RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

544 results for "PRNP gene" — page 19 of 28

L_1_01 Verified Genetics & Origins

L_1_01 — Ancient DNA & Population Genetics

Modern paleogenomics has shown that human evolution was shaped by interbreeding, population structure, and repeated demographic turnover rather than a simple single-line progression. Ancient DNA revealed previously unkno

Denisovans Denisova Cave Svante Pääbo Nobel Prize ancient DNA aDNA
L_1_18 Verified Genetics & Origins

L_1_18 — Human Migration: Out of Africa, Dispersal Patterns, and the Peopling of the World

The migration of Homo sapiens out of Africa and across the globe is one of the most extensively studied processes in human evolutionary history, now reconstructed through converging evidence from genetics (mitochondrial

human migration Out of Africa dispersal ancient DNA population genetics Homo sapiens
L_0_00 Genetics & Origins

L_0_00 — Genetics & Human Origins: Section Summary

L_2_00 Genetics & Origins

L_2_00 — Population Regional Genetics: Subfolder Summary

L_2_13 Verified Genetics & Origins

L_2_13 — Genetic History of Island Southeast Asia: Wallace Line and Beyond

Island Southeast Asia (ISEA) — the vast archipelagic region encompassing the Philippines, Indonesia, Timor, and the islands between mainland Asia and Australo-Papua — is one of the most genetically complex regions on Ear

Island Southeast Asia ISEA Wallace Line Wallacea Sunda Sahul
L_3_01 Verified Genetics & Origins

L_3_01 — Serpent Symbolism in Genetics (Caduceus / DNA)

Entwined-serpent and serpent-on-staff motifs are genuinely widespread in the historical record, and the visual resemblance between some of these images and the modern DNA double helix is obvious to modern viewers. What i

caduceus DNA double helix Ningishzida Hermes kundalini Ida Pingala
L_3_10 Verified Genetics & Origins

L_3_10 — Telomeres Aging and Longevity Genetics

Telomeres — the repetitive DNA sequences (TTAGGG in vertebrates) capping the ends of linear chromosomes — protect genome integrity by preventing chromosome ends from being recognized as double-strand breaks and triggerin

telomere telomerase aging senescence Hayflick limit shelterin
L_3_12 Verified Genetics & Origins

L_3_12 — Genetics of Pigmentation: Skin, Hair, and Eye Color Evolution

Human pigmentation — the variation in skin, hair, and eye color across populations — is one of the most visible and best-understood examples of natural selection in our species. Pigmentation is determined primarily by th

pigmentation melanin skin color SLC24A5 SLC45A2 MC1R
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
L_5_11 Verified Genetics & Origins

L_5_11 — Genetics of Altitude Adaptation: Tibet, Andes, Ethiopia

High-altitude adaptation represents one of the most dramatic and best-studied examples of natural selection in contemporary human populations. More than 140 million people worldwide live at elevations above 2,500 meters,

altitude adaptation hypoxia EPAS1 EGLN1 HIF pathway hemoglobin
Y_5_05 Speculative Altered States

Y_5_05 — Psychic Phenomena: Meta-Analyses and Scientific Evaluation

Parapsychology — the scientific study of purported psychic (psi) phenomena including telepathy, clairvoyance, precognition, and psychokinesis — occupies a unique and contested position in science. Over 130+ years, thousa

parapsychology psi research telepathy clairvoyance precognition psychokinesis
Y_5_19 Verified Altered States

Y_5_19 — Congenital Insensitivity to Pain: SCN9A, Nociception, and the Neuroscience of Painlessness

Congenital insensitivity to pain (CIP) encompasses a group of rare inherited conditions in which individuals are born with absent or severely diminished pain perception while retaining other sensory modalities (touch, pr

congenital insensitivity to pain CIP CIPA SCN9A Nav1.7 nociception
Y_2_02 Verified Altered States

Y_2_02 — Terminal Lucidity

This document examines Terminal Lucidity, a topic within the Consciousness research area. Key areas of investigation include What Is Terminal Lucidity?, Why This Is Anomalous, The Significance for Consciousness Studies.

terminal lucidity paradoxical lucidity near-death lucidity deathbed phenomena Nahm Greyson
Y_2_08 Verified Altered States

Y_2_08 — Anesthesia, Consciousness, and Awareness

General anesthesia — the pharmacological induction of unconsciousness, amnesia, analgesia, and immobility — is one of the most profound alterations of consciousness that humans routinely produce, yet how anesthetics actu

anesthesia general anesthesia consciousness awareness under anesthesia anesthetic awareness ether
H_2_16 Credible Suppression & Thesis

H_2_16 — Dissident Scientists: Careers Destroyed by Heterodox Views

The history of science includes numerous cases of researchers whose careers were damaged, marginalized, or destroyed because they advanced ideas that contradicted the prevailing scientific paradigm — ideas that were, in

dissident heterodox heresy career suppression paradigm
H_1_07 Verified Suppression & Thesis

H_1_07 — Nazi Cultural Theft and Book Burning

The Nazi regime conducted two parallel campaigns of cultural destruction and theft between 1933 and 1945: the public burning and censorship of books deemed "un-German" (undeutsch) beginning with the May 10, 1933 book bur

Nazi book burning Bücherverbrennung May 1933 degenerate art Entartete Kunst ERR
H_3_01 Verified Suppression & Thesis

H_3_01 — Indigenous Knowledge Suppression — Colonialism and Epistemicide

Epistemicide — the systematic destruction of rival knowledge systems — is arguably the most devastating and least acknowledged consequence of global colonialism. Between 1492 and 1950, European colonial powers destroyed,

epistemicide indigenous knowledge colonialism imperialism cultural suppression residential schools
H_3_04 Verified Suppression & Thesis

H_3_04 — Destruction of Aboriginal Australian Knowledge Systems

The destruction of Aboriginal Australian knowledge systems represents the disruption of the longest continuous cultural tradition on Earth — spanning at least 65,000 years. From the arrival of the First Fleet in 1788, co

Aboriginal Australians Stolen Generations songlines Dreaming Dreamtime language extinction
H_3_17 Verified Suppression & Thesis

H_3_17 — Linguistic Genocide: Language Suppression as Cultural Erasure

Linguistic genocide — the systematic, deliberate destruction of a people's language as a means of cultural erasure — has been a consistent tool of colonial and authoritarian regimes worldwide. Distinguished from natural

linguistic genocide language suppression cultural erasure boarding schools language death linguicide
H_4_13 Verified Suppression & Thesis

H_4_13 — Tobacco Science — How Industries Manufactured Doubt

The tobacco industry's half-century campaign to deny the health effects of smoking (c. 1953–2006) is the most thoroughly documented case of corporate science manipulation in history — and the template from which virtuall

tobacco science manufactured doubt merchants of doubt tobacco playbook Hill and Knowlton tobacco industry research committee