RESEARCH BASE

Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

97 results for "psychedelic response" — page 2 of 5

Y_3_13 Credible Altered States

Y_3_13 — Visionary Art: Depicting Altered States from Hildegard to Grey

Visionary art — artistic creation inspired by, depicting, or emerging from altered states of consciousness — spans the entire history of human image-making, from Paleolithic cave paintings (whose geometric patterns David

visionary art Alex Grey Hildegard of Bingen psychedelic art Huichol entoptic phenomena
Y_1_03 Altered States

Y_1_03 — Classical Antiquity Entheogens Synthesis

This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The

entheogens psychedelics mystery religions Eleusinian Mysteries kykeon ergot
Y_1_14 Credible Altered States

Y_1_14 — Toad Venom: Bufo alvarius, 5-MeO-DMT, and Desert Sacrament

Toad venom — specifically the venom of the Sonoran Desert toad (Incilius alvarius, formerly Bufo alvarius) — contains 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), one of the most potent psychoactive tryptamines known, p

5-MeO-DMT Bufo alvarius Incilius alvarius toad venom Sonoran Desert toad bufotenine
Y_1_10 Credible Altered States

Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption

Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon

ibogaine iboga Tabernanthe iboga Bwiti addiction interruption opioid withdrawal
X_2_01 Medicine & Healing

X_2_01 — Psychosomatic Medicine and Placebo Science

The placebo effect — measurable physiological change resulting from the belief or expectation of treatment rather than the treatment's pharmacological action — is among the most replicated and least understood phenomena

psychosomatic medicine placebo effect nocebo psychoneuroimmunology mind-body medicine stress response
X_5_22 Verified Medicine & Healing

X_5_22 — Paracelsus & the Birth of Chemical Medicine

Philippus Aureolus Theophrastus Bombastus von Hohenheim (1493–1541), self-named Paracelsus, was a Swiss-German physician-alchemist who revolutionized European medicine by rejecting Galenic humoral theory and introducing

Paracelsus iatrochemistry toxicology dose-response alchemy chemical medicine
X_5_18 Verified Medicine & Healing

X_5_18 — Binaural Beats: Auditory Processing, Brainwave Entrainment, and Therapeutic Claims

Binaural beats are an auditory perceptual phenomenon first described by Heinrich Wilhelm Dove in 1839: when two tones of slightly different frequencies are presented separately to each ear (e.g., 400 Hz left, 410 Hz righ

binaural beats brainwave entrainment auditory beat stimulation theta waves alpha waves frequency following response
X_5_01 Verified Medicine & Healing

X_5_01 — Venom, Toxicology, and Poison Medicine

Toxicology — the study of the adverse effects of chemical, physical, or biological agents on living organisms — and the medical management of poisoning and envenomation have ancient roots and a rich history intertwining

toxicology venom poison antivenom Mithridates arsenic
X_5_09 Verified Medicine & Healing

X_5_09 — Pharmacology: The Science of Drugs and Their Actions

Pharmacology — the science of drugs — investigates how chemical substances interact with biological systems to produce therapeutic, toxic, or other effects. The discipline encompasses pharmacokinetics (what the body does

pharmacology drug receptor pharmacokinetics pharmacodynamics clinical trials
Verified

INTERDOC_70 — Ancient Knowledge as Encoded Discovery of Biophysically Significant Parameters

The standard framing pits ancient wisdom against modern science, as if they are competing epistemologies. The evidence across ID1, ID2, and ID4 demolishes this framing by showing that the same biophysically significant p

ancient knowledge biophysical parameters sacred geometry acoustic tuning frequency-following response mechanotransduction
Credible

INTERDOC_68 — Entity Categories as Attractors in Consciousness State-Space

A recurring mystery across the corpus: why do DMT users, shamanic practitioners, near-death experiencers, medieval monks, ancient temple visitors, and modern abduction reporters describe the same limited set of entity ty

entity encounters consciousness state-space attractors DMT entities NDE beings shamanic entities
Z_3_12 Molecular Biology

Z_3_12 — Genetics of Alcohol Metabolism

The genetics of alcohol metabolism provides one of the clearest examples of how specific genetic variants influence behavior and disease risk at a population scale. Ethanol is metabolized primarily through a two-step oxi

alcohol metabolism ADH1B ALDH2 acetaldehyde Asian flush alcohol dehydrogenase
Z_2_12 Molecular Biology

Z_2_12 — Genetics of Pain Perception

Pain perception — the subjective experience triggered by actual or potential tissue damage — varies enormously across individuals, with genetic factors accounting for 25–50% of the variance in pain sensitivity (twin stud

pain genetics nociception SCN9A Nav1.7 congenital insensitivity to pain TRPV1
Z_1_13 Verified Molecular Biology

Z_1_13 — DNA Repair Mechanisms and Genome Stability

Every human cell sustains an estimated 10,000–100,000 DNA lesions per day from endogenous sources alone — oxidative metabolism, spontaneous hydrolysis, replication errors, and reactive metabolites — while environmental m

DNA repair base excision repair nucleotide excision repair mismatch repair double-strand break homologous recombination
Z_4_22 Verified Molecular Biology

Z_4_22 — Protein Chaperone Systems

Molecular chaperones are a diverse group of proteins that assist other proteins in achieving and maintaining their correct three-dimensional structures — preventing misfolding, aggregation, and toxic accumulation of non-

chaperone heat shock protein Hsp70 Hsp90 GroEL GroES
K_3_06 Consciousness

K_3_06 — Disorders of Consciousness: Coma, Vegetative State, and Minimal Consciousness

Disorders of consciousness (DoC) — coma, vegetative state (now termed unresponsive wakefulness syndrome/UWS), and minimally conscious state (MCS) — represent some of the most challenging clinical and philosophical proble

disorders of consciousness coma vegetative state UWS unresponsive wakefulness syndrome minimally conscious state locked-in syndrome
K_1_04 Consciousness

K_1_04 — Brain as Filter vs Generator

Two opposing models have dominated the consciousness debate for over a century:

filter theory reducing valve brain as receiver brain as generator William James Aldous Huxley
Y_5_03 Altered States

Y_5_03 — Stigmata, Faith Healing, and Psychosomatic Phenomena

The human body can do things under the influence of belief that should not be physically possible according to conventional medical models. The placebo effect — a "sugar pill" producing measurable physiological changes —

stigmata faith healing psychosomatic placebo effect nocebo spontaneous remission
K_2_10 Verified Consciousness

K_2_10 — Neural Entrainment: External Rhythmic Brain Synchronization

Neural entrainment — the process by which rhythmic external stimuli (sound, light, tactile vibration, or electromagnetic fields) synchronize the timing of neural oscillations in the brain — is a well-established neurophy

neural entrainment brainwave entrainment auditory entrainment photic driving rhythmic stimulation neural oscillation
K_2_11 Verified Consciousness

K_2_11 — Default Mode Network: Brain at Rest and Self-Referential Consciousness

The Default Mode Network (DMN) is a large-scale brain network that is most active when a person is not focused on the external environment — during mind-wandering, daydreaming, self-referential thought, autobiographical

default mode network DMN resting state self-referential mind-wandering autobiographical memory