RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
78 results for "psychedelic threshold" — page 2 of 4
Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks
MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w
Y_3_13 — Visionary Art: Depicting Altered States from Hildegard to Grey
Visionary art — artistic creation inspired by, depicting, or emerging from altered states of consciousness — spans the entire history of human image-making, from Paleolithic cave paintings (whose geometric patterns David
Y_1_03 — Classical Antiquity Entheogens Synthesis
This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The
Y_1_14 — Toad Venom: Bufo alvarius, 5-MeO-DMT, and Desert Sacrament
Toad venom — specifically the venom of the Sonoran Desert toad (Incilius alvarius, formerly Bufo alvarius) — contains 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), one of the most potent psychoactive tryptamines known, p
Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption
Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon
C_1_07 — Hero's Journey and the Monomyth
Joseph Campbell's "Hero's Journey" (1949) proposes that the world's mythological narratives share a single underlying structure — the monomyth — in which a hero departs from the ordinary world, undergoes initiatory trial
Z_2_12 — Genetics of Pain Perception
Pain perception — the subjective experience triggered by actual or potential tissue damage — varies enormously across individuals, with genetic factors accounting for 25–50% of the variance in pain sensitivity (twin stud
Z_2_09 — Mitochondrial Genetics and Diseases
Human mitochondrial DNA (mtDNA) is a 16,569-bp circular genome encoding 37 genes: 13 proteins (all subunits of the oxidative phosphorylation/OXPHOS complexes I, III, IV, and V), 22 transfer RNAs, and 2 ribosomal RNAs. Un
K_1_04 — Brain as Filter vs Generator
Two opposing models have dominated the consciousness debate for over a century:
K_1_15 — Consciousness–Genetics Interface
Genetic variation significantly modulates conscious experience, including baseline personality, susceptibility to altered states, response to psychoactive substances, meditation capacity, and vulnerability to disorders o
K_2_11 — Default Mode Network: Brain at Rest and Self-Referential Consciousness
The Default Mode Network (DMN) is a large-scale brain network that is most active when a person is not focused on the external environment — during mind-wandering, daydreaming, self-referential thought, autobiographical
K_5_07 — Psychophysics: Measuring the Relationship Between Mind and World
Psychophysics — literally "the physics of the soul/mind" — is the scientific study of the quantitative relationship between physical stimuli and the sensations and perceptions they produce. Founded by Gustav Theodor Fech
K_5_21 — Entoptic Phenomena: Neural Basis of Universal Visual Patterns
Entoptic phenomena are visual experiences generated within the eye or visual nervous system rather than by external stimuli. They include phosphenes (light flashes from pressure on the eye or electrical stimulation), for
E_4_08 — The 3102/3114 BCE Epoch Date Parallel
This document examines The 3102/3114 BCE Epoch Date Parallel, a topic within the Cataclysms and Chronology research area. Key areas of investigation include The Hindu Kali Yuga — February 17/18, 3102 BCE, The Maya Long C
ZG_2_15 — Language Attrition: How First Languages Are Lost
Language attrition — the process by which a previously acquired language is gradually lost by an individual speaker due to reduced use and exposure — is one of the most fascinating and practically important phenomena in
INTERDOC_62 — Chemical Language Systems: Information Encoding from Microbes to Consciousness
Bacterial quorum sensing molecules encode population-density commands with combinatorial logic-gate precision (Bassler and Losick, 2006); microbial short-chain fatty acids (SCFAs) direct host immune programming, epigenet
Mind_Body_Healing_Frontier
The scientific investigation of mind-body interactions has progressed from fringe speculation to a major research domain supported by institutional infrastructure (National Center for Complementary and Integrative Health
INTERDOC_57 — Cascade Pattern Across Civilization Resets
Three civilization-altering events — the Younger Dryas climate reversal (c. 12,800 years ago), the Late Bronze Age Collapse (c. 1177 BCE), and the Justinianic Plague (541–549 CE and centuries of recurrence) — share struc
T_5_07 — Psychology of Sacred Space and Place
Sacred space — physical locations experienced as qualitatively distinct from ordinary space, charged with spiritual significance, numinous power, or transcendent meaning — is a universal feature of human culture. From Pa
T_5_14 — Peak Experiences and Ecstasy: Maslow, Mystical States, and Transformative Moments
Peak experiences — moments of ecstatic joy, profound meaning, ego-dissolution, and felt unity with the world — were identified by Abraham Maslow (1964) as among the most important experiences in human life: rare, spontan
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