RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

37 results for "placebo immune" — page 2 of 2

X_3_02 Verified Medicine & Healing

X_3_02 — Vaccination and Immunology History

Vaccination — the deliberate stimulation of adaptive immune responses using weakened, killed, or component pathogens to provide protection against infectious disease — is among the most consequential medical intervention

vaccination immunology Edward Jenner smallpox variolation polio
Z_3_05 Verified Molecular Biology

Z_3_05 — Viral Integration and Endogenous Retroviruses

Approximately 8% of the human genome consists of human endogenous retroviruses (HERVs) — the remnants of ancient retroviral infections that integrated into germline cells and were subsequently inherited vertically like a

endogenous retrovirus ERV HERV viral integration retrovirus reverse transcriptase
Z_2_11 Verified Molecular Biology

Z_2_11 — Genetics of Immunity and MHC Diversity

The major histocompatibility complex (MHC) — known as the human leukocyte antigen (HLA) system in humans — is the most polymorphic gene region in the human genome, encoding cell-surface glycoproteins essential for adapti

major histocompatibility complex MHC HLA human leukocyte antigen adaptive immunity antigen presentation
Z_4_01 Verified Molecular Biology

Z_4_01 — Human Microbiome, Gut-Brain Axis, and the Holobiont Concept

The human microbiome — the ~38 trillion microbial cells (bacteria, archaea, fungi, viruses) inhabiting the human body — constitutes a co-evolved ecosystem that profoundly influences health, immunity, metabolism, developm

microbiome gut-brain axis holobiont microbiota bacteria gut flora
K_4_02 Verified Consciousness

K_4_02 — Stigmata, Faith Healing, and Psychosomatic Phenomena

The human body can do things under the influence of belief that should not be physically possible according to conventional medical models. The placebo effect — a "sugar pill" producing measurable physiological changes —

stigmata faith healing psychosomatic placebo effect nocebo spontaneous remission
K_5_02 Verified Consciousness

K_5_02 — Pain, Consciousness, and the Nature of Suffering

Pain is one of the most philosophically revealing phenomena in consciousness studies: it is simultaneously a sensory detection system, an emotional experience, a cognitive evaluation, and a social communication — and the

pain consciousness suffering neuroscience pain matrix neuromatrix theory Melzack gate control affective pain
ZB_2_20 Verified Ecology & Biology

ZB_2_20 — Human Microbiome & Dysbiosis

The human microbiome — the collective genome of the ~38 trillion microorganisms (bacteria, archaea, fungi, viruses) inhabiting the human body — represents a second genome interacting with host physiology in ways that are

microbiome gut-brain axis dysbiosis microbiota HMP fecal transplant
ZB_2_13 Verified Ecology & Biology

ZB_2_13 — Death Biology: Programmed Cell Death

Death in biology is not merely the passive failure of living systems but an actively regulated process at multiple levels — from individual cells to whole organisms. Programmed cell death (PCD), particularly apoptosis, w

apoptosis programmed cell death necroptosis pyroptosis ferroptosis autophagy
ZC_5_17 Credible Social Science

ZC_5_17 — Ritual Efficacy Mechanisms: How Ritual Produces Real-World Effects

Ritual — formalized, repetitive, symbolic action that is culturally prescribed and often marked as distinct from ordinary behavior — is a universal feature of human societies, found in religious ceremonies, civic commemo

ritual ritual efficacy performance theory Rappaport Turner liminality
ZC_4_04 Verified Social Science

ZC_4_04 — Medical Anthropology — Culture, Healing, and the Body

Medical anthropology — the study of how health, illness, healing, and the body are experienced, understood, and managed across cultures — is one of anthropology's most productive subfields, bridging biological and social

medical anthropology healing illness disease sickness culture
T_2_06 Verified Psychology & Social

T_2_06 — Health Psychology and Stress

Health psychology investigates how psychological, behavioral, and social factors influence health, illness, and healthcare — integrating biological and psychosocial perspectives within the biopsychosocial model (Engel, 1

health psychology stress psychoneuroimmunology fight-or-flight HPA axis cortisol
L_1_10 Verified Genetics & Origins

L_1_10 — Neanderthal Genome and Legacy in Modern Humans

The sequencing of the Neanderthal genome ranks among the most significant achievements in modern biology. Beginning with the draft genome of Green et al. (2010) and refined by later high-coverage genomes from the Altai,

Neanderthal genome Neanderthal admixture archaic introgression Vindija Altai Neanderthal Homo neanderthalensis
L_1_04 Verified Genetics & Origins

L_1_04 — Archaic Human Species Synthesis

The human evolutionary tree is far more complex than the older linear model suggested. Fossils, ancient DNA, and proteomics now show that Homo sapiens overlapped with several other hominin lineages, including Neanderthal

archaic humans Neanderthal Denisovan Homo floresiensis hobbit Homo luzonensis
Y_1_15 Credible Altered States

Y_1_15 — Micro-Dosing: Sub-Perceptual Psychedelic Use and Cognitive Effects

Micro-dosing — the practice of regularly consuming sub-perceptual doses (typically 1/10th to 1/20th of a standard recreational dose) of psychedelic substances, most commonly LSD (~10–20 micrograms) or psilocybin (~0.1–0.

microdosing sub-perceptual LSD psilocybin creativity cognitive enhancement
R_4_09 Verified Biology & Evolution

R_4_09 — Parasitism and Host-Parasite Coevolution

Parasitism — a symbiotic relationship in which one organism (the parasite) benefits at the expense of another (the host) — is arguably the most common lifestyle on Earth. By some estimates, over 40% of all described spec

parasitism host-parasite coevolution Red Queen arms race Plasmodium malaria
R_5_08 Verified Biology & Evolution

R_5_08 — Human Microbiome: Gut Ecology and Symbiotic Partnerships

The human microbiome — the vast community of trillions of microorganisms (bacteria, archaea, fungi, viruses) that inhabit the human body, primarily the gastrointestinal tract — is now recognized as a critical organ-like

microbiome gut bacteria symbiosis probiotics dysbiosis gut-brain axis
F_4_19 Verified Lost Connections

F_4_19 — Denisovan Legacy in Island Southeast Asia and Melanesia

The Denisovans — an archaic hominin group identified in 2010 from ~41,000-year-old fossils found in Denisova Cave (Altai Mountains, Siberia) — left a striking and disproportionate genetic legacy in the populations of Isl

Denisovan Denisova Cave archaic hominin introgression admixture Melanesia