RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

460 results for "OI" — page 17 of 23

ZD_4_06 Verified Information & Computation

ZD_4_06 — Mathematical Sociology and Network Analysis

Mathematical sociology applies formal mathematical models — graph theory, probability, game theory, dynamical systems, and statistical mechanics — to understand social structures, collective behavior, and institutional d

network analysis social network graph theory small world scale-free network centrality
ZD_4_09 Verified Information & Computation

ZD_4_09 — Signal Processing and Fourier Analysis

Signal processing — the analysis, modification, and synthesis of signals (time-varying or spatially varying quantities) — is fundamental to telecommunications, audio engineering, image processing, radar, medical imaging,

signal processing Fourier transform FFT frequency domain spectral analysis digital signal processing
L_4_17 Credible Genetics & Origins

L_4_17 — Transgenerational Epigenetic Trauma

Transgenerational epigenetic inheritance of trauma — the hypothesis that severe stress, famine, or psychological trauma experienced by one generation can alter the epigenetic marks (DNA methylation, histone modifications

transgenerational epigenetics epigenetic inheritance trauma cortisol PTSD Holocaust survivors
L_2_08 Verified Genetics & Origins

L_2_08 — East Asian Genetics and Population History

East Asia — comprising China, Japan, Korea, Mongolia, Taiwan, and mainland Southeast Asia — is home to the largest human population concentration on Earth and harbors a complex genetic history shaped by major north-south

East Asian genetics Chinese population Japanese genetics Korean genetics Han Chinese Jomon
L_2_03 Verified Genetics & Origins

L_2_03 — Ancient African Genetics

Africa harbors the greatest human genetic diversity on Earth — a direct consequence of being the continent of human origin, where populations have accumulated genetic variation for ~300,000+ years. Modern African populat

African genetics ancient African DNA African population history Bantu expansion Khoisan genetics deep population structure
L_2_09 Verified Genetics & Origins

L_2_09 — Genetic History of the Americas: Clovis to Contact

The genetic history of the Americas — from the initial peopling of the New World to the devastating population collapse after European contact — is one of the most intensively studied and rapidly evolving areas of paleog

Americas Native American Beringia Clovis pre-Clovis Anzick
L_3_09 Verified Genetics & Origins

L_3_09 — HLA Diversity and Immune System Evolution

The Human Leukocyte Antigen (HLA) system — the human version of the Major Histocompatibility Complex (MHC) found in all jawed vertebrates — is the most polymorphic gene region in the entire human genome. Located on chrom

HLA MHC major histocompatibility complex immune diversity balancing selection antigen presentation
L_3_18 Verified Genetics & Origins

L_3_18 — Horizontal Gene Transfer in Eukaryotes

Horizontal gene transfer (HGT) — the movement of genetic material between organisms through mechanisms other than vertical parent-to-offspring inheritance — was long considered a predominantly prokaryotic phenomenon, cen

horizontal gene transfer lateral gene transfer HGT LGT eukaryotes introgression
L_5_01 Verified Genetics & Origins

L_5_01 — Human Microbiome and Co-Evolution

The human microbiome — the aggregate community of microorganisms (bacteria, archaea, fungi, viruses, protists) living on and within the human body — comprises roughly 38 trillion microbial cells (Sender et al., 2016, Cel

microbiome gut bacteria metagenomics holobiont dysbiosis Firmicutes
L_5_09 Verified Genetics & Origins

L_5_09 — Human Microbiome Co-Evolution: Ancient Gut Companions

The human microbiome — the trillions of bacteria, archaea, fungi, and viruses that inhabit our bodies, particularly the gastrointestinal tract — is not merely a passive inhabitant but a co-evolved partner that has shaped

microbiome gut bacteria co-evolution Helicobacter pylori human migration paleomicrobiology
L_5_11 Verified Genetics & Origins

L_5_11 — Genetics of Altitude Adaptation: Tibet, Andes, Ethiopia

High-altitude adaptation represents one of the most dramatic and best-studied examples of natural selection in contemporary human populations. More than 140 million people worldwide live at elevations above 2,500 meters,

altitude adaptation hypoxia EPAS1 EGLN1 HIF pathway hemoglobin
Y_4_08 Verified Altered States

Y_4_08 — Sleep Science — REM, NREM, and the Ancient Understanding of Sleep

Sleep science has undergone a revolution in the 21st century, fundamentally altering our understanding of why humans sleep. The landmark 2012 discovery of the glymphatic system by Maiken Nedergaard revealed that the brai

sleep REM NREM glymphatic system slow-wave sleep dreams
Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
Y_5_07 Verified Altered States

Y_5_07 — Phenomenology of Pain and Pain Modulation

Pain — defined by the International Association for the Study of Pain (IASP, revised 2020) as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissu

pain nociception pain modulation gate control theory Melzack Wall
Y_3_05 Credible Altered States

Y_3_05 — Contemplative Neuroscience

Contemplative neuroscience — the scientific study of meditation, contemplative practices, and their effects on brain, body, and behavior — has matured from a fringe topic into a rigorous interdisciplinary field over the

contemplative neuroscience meditation neuroscience mindfulness long-term meditators Dalai Lama Mind and Life Institute
Y_3_20 Credible Altered States

Y_3_20 — Enlightenment Neuroscience: Satori, Samadhi & Mystical States

Enlightenment — known as satori or kensho in Zen Buddhism, samadhi in Hindu yogic traditions, fana in Sufism, theosis in Eastern Orthodox Christianity, and unio mystica in the Western mystical tradition — refers to state

enlightenment satori samadhi mystical experience nondual awareness default mode network
Y_1_03 Credible Altered States

Y_1_03 — Classical Antiquity Entheogens Synthesis

This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The

entheogens psychedelics mystery religions Eleusinian Mysteries kykeon ergot
Y_1_02 Verified Altered States

Y_1_02 — Ergot, Sacred Pharmacology, and History

This document examines Ergot, Sacred Pharmacology, and History, a topic within the Consciousness research area. Key areas of investigation include Claviceps purpurea — Biology and Chemistry, Ergot Alkaloids — The Chemist

ergot Claviceps purpurea ergotamine LSA LSD Albert Hofmann
Y_1_09 Verified Altered States

Y_1_09 — Toxins, Venoms, and Altered States

Several animal toxins and plant poisons produce dramatic altered states of consciousness, and their use in ritual, medicine, and folklore constitutes a significant chapter in the relationship between humans and psychoact

toxin venom poison tetrodotoxin TTX pufferfish
Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine