RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
270 results for "rational medicine" — page 3 of 14
J_4_02 — Ancient Medicine and Healing Traditions
Ancient healing traditions represent some of humanity's most sophisticated technological achievements, yet are frequently underestimated by modern observers who conflate ritual context with practical ineffectiveness. Egy
L_4_17 — Transgenerational Epigenetic Trauma
Transgenerational epigenetic inheritance of trauma — the hypothesis that severe stress, famine, or psychological trauma experienced by one generation can alter the epigenetic marks (DNA methylation, histone modifications
L_5_03 — Pharmacogenomics and Ancestral Medicine
Pharmacogenomics — the study of how genetic variation influences individual responses to drugs — bridges genetics, pharmacology, and clinical medicine. Humans carry extensive polymorphism in genes encoding drug-metaboliz
Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption
Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon
R_3_15 — Epigenetics and Lamarckian Inheritance: Transgenerational Mechanisms Beyond DNA Sequence
Epigenetics — the study of heritable changes in gene expression that occur without alteration to the underlying DNA sequence — has fundamentally reshaped modern biology since the term was coined by Conrad Hal Waddington
S_2_12 — Personalized Medicine: Pharmacogenomics and Precision Health
Personalized medicine (also called precision medicine) tailors medical treatment to the individual characteristics of each patient — particularly their genetic makeup, but also incorporating biomarkers, environmental fac
S_2_06 — Regenerative Medicine and Bioprinting
Regenerative medicine aims to repair, replace, or regenerate damaged tissues and organs using biological approaches — tissue engineering, stem cell therapy, bioprinting, and xenotransplantation. The organ shortage crisis
X_5_26 — Psychedelic Medicine: The Johns Hopkins Center and the Therapeutic Renaissance
The psychedelic therapy renaissance — centered at the Johns Hopkins Center for Psychedelic and Consciousness Research (established 2019, originally launched as a research program in 2000) — represents one of the most sig
X_5_27 — Stem Cell Medicine and Regenerative Therapy
Stem cell medicine — the therapeutic use of cells capable of self-renewal and differentiation into specialized cell types — has progressed from a theoretical concept to clinical reality over six decades. James Till and E
X_3_21 — Pulmonology & Respiratory Medicine
Pulmonology encompasses the diagnosis and treatment of disease affecting the respiratory system — from upper airways to alveolar gas exchange. Respiratory diseases collectively represent the third leading cause of death
INTERDOC_74 — Transgenerational Epigenetic Inheritance: Confirmed Mechanisms and Honest Limits
[KEY FINDING] Specific environmentally-induced epigenetic states (notably from severe famine and from controlled fear-conditioning paradigms) can survive embryonic reprogramming and influence offspring phenotype across o
Z_3_02 — Epigenetic Inheritance & Transgenerational Effects
Epigenetic inheritance refers to the transmission of phenotypic information across generations through mechanisms other than changes in DNA sequence. The three primary molecular mechanisms — DNA methylation, histone modi
K_4_06 — Collective Trauma, Cultural Memory, and Intergenerational Transmission
Collective trauma — the psychological impact of catastrophic events on entire communities, nations, or peoples — and its intergenerational transmission across generations is one of the most important intersections of psy
INTERDOC_59 — Intergenerational Trauma: A Three-Channel Synthesis (Epigenetic, Psychological, Cultural)
Trauma is empirically heritable — but not through any single mechanism. The dominant public framing (epigenetics-as-Lamarckism) is overconfident; the dominant academic counter-framing (it's all attachment / it's all cult
ZC_5_21 — Intergenerational Trauma: Epigenetic Inheritance and Collective Wounds
Intergenerational trauma (also transgenerational or historical trauma) refers to the transmission of traumatic effects from one generation to subsequent generations through psychological, behavioral, social, and — contro
ZC_2_03 — Intergenerational & Collective Trauma
Intergenerational trauma refers to the transmission of traumatic effects from one generation to the next — a phenomenon observed across populations including Holocaust survivor families, Indigenous communities subjected
L_4_06 — Epigenetics and Transgenerational Inheritance
Epigenetics — the study of heritable changes in gene expression that occur without alterations to the DNA sequence itself — has transformed modern biology by revealing a layer of regulatory information "above" the genome
Y_1_21 — Plant Medicine & Alkaloid Chemistry
Alkaloids — nitrogen-containing organic compounds produced by plants as secondary metabolites — constitute one of the most important classes of biologically active molecules in both medicine and human culture. Over 20,00
ZE_3_15 — Ethics of Climate Justice: Intergenerational, Global, and Species Equity
Climate justice addresses the ethical dimensions of climate change — arguably the most consequential moral challenge facing humanity. The crisis is fundamentally unjust in three dimensions: globally, the nations least re
X_2_12 — Sound Healing and Vibroacoustic Therapy
Sound healing encompasses a broad spectrum of practices — from ancient ritual use of chanting, drums, and singing bowls to modern clinical applications of vibroacoustic therapy (VAT), music therapy, and therapeutic ultra
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