Y_1_14 — Toad Venom: Bufo alvarius, 5-MeO-DMT, and Desert Sacrament

Toad venom — specifically the venom of the Sonoran Desert toad (Incilius alvarius, formerly Bufo alvarius) — contains 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), one of the most potent psychoactive tryptamines known, p

Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers

Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl

Y_1_15 — Micro-Dosing: Sub-Perceptual Psychedelic Use and Cognitive Effects

Micro-dosing — the practice of regularly consuming sub-perceptual doses (typically 1/10th to 1/20th of a standard recreational dose) of psychedelic substances, most commonly LSD (~10–20 micrograms) or psilocybin (~0.1–0.

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption

Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon

P_0_00 — Philosophy & Meaning: Section Summary

P_1_09 — Philosophy of Time

The philosophy of time addresses some of the deepest questions in metaphysics: Is time real or an illusion? Does the present moment have a special ontological status, or are past, present, and future equally real? Does t

P_1_00 — Metaphysics Mind: Subfolder Summary

P_2_08 — Transhumanism and Enhancement Ethics

Transhumanism is the philosophical and cultural movement advocating the use of technology to fundamentally enhance human capacities — cognitive, physical, emotional, and moral — beyond the limits set by biological evolut

ZE_3_00 — Bioethics Technology: Subfolder Summary

I_0_00 — UAP Disclosure: Section Summary

I_5_00 — Cultural Psychological Phenomena: Subfolder Summary