RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

1,552 results for "Pit 2" — page 14 of 78

L_4_04 Credible Genetics & Origins

L_4_04 — Ancient Proteomics and Paleoproteomics

Paleoproteomics — the recovery and analysis of ancient proteins from archaeological and paleontological specimens — has emerged as a revolutionary complement to ancient DNA (aDNA), dramatically extending the temporal and

paleoproteomics ancient proteins collagen fingerprinting ZooMS mass spectrometry MALDI-TOF
L_4_09 Verified Genetics & Origins

L_4_09 — Selective Sweeps and Positive Selection in Humans

A selective sweep occurs when a beneficial allele rises rapidly in frequency under positive natural selection, carrying nearby linked variants along with it (genetic hitchhiking) and reducing genetic variation across the

selective sweep positive selection natural selection allele frequency hitchhiking extended haplotype homozygosity
L_4_08 Verified Genetics & Origins

L_4_08 — Genetic Genealogy and Forensic Genomics

Genetic genealogy — the use of DNA testing for genealogical purposes — has undergone an explosive expansion since the early 2000s, driven by direct-to-consumer (DTC) genetic testing companies (23andMe, AncestryDNA, MyHer

genetic genealogy forensic DNA DNA profiling STR SNP array direct-to-consumer genetic testing
L_3_16 Verified Genetics & Origins

L_3_16 — Genomic Imprinting & Evolutionary Conflict

Genomic imprinting — the epigenetic phenomenon in which a subset of genes (~100–200 in mammals) are expressed from only one parental allele, with the other allele silenced by DNA methylation and histone modification esta

genomic imprinting parent-of-origin expression epigenetics kinship theory parental conflict IGF2
L_3_06 Credible Genetics & Origins

L_3_06 — Genetics of Intelligence and Cognition

The genetics of intelligence — one of the most studied yet contentious areas in behavioral genetics — has established that cognitive ability, as measured by standardized tests, has a substantial heritable component (~50–

intelligence genetics cognitive ability IQ heritability GWAS intelligence polygenic score educational attainment
L_3_11 Verified Genetics & Origins

L_3_11 — Genetics of Taste and Dietary Adaptation

Taste perception — the ability to detect sweet, salty, sour, bitter, and umami (savory) stimuli — is mediated by genetically encoded receptor proteins whose variation across individuals and populations reflects evolution

taste genetics TAS2R_4_05 PTC PROP bitter taste umami
L_3_08 Verified Genetics & Origins

L_3_08 — Genetics of Skin, Hair, and Eye Color

Human pigmentation — skin, hair, and eye color — is one of the best-understood complex traits in human genetics, with a relatively modest number of genes explaining a large proportion of variation compared to most polyge

pigmentation genetics melanin eumelanin pheomelanin MC1R OCA2
L_5_10 Verified Genetics & Origins

L_5_10 — Neandertal Introgression: Which Genes and Why They Persisted

When modern humans (Homo sapiens) migrated out of Africa ~60,000-70,000 years ago and encountered Neanderthals (Homo neanderthalensis) in western Asia and Europe, the two species interbred — and the genetic legacy of tha

Neandertal introgression admixture adaptive introgression purifying selection immune genes
L_5_15 Verified Genetics & Origins

L_5_15 — Genetic Genealogy: DNA Ancestry Testing and Population History

Genetic genealogy — the use of DNA testing to determine relationships and ancestry — has revolutionized both personal genealogy and population genetics since the early 2000s. Three types of DNA analysis provide different

genetic genealogy DNA ancestry 23andMe haplogroup mtDNA Y-chromosome
L_5_03 Verified Genetics & Origins

L_5_03 — Pharmacogenomics and Ancestral Medicine

Pharmacogenomics — the study of how genetic variation influences individual responses to drugs — bridges genetics, pharmacology, and clinical medicine. Humans carry extensive polymorphism in genes encoding drug-metaboliz

pharmacogenomics CYP2D6 CYP2C_5_04 drug metabolism personalized medicine warfarin
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
Y_4_01 Verified Altered States

Y_4_01 — Lucid Dreaming Research

Lucid dreaming — being consciously aware that you are dreaming WHILE dreaming, and potentially controlling dream content — was scientifically verified in 1975-1981 through a breakthrough protocol: pre-arranged EYE SIGNAL

lucid dreaming dream consciousness REM sleep sleeping brain metacognition prefrontal cortex
Y_2_17 Verified Altered States

Y_2_17 — Barrier Gating and Altered States of Consciousness

Altered states of consciousness — produced by psychedelics, anesthetics, hypnagogic and hypnopompic transitions, near-death events, deep meditation, breathwork, and sensory deprivation — share a common functional signatu

altered states default mode network REBUS psychedelics ion channels blood-brain barrier
Y_3_07 Credible Altered States

Y_3_07 — Music, Consciousness, and Altered States

Music is one of the most powerful modulators of conscious experience available without pharmacological intervention. Neuroimaging reveals that music engages an extraordinarily distributed network: auditory cortex (superi

music cognition music neuroscience chills frisson musical emotion default mode network music auditory cortex
Y_1_13 Credible Altered States

Y_1_13 — Xenon Gas and Nitrous Oxide: Anesthetic Gases as Consciousness Probes

Nitrous oxide (N₂O — "laughing gas") and xenon (Xe — a noble gas) are two anesthetic gases that have served as remarkable probes of consciousness — revealing how the manipulation of a single molecule or atom can dissolve

nitrous oxide xenon gas laughing gas William James NMDA antagonist anesthetic
Y_1_06 Verified Altered States

Y_1_06 — Psychedelic Research — Modern Science and Ancient Entheogen Parallels

Psychedelic research has undergone a dramatic revival since ~2006, with major studies at Johns Hopkins, Imperial College London, NYU, and MAPS demonstrating the therapeutic potential of psilocybin, MDMA, and ayahuasca/DM

psychedelic entheogen psilocybin DMT ayahuasca LSD
Y_1_08 Verified Altered States

Y_1_08 — Cannabis: History, Ethnobotany, and Pharmacology

Cannabis (Cannabis sativa L.) is one of humanity's oldest cultivated plants, with a relationship spanning at least 12,000 years based on archaeological evidence. Its use as fiber (hemp), food (seeds), medicine, and psych

cannabis marijuana hemp THC CBD endocannabinoid system
Y_1_07 Credible Altered States

Y_1_07 — Ego Dissolution and Psychedelic Neuroscience

Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p

ego dissolution psychedelic neuroscience default mode network psilocybin LSD DMT
H_3_18 Credible Suppression & Thesis

H_3_18 — Digital Information Control and Algorithmic Censorship

The shift from print and broadcast media to digital platforms (c. 2000–present) has created new mechanisms of information control that differ fundamentally from historical censorship. Unlike state censorship, which remov

digital-censorship algorithmic-suppression content-moderation platform-power search-manipulation deplatforming
ZE_4_06 Verified Ethics & Applied Philosophy

ZE_4_06 — Ethics of Death and Dying

The ethics of death and dying encompasses philosophical questions about the nature and badness of death, moral debates about end-of-life decisions (euthanasia, assisted suicide, palliative care), and the definition of de

death dying euthanasia assisted suicide palliative care hospice