RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

607 results for "gene therapy" — page 22 of 31

Y_4_09 Verified Altered States

Y_4_09 — Sensory Deprivation — Float Tanks, Dark Retreats, and Consciousness Isolation

Sensory deprivation research — the systematic reduction or elimination of sensory input to study consciousness — began with John C. Lilly's invention of the isolation/flotation tank in 1954 at the National Institute of M

sensory deprivation float tank isolation tank REST John Lilly Epsom salt
Y_5_05 Speculative Altered States

Y_5_05 — Psychic Phenomena: Meta-Analyses and Scientific Evaluation

Parapsychology — the scientific study of purported psychic (psi) phenomena including telepathy, clairvoyance, precognition, and psychokinesis — occupies a unique and contested position in science. Over 130+ years, thousa

parapsychology psi research telepathy clairvoyance precognition psychokinesis
Y_5_19 Verified Altered States

Y_5_19 — Congenital Insensitivity to Pain: SCN9A, Nociception, and the Neuroscience of Painlessness

Congenital insensitivity to pain (CIP) encompasses a group of rare inherited conditions in which individuals are born with absent or severely diminished pain perception while retaining other sensory modalities (touch, pr

congenital insensitivity to pain CIP CIPA SCN9A Nav1.7 nociception
Y_2_02 Verified Altered States

Y_2_02 — Terminal Lucidity

This document examines Terminal Lucidity, a topic within the Consciousness research area. Key areas of investigation include What Is Terminal Lucidity?, Why This Is Anomalous, The Significance for Consciousness Studies.

terminal lucidity paradoxical lucidity near-death lucidity deathbed phenomena Nahm Greyson
Y_2_08 Verified Altered States

Y_2_08 — Anesthesia, Consciousness, and Awareness

General anesthesia — the pharmacological induction of unconsciousness, amnesia, analgesia, and immobility — is one of the most profound alterations of consciousness that humans routinely produce, yet how anesthetics actu

anesthesia general anesthesia consciousness awareness under anesthesia anesthetic awareness ether
Y_3_07 Credible Altered States

Y_3_07 — Music, Consciousness, and Altered States

Music is one of the most powerful modulators of conscious experience available without pharmacological intervention. Neuroimaging reveals that music engages an extraordinarily distributed network: auditory cortex (superi

music cognition music neuroscience chills frisson musical emotion default mode network music auditory cortex
Y_1_04 Verified Altered States

Y_1_04 — Psychedelic Renaissance — Clinical Research and Consciousness

The psychedelic renaissance — a resurgence of rigorous scientific research on psychedelic substances after decades of prohibition — has produced some of the most significant findings in 21st-century psychiatry and consci

psychedelic renaissance psilocybin MDMA therapy ketamine DMT ayahuasca
Y_1_17 Verified Altered States

Y_1_17 — Ketamine Therapy and Dissociative Medicine

Ketamine — a dissociative anesthetic synthesized by Calvin Stevens at Parke-Davis in 1962 and first used clinically by Edward Domino and Guenter Corssen in 1966 — has emerged as a revolutionary treatment for treatment-re

ketamine esketamine spravato depression treatment-resistant nmda-receptor
Y_1_11 Verified Altered States

Y_1_11 — Ketamine: Dissociative Anesthetic and Consciousness Explorer

Ketamine is a dissociative anesthetic — first synthesized by Calvin Stevens in 1962 and introduced into clinical use by Edward Domino and Guenter Corssen (1966) — that has undergone a remarkable transformation from battl

ketamine dissociative anesthetic K-hole NMDA antagonist depression esketamine
Y_1_18 Verified Altered States

Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers

Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl

addiction neurochemistry dopamine-reward mesolimbic-pathway opioid-crisis tolerance-dependence
Y_1_07 Credible Altered States

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

ego dissolution psychedelic neuroscience default mode network psilocybin LSD DMT
Y_1_10 Credible Altered States

Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption

Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon

ibogaine iboga Tabernanthe iboga Bwiti addiction interruption opioid withdrawal
H_2_16 Credible Suppression & Thesis

H_2_16 — Dissident Scientists: Careers Destroyed by Heterodox Views

The history of science includes numerous cases of researchers whose careers were damaged, marginalized, or destroyed because they advanced ideas that contradicted the prevailing scientific paradigm — ideas that were, in

dissident heterodox heresy career suppression paradigm
H_1_07 Verified Suppression & Thesis

H_1_07 — Nazi Cultural Theft and Book Burning

The Nazi regime conducted two parallel campaigns of cultural destruction and theft between 1933 and 1945: the public burning and censorship of books deemed "un-German" (undeutsch) beginning with the May 10, 1933 book bur

Nazi book burning Bücherverbrennung May 1933 degenerate art Entartete Kunst ERR
H_3_01 Verified Suppression & Thesis

H_3_01 — Indigenous Knowledge Suppression — Colonialism and Epistemicide

Epistemicide — the systematic destruction of rival knowledge systems — is arguably the most devastating and least acknowledged consequence of global colonialism. Between 1492 and 1950, European colonial powers destroyed,

epistemicide indigenous knowledge colonialism imperialism cultural suppression residential schools
H_3_04 Verified Suppression & Thesis

H_3_04 — Destruction of Aboriginal Australian Knowledge Systems

The destruction of Aboriginal Australian knowledge systems represents the disruption of the longest continuous cultural tradition on Earth — spanning at least 65,000 years. From the arrival of the First Fleet in 1788, co

Aboriginal Australians Stolen Generations songlines Dreaming Dreamtime language extinction
H_3_17 Verified Suppression & Thesis

H_3_17 — Linguistic Genocide: Language Suppression as Cultural Erasure

Linguistic genocide — the systematic, deliberate destruction of a people's language as a means of cultural erasure — has been a consistent tool of colonial and authoritarian regimes worldwide. Distinguished from natural

linguistic genocide language suppression cultural erasure boarding schools language death linguicide
H_4_13 Verified Suppression & Thesis

H_4_13 — Tobacco Science — How Industries Manufactured Doubt

The tobacco industry's half-century campaign to deny the health effects of smoking (c. 1953–2006) is the most thoroughly documented case of corporate science manipulation in history — and the template from which virtuall

tobacco science manufactured doubt merchants of doubt tobacco playbook Hill and Knowlton tobacco industry research committee
H_4_16 Credible Suppression & Thesis

H_4_16 — Pharmaceutical Suppression of Natural Remedies

The claim that the pharmaceutical industry systematically suppresses natural and herbal remedies to protect its patent-based profit model is one of the most widespread beliefs in alternative medicine — and one that conta

pharmaceutical suppression natural remedies herbal medicine Big Pharma drug patents botanical medicine
H_4_06 Verified Suppression & Thesis

H_4_06 — Suppression of Psychedelic Research (1960s–2000s)

From the late 1940s through the mid-1960s, psychedelic substances — particularly LSD (lysergic acid diethylamide) and psilocybin — were the subject of extensive legitimate scientific research, with over 1,000 peer-review

psychedelics Schedule I LSD psilocybin MDMA Controlled Substances Act