RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

32 results for "transgenerational inheritance" — page 2 of 2

Z_2_09 Verified Molecular Biology

Z_2_09 — Mitochondrial Genetics and Diseases

Human mitochondrial DNA (mtDNA) is a 16,569-bp circular genome encoding 37 genes: 13 proteins (all subunits of the oxidative phosphorylation/OXPHOS complexes I, III, IV, and V), 22 transfer RNAs, and 2 ribosomal RNAs. Un

mitochondrial genetics mtDNA mitochondrial DNA mitochondrial disease oxidative phosphorylation OXPHOS
Z_1_06 Verified Molecular Biology

Z_1_06 — Sex Determination Genetics

Sex determination — the biological process that establishes whether an organism develops as male, female, or an alternative reproductive type — employs remarkably diverse mechanisms across the tree of life. In placental

sex determination sex chromosomes X chromosome Y chromosome SRY gene X-inactivation
Z_1_01 Verified Molecular Biology

Z_1_01 — ENCODE Project, Non-Coding DNA & Epigenetics

The human genome is ~3.2 billion base pairs long, but only ~1.5% encodes proteins. The remaining ~98.5% was once dismissed as "junk DNA." The ENCODE Project (2003–present) revealed that at least 80% of the genome has bio

ENCODE non-coding DNA junk DNA epigenetics regulatory elements endogenous retrovirus
Z_4_23 Verified Molecular Biology

Z_4_23 — Memory as Physical and Molecular Phenomenon

What is a memory made of? The question has driven neuroscience from Santiago Ramón y Cajal's 1894 hypothesis that learning strengthens connections between neurons, through Donald Hebb's 1949 postulate that "neurons that

molecular memory memory engram synaptic plasticity long-term potentiation LTP Eric Kandel
K_4_06 Verified Consciousness

K_4_06 — Collective Trauma, Cultural Memory, and Intergenerational Transmission

Collective trauma — the psychological impact of catastrophic events on entire communities, nations, or peoples — and its intergenerational transmission across generations is one of the most important intersections of psy

collective trauma cultural memory intergenerational trauma transgenerational epigenetic PTSD
Verified

INTERDOC_53 — Substrate-Independent Information Patterns: Empirical Cases

A pattern is empirically substrate-independent if the same information content is preserved across changes in the physical material carrying it. Across multiple domains, biology and physics provide concrete instances of

substrate independence information theory bioelectric memory planarian regeneration prion proteins epigenetic inheritance
G_4_07 Credible Modern Frameworks

G_4_07 — Memetics — Cultural Evolution as Darwinian Process

Memetics proposes that cultural information — ideas, behaviors, styles, skills — evolves through a Darwinian process analogous to biological evolution, with the "meme" as the cultural replicator paralleling the gene. Coi

memetics meme cultural evolution Richard Dawkins Susan Blackmore Daniel Dennett
G_2_12 Credible Modern Frameworks

G_2_12 — Cultural Evolutionary Theory — Boyd, Richerson, and Henrich

Cultural evolutionary theory — developed primarily by Robert Boyd, Peter Richerson, and Joseph Henrich — provides a rigorous, formally modeled framework for understanding how cultural traits (beliefs, practices, technolo

cultural evolution dual inheritance gene-culture coevolution social learning imitation prestige bias
L_4_12 Verified Genetics & Origins

L_4_12 — CRISPR Gene Drives and Population Genetics Ethics

CRISPR gene drives — genetic engineering systems that combine CRISPR-Cas9 gene editing with super-Mendelian inheritance to spread a modified gene through an entire wild population far faster than natural selection — repr

CRISPR Cas9 gene drive population genetics gene editing malaria
L_4_10 Verified Genetics & Origins

L_4_10 — Sex Chromosome Evolution

Sex chromosomes — the genetic elements that determine biological sex in many organisms — represent one of the most remarkable stories in genome evolution. In mammals, the XX/XY system prevails: females have two X chromos

sex chromosome X chromosome Y chromosome sex determination SRY dosage compensation
R_1_12 Verified Biology & Evolution

R_1_12 — History of Evolutionary Theory

Evolutionary theory — the unifying framework of modern biology — has itself undergone a remarkable evolution over more than two centuries. Pre-Darwinian ideas included Lamarck's transformism (1809), which proposed that o

history of evolution Darwin Wallace Origin of Species natural selection Lamarck
S_2_10 Verified Future Technology

S_2_10 — Gene Drives: Ecosystem Engineering and Extinction Technology

Gene drives are genetic engineering systems that bias inheritance in sexually reproducing organisms, causing a modified gene to spread through a wild population at rates far exceeding normal Mendelian inheritance (which

gene drive CRISPR selfish gene super-Mendelian inheritance Cas9 population genetics