RESEARCH BASE

Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

43 results for "antimicrobial resistance" — page 2 of 3

Z_5_02 Verified Molecular Biology

Z_5_02 — Metagenomics and Environmental DNA

Metagenomics — the sequencing and analysis of genetic material recovered directly from environmental samples without culturing organisms — has revealed that the vast majority of Earth's microbial diversity was invisible

metagenomics environmental DNA eDNA shotgun sequencing 16S rRNA amplicon
Z_3_07 Molecular Biology

Z_3_07 — Gene Drive Technology

Gene drives are genetic systems that bias their own inheritance to spread through a population at rates exceeding normal Mendelian expectations (~50% → ~99% transmission). Natural selfish genetic elements (transposons, m

gene drive CRISPR gene drive selfish genetic element meiotic drive super-Mendelian inheritance Anopheles
Z_2_20 Verified Molecular Biology

Z_2_20 — Prion Molecular Biology

At the molecular level, prion diseases arise from the conversion of the normal cellular prion protein (PrPᶜ) into a misfolded, aggregation-prone conformer (PrPˢᶜ) through a process that remains one of the most extraordin

prion PrP protein misfolding amyloid conformational change PrPSc
ZB_2_16 Verified Ecology & Biology

ZB_2_16 — Tardigrades: Biology of Indestructibility

Tardigrades (phylum Tardigrada, ~1,400 described species) — commonly called "water bears" or "moss piglets" — are microscopic invertebrates (0.1–1.5 mm) renowned for their extraordinary tolerance to environmental extreme

tardigrade water bear moss piglet cryptobiosis anhydrobiosis tun state
ZB_2_18 Verified Ecology & Biology

ZB_2_18 — Phage-Bacteria Coevolution: Arms Races in the Microbial World

Bacteriophages (phages) — viruses that infect and replicate within bacteria — are the most abundant biological entities on Earth (~10³¹ total particles, outnumbering bacteria ~10:1 in most environments), and their coevol

bacteriophage phage therapy CRISPR Red Queen phage-bacteria coevolution
ZB_5_21 Verified Ecology & Biology

ZB_5_21 — Lateral Gene Transfer: Horizontal Exchange and Evolutionary Implications

Lateral gene transfer (LGT), also called horizontal gene transfer (HGT), is the movement of genetic material between organisms by mechanisms other than vertical parent-to-offspring inheritance. First recognized in bacter

lateral gene transfer horizontal gene transfer HGT LGT phylogenetics tree of life
ZB_5_17 Verified Ecology & Biology

ZB_5_17 — Constructal Law & Flow Architecture: Why Nature Branches the Way It Does

Most fractal descriptions of nature are descriptive: they observe that rivers branch like blood vessels, blood vessels branch like trees, trees branch like lightning bolts, and lightning bolts branch like river deltas. A

constructal law Adrian Bejan flow architecture branching networks Murray's law river delta
ZB_4_02 Verified Ecology & Biology

ZB_4_02 — Extremophiles and Extreme Biology

Extremophiles are organisms that thrive in conditions lethal to most life — extreme heat, cold, acidity, radiation, pressure, salinity, or desiccation. Their discovery has fundamentally expanded understanding of life's b

extremophiles thermophiles halophiles acidophiles psychrophiles radiation resistance
G_4_17 Verified Modern Frameworks

G_4_17 — Microbiome Archaeology — Ancient Gut and Soil Microbes

Microbiome archaeology — the extraction and analysis of ancient microbial communities from archaeological materials (dental calculus, coprolites, mummified remains, soil sediments, ceramics) — has emerged since ~2012 as

microbiome ancient microbiome dental calculus paleomicrobiology metagenomics coprolite
T_4_01 Psychology & Social

T_4_01 — Psychology of Belief & Conspiracy Thinking

The psychology of conspiracy thinking examines why individuals adopt beliefs in secret plots by powerful actors to achieve malevolent goals — beliefs that often resist disconfirmation and form interconnected "monological

conspiracy theory belief formation pattern recognition agency detection cognitive closure epistemic trust
T_1_19 Verified Psychology & Social

T_1_19 — Depression: Neurobiology, Treatment Evolution & Cultural Perspectives

Major depressive disorder (MDD) — affecting approximately 280 million people worldwide (WHO, 2021) and ranking as the leading cause of disability globally — is a heterogeneous condition whose neurobiology remains incompl

depression major-depressive-disorder serotonin-hypothesis ssri ketamine neuroplasticity
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
H_2_17 Verified Suppression & Thesis

H_2_17 — Suppressed Knowledge Evaluation Methodology

Claims of knowledge suppression pervade both fringe and mainstream intellectual discourse. This document develops an evidence-based evaluation methodology for distinguishing genuine cases of institutional suppression (Se

knowledge suppression epistemic injustice paradigm resistance Semmelweis reflex scientific gatekeeping Bayesian evaluation
N_4_06 Secret Societies

N_4_06 — African Secret Societies (Poro, Sande, Ogboni, and Initiatory Traditions)

African secret societies — more accurately described as initiatory societies or power associations — are among the most widespread and functionally important social institutions in sub-Saharan Africa, particularly in Wes

Poro Sande Ogboni African secret societies initiation societies masquerade
R_4_07 Verified Biology & Evolution

R_4_07 — Venom Evolution and Biochemical Arms Races

Venom — a cocktail of bioactive molecules injected via a specialized delivery apparatus (fangs, stingers, harpoons, nematocysts, spurs) to subdue prey, deter predators, or aid in competition — has evolved independently o

venom toxin snake venom spider venom cone snail conotoxin
R_3_11 Biology & Evolution

R_3_11 — Microevolution and Rapid Adaptation

Microevolution — changes in allele frequencies within populations over generations — is the fundamental engine of biological adaptation. Once assumed to operate too slowly to observe directly, research over the past 50 y

microevolution rapid adaptation contemporary evolution natural selection genetic drift gene flow
R_1_04 Biology & Evolution

R_1_04 — Extremophile Biology and the Limits of Life

Life exists in conditions once considered impossible: boiling hot springs (121°C+), deep-sea hydrothermal vents at crushing pressures, Antarctic ice, pH 0 acid lakes, nuclear reactor cooling pools, kilometers below Earth

extremophile archaea tardigrade Deinococcus radiodurans thermophile psychrophile
S_4_01 Future Technology

S_4_01 — Existential Risk Taxonomy

Existential risk (x-risk) refers to any event that could permanently curtail humanity's long-term potential — including extinction, civilizational collapse without recovery, or irreversible loss of value (e.g., permanent

existential risk x-risk global catastrophic risk GCR extinction Bostrom
ZA_4_14 Verified Physics & Quantum

ZA_4_14 — Spintronics: Harnessing Electron Spin for Information Technology

Spintronics (spin electronics) — the field of physics and engineering that exploits the intrinsic spin of electrons (and its associated magnetic moment), in addition to or instead of the electron's charge, to store, proc

spintronics electron spin giant magnetoresistance GMR spin-transfer torque MRAM
I_5_11 Verified UAP Disclosure

I_5_11 — UAP Stigma and Scientific Taboo

The stigma surrounding UAP/UFO research is one of the most well-documented examples of scientific taboo — a topic that mainstream science considers illegitimate to investigate, not because evidence has been evaluated and

UAP stigma UFO taboo scientific taboo career risk Robertson Panel ridicule