revolutioniz

microbiome paleomicrobiology ancient DNA aDNA dental calculus coprolite
L_5_02 Verified Genetics & Origins

L_5_02 — Genetic Diseases and Founder Effect Populations

When a small group founds a new population and subsequently expands in relative isolation, genetic drift can amplify alleles that were rare in the ancestral population — including deleterious recessive disease alleles. T

founder effect genetic disease Tay-Sachs sickle cell cystic fibrosis Ashkenazi
Y_4_02 Verified Altered States

Y_4_02 — Savant Syndrome and Acquired Genius

Savant syndrome — extraordinary ability coexisting with significant cognitive disability — affects roughly 1 in 10 people with autism and ~1 in 2,000 people with other developmental disabilities or brain injuries. What m

savant syndrome acquired savant traumatic brain injury autistic savant Kim Peek Daniel Tammet
Y_4_04 Verified Altered States

Y_4_04 — Entoptic Phenomena and Phosphene Patterns

This document examines Entoptic Phenomena and Phosphene Patterns, a topic within the Consciousness research area. Key areas of investigation include Defining Entoptic Phenomena, Phosphenes: Light from Within, Heinrich Kl

entoptic phenomena phosphene form constants Heinrich Klüver mescaline Lewis-Williams
Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
Y_4_07 Verified Altered States

Y_4_07 — Hypnosis — History, Neuroscience, and Therapeutic Application

Hypnosis has evolved from Franz Mesmer's "animal magnetism" theory (1770s) through James Braid's neurological reframing (1843) and James Esdaile's surgical applications in India to Milton Erickson's indirect hypnotherapy

hypnosis mesmerism Mesmer James Braid James Esdaile Milton Erickson
Y_4_03 Verified Altered States

Y_4_03 — Shamanic Practices / Altered States Synthesis

Shamanic practices represent humanity's oldest spiritual technology, attested across every inhabited continent from at least 30,000 BCE (Upper Paleolithic cave art) to the present day. Despite vast cultural distances — g

shamanism altered states Mircea Eliade ecstasy trance soul journey
Y_5_18 Credible Altered States

Y_5_18 — Sensory Deprivation & Float Tanks

Sensory deprivation — the systematic reduction or elimination of external sensory input — has been studied scientifically since the 1950s, with two primary paradigms: chamber REST (Restricted Environmental Stimulation Te

sensory deprivation flotation REST isolation tank John Lilly Epsom salt theta waves