RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,692 results for "G protein" — page 148 of 185

Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
Y_4_19 Credible Altered States

Y_4_19 — Ritual-Induced Ecstasy

Ritual-induced ecstasy — altered states of consciousness produced through collective ceremonial practices including dance, chanting, drumming, fasting, pain ordeal, and rhythmic movement — is one of the oldest and most u

ritual ecstasy trance collective effervescence Durkheim sacred dance
Y_4_03 Verified Altered States

Y_4_03 — Shamanic Practices / Altered States Synthesis

Shamanic practices represent humanity's oldest spiritual technology, attested across every inhabited continent from at least 30,000 BCE (Upper Paleolithic cave art) to the present day. Despite vast cultural distances — g

shamanism altered states Mircea Eliade ecstasy trance soul journey
Y_5_06 Verified Altered States

Y_5_06 — Extreme Environments, Isolation, and Consciousness

Extreme environments and prolonged isolation produce distinctive altered states of consciousness — hallucinations, dissociation, time distortion, the sensation of an unseen companion, and profound shifts in self-identity

isolation extreme environments polar psychology space psychology solitary confinement solo sailing
Y_5_17 Speculative Altered States

Y_5_17 — Astral Projection Laboratory Research

Astral projection — the subjective experience of consciousness separating from the physical body and traveling independently — has been reported across virtually all human cultures throughout history, from ancient Egypti

astral projection out-of-body experience OBE Charles Tart Robert Monroe temporo-parietal junction
Y_2_08 Verified Altered States

Y_2_08 — Anesthesia, Consciousness, and Awareness

General anesthesia — the pharmacological induction of unconsciousness, amnesia, analgesia, and immobility — is one of the most profound alterations of consciousness that humans routinely produce, yet how anesthetics actu

anesthesia general anesthesia consciousness awareness under anesthesia anesthetic awareness ether
Y_3_19 Credible Altered States

Y_3_19 — Kundalini Scientific Research

Kundalini — described in Hindu and yogic traditions as a dormant spiritual energy coiled at the base of the spine that can be awakened through meditation, yoga, or spontaneously, rising through the chakra system to produ

kundalini kundalini awakening yoga energy shakti chakra
Y_3_05 Credible Altered States

Y_3_05 — Contemplative Neuroscience

Contemplative neuroscience — the scientific study of meditation, contemplative practices, and their effects on brain, body, and behavior — has matured from a fringe topic into a rigorous interdisciplinary field over the

contemplative neuroscience meditation neuroscience mindfulness long-term meditators Dalai Lama Mind and Life Institute
Y_3_04 Verified Altered States

Y_3_04 — Mystical Experience — Neuroscience of the Numinous

Mystical experiences — characterized by unity consciousness, noetic quality, ineffability, transcendence of time and space, and deep positive affect — have been reported across every known culture and religious tradition

mystical experience numinous William James Rudolf Otto peak experience neurotheology
Y_3_11 Verified Altered States

Y_3_11 — Biofeedback and Neurofeedback

Biofeedback is the process of using real-time monitoring of physiological signals — heart rate, muscle tension, skin conductance, brainwave patterns — to train voluntary control over processes normally considered involun

biofeedback neurofeedback EEG biofeedback brain-computer interface operant conditioning alpha training
Y_3_08 Credible Altered States

Y_3_08 — Breathwork and Holotropic States of Consciousness

Deliberate manipulation of breathing patterns to alter consciousness is among the oldest and most widespread human practices, documented in yogic pranayama (circa 500 BCE, Yoga Sutras of Patanjali), Tibetan tummo (inner-

breathwork holotropic breathwork Stanislav Grof hyperventilation respiratory alkalosis hypocapnia
Y_3_06 Credible Altered States

Y_3_06 — Awe, Wonder, and Transcendent Emotions

Awe — the emotional response to perceived vastness that requires accommodation (cognitive restructuring of existing mental schemas) — has emerged as a frontier topic in affective neuroscience, positive psychology, and ph

awe wonder transcendent emotion self-transcendence vastness accommodation
Y_1_17 Verified Altered States

Y_1_17 — Ketamine Therapy and Dissociative Medicine

Ketamine — a dissociative anesthetic synthesized by Calvin Stevens at Parke-Davis in 1962 and first used clinically by Edward Domino and Guenter Corssen in 1966 — has emerged as a revolutionary treatment for treatment-re

ketamine esketamine spravato depression treatment-resistant nmda-receptor
Y_1_05 Verified Altered States

Y_1_05 — Soma and Haoma — The Sacred Plant of Vedic and Avestan Ritual

Soma (Sanskrit: sóma) is the most celebrated sacred substance in the Vedic corpus — a pressed plant juice ritually offered to the gods and consumed by priests, praised in all 114 hymns of Rig Veda Mandala IX plus ~6 addi

Soma Haoma Rig Veda Mandala IX Avesta entheogen Amanita muscaria
Y_1_11 Verified Altered States

Y_1_11 — Ketamine: Dissociative Anesthetic and Consciousness Explorer

Ketamine is a dissociative anesthetic — first synthesized by Calvin Stevens in 1962 and introduced into clinical use by Edward Domino and Guenter Corssen (1966) — that has undergone a remarkable transformation from battl

ketamine dissociative anesthetic K-hole NMDA antagonist depression esketamine
Y_1_09 Verified Altered States

Y_1_09 — Toxins, Venoms, and Altered States

Several animal toxins and plant poisons produce dramatic altered states of consciousness, and their use in ritual, medicine, and folklore constitutes a significant chapter in the relationship between humans and psychoact

toxin venom poison tetrodotoxin TTX pufferfish
Y_1_21 Credible Altered States

Y_1_21 — Plant Medicine & Alkaloid Chemistry

Alkaloids — nitrogen-containing organic compounds produced by plants as secondary metabolites — constitute one of the most important classes of biologically active molecules in both medicine and human culture. Over 20,00

alkaloids ethnobotany plant medicine pharmacognosy morphine quinine
Y_1_20 Credible Altered States

Y_1_20 — Cannabis & Consciousness

Cannabis (Cannabis sativa) is the most widely used psychoactive substance in the world after alcohol and tobacco, consumed by an estimated 192 million people globally (2020, UNODC World Drug Report), and its effects on c

cannabis marijuana THC CBD endocannabinoid system anandamide
Y_1_18 Verified Altered States

Y_1_18 — Addiction Neurochemistry: Reward Circuits, Tolerance & Therapeutic Frontiers

Addiction — now formally termed substance use disorder (SUD, DSM-5) — is a chronic, relapsing brain disorder characterized by compulsive drug seeking despite harmful consequences, affecting approximately 35 million peopl

addiction neurochemistry dopamine-reward mesolimbic-pathway opioid-crisis tolerance-dependence
H_2_08 Verified Suppression & Thesis

H_2_08 — Textbook Bias and National History Narratives

History textbooks are among the most powerful instruments of national identity formation — and among the most systematically distorted sources of historical knowledge in any society. Every nation's textbooks tell a selec

textbook bias national narrative history education textbook controversy Loewen Lies My Teacher Told Me