RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

74 results for "positive selection" — page 2 of 4

Z_3_12 Verified Molecular Biology

Z_3_12 — Genetics of Alcohol Metabolism

The genetics of alcohol metabolism provides one of the clearest examples of how specific genetic variants influence behavior and disease risk at a population scale. Ethanol is metabolized primarily through a two-step oxi

alcohol metabolism ADH1B ALDH2 acetaldehyde Asian flush alcohol dehydrogenase
Z_2_11 Verified Molecular Biology

Z_2_11 — Genetics of Immunity and MHC Diversity

The major histocompatibility complex (MHC) — known as the human leukocyte antigen (HLA) system in humans — is the most polymorphic gene region in the human genome, encoding cell-surface glycoproteins essential for adapti

major histocompatibility complex MHC HLA human leukocyte antigen adaptive immunity antigen presentation
Z_2_07 Verified Molecular Biology

Z_2_07 — Genetics of Disease Resistance

Infectious disease has been the most powerful selective force shaping the human genome, leaving signatures across thousands of loci. The best-understood example is sickle cell disease (HbS, Glu6Val in HBB): heterozygous

disease resistance natural selection pathogen-driven selection sickle cell malaria resistance HbS
Z_2_01 Verified Molecular Biology

Z_2_01 — HLA System & Archaic Immune Inheritance

The Human Leukocyte Antigen (HLA) system is the most polymorphic region of the human genome, encoding cell-surface proteins critical to adaptive immune function. Located on chromosome 6p21.3, the Major Histocompatibility

HLA human leukocyte antigen MHC major histocompatibility complex archaic introgression Denisovan
Q_1_14 Verified Cosmology & Physics

Q_1_14 — Vacuum Energy and the Cosmological Constant Problem

The cosmological constant problem is widely regarded as the most severe fine-tuning problem in all of physics. Quantum field theory predicts that the vacuum of spacetime is not empty but seethes with zero-point fluctuati

vacuum energy cosmological constant dark energy zero-point energy quantum vacuum vacuum catastrophe
Q_1_01 Verified Cosmology & Physics

Q_1_01 — The Anthropic Principle & Fine-Tuning of the Universe

The universe appears to be astonishingly fine-tuned for the existence of complex life. Alter the cosmological constant by 1 part in 10¹²⁰, or the strong nuclear force by 0.5%, or the ratio of electromagnetic to gravitati

anthropic principle fine-tuning cosmological constant multiverse physical constants observer selection
ZB_1_02 Verified Ecology & Biology

ZB_1_02 — Social Insects — Superorganisms and Collective Intelligence

Social insects — ants, bees, wasps, and termites — represent one of evolution's most spectacular innovations: the subordination of individual reproduction to colony-level organization, producing "superorganisms" capable

eusociality social insects ants bees termites naked mole rats
ZB_4_15 Credible Ecology & Biology

ZB_4_15 — Urban Wildlife Genomics: Rapid Evolution in the Anthropocene City

Cities — covering only ~3% of Earth's land surface but housing >55% of humanity — are emerging as powerful natural laboratories for studying rapid evolution in real time. Urban wildlife genomics investigates how the extr

urban-evolution wildlife-genomics urban-adaptation heat-island pollution-adaptation urban-speciation
ZB_3_09 Verified Ecology & Biology

ZB_3_09 — Mutualism and Cooperation in Nature

Mutualism — an interspecific interaction in which both partners benefit — is one of the most important ecological relationships on Earth, underpinning ecosystem function from coral reefs to forests to the human gut. The

mutualism symbiosis cooperation reciprocal altruism cleaner fish mycorrhiza
ZC_1_12 Verified Social Science

ZC_1_12 — Industrial-Organizational Psychology

Industrial-organizational (I/O) psychology applies psychological principles to workplace behavior — encompassing personnel selection, performance evaluation, motivation, leadership, organizational culture, team dynamics,

industrial-organizational social-science I/O psychology personnel selection job performance job satisfaction organizational behavior
G_4_13 Verified Modern Frameworks

G_4_13 — HADD and Agency Detection — Why We See Beings Everywhere

The Hyperactive Agency Detection Device (HADD) — a term coined by cognitive scientist Justin Barrett (2000) building on work by Stewart Guthrie (1993) and Pascal Boyer (2001) — refers to the proposed cognitive mechanism

HADD hyperactive agency detection device agency detection cognitive science of religion Barrett Boyer
G_4_11 Verified Modern Frameworks

G_4_11 — Archaeoastronomy Methods and Systematic Evidence

Archaeoastronomy — the study of how past civilizations understood, observed, and used astronomical phenomena — has matured from a field plagued by speculative alignment claims into a rigorous interdisciplinary discipline

archaeoastronomy ethnoastronomy astronomical alignment solstice equinox stellar alignment
G_3_05 Verified Modern Frameworks

G_3_05 — Self-Organization and Emergence

Self-organization is the process by which global order arises from local interactions among components of an initially disordered system, without external direction or centralized control. Emergence is the closely relate

self-organization emergence complexity Kauffman autocatalysis autopoiesis
G_2_12 Credible Modern Frameworks

G_2_12 — Cultural Evolutionary Theory — Boyd, Richerson, and Henrich

Cultural evolutionary theory — developed primarily by Robert Boyd, Peter Richerson, and Joseph Henrich — provides a rigorous, formally modeled framework for understanding how cultural traits (beliefs, practices, technolo

cultural evolution dual inheritance gene-culture coevolution social learning imitation prestige bias
O_1_11 Verified Earth Anomalies

O_1_11 — Earthquake Lights — Comprehensive Evidence and Mechanisms

Earthquake lights (EQLs) are anomalous luminous phenomena — flashes, glows, flames, orbs, and columns of light — reported in association with earthquakes throughout recorded history. Once dismissed as anecdotal or imagin

earthquake light EQL luminous phenomenon seismic tectonic Freund
O_4_09 Verified Earth Anomalies

O_4_09 — Singing Sands, Booming Dunes, and Anomalous Desert Acoustics

Singing sands and booming dunes are natural acoustic phenomena in which sand produces audible sound — sometimes at extraordinary volume (up to 105 dB, comparable to a chainsaw at 1 m) — when disturbed by wind, avalanchin

singing sand booming dune squeaking sand sand acoustics desert sound avalanche frequency
T_1_20 Verified Psychology & Social

T_1_20 — Evolutionary Psychology Debate

Evolutionary psychology (EP) is the theoretical approach that applies principles of natural selection and adaptation to understand human psychological traits — arguing that the human mind, like the human body, is the pro

evolutionary psychology adaptationism modularity Leda Cosmides John Tooby Gould
T_1_11 Verified Psychology & Social

T_1_11 — History of Psychology

Psychology's formal history as an independent discipline spans approximately 150 years — from Wilhelm Wundt's founding of the first experimental psychology laboratory in Leipzig (1879) to the present day. The discipline

history of psychology Wundt structuralism functionalism James behaviorism
T_1_02 Verified Psychology & Social

T_1_02 — Evolutionary Psychology — The Adapted Mind

Evolutionary psychology applies Darwinian natural and sexual selection to the human mind, proposing that cognitive mechanisms evolved as functional adaptations to recurrent problems faced by ancestral hunter-gatherers in

evolutionary psychology adapted mind modular mind Tooby Cosmides EEA
T_3_01 Verified Psychology & Social

T_3_01 — Cognitive Biases & Heuristics

Cognitive biases are systematic deviations from rational judgment that arise from the brain's use of mental shortcuts (heuristics) to process complex information under uncertainty.

cognitive bias heuristic Kahneman Tversky confirmation bias anchoring