RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,692 results for "G protein" — page 134 of 185

Z_5_03 Verified Molecular Biology

Z_5_03 — Metabolomics: The Small-Molecule Landscape of Life

Metabolomics — the comprehensive study of all small-molecule metabolites (<~1,500 Da) present in a biological sample (cell, tissue, organ, biofluid, organism) — is the newest of the major "-omics" disciplines (after geno

metabolomics metabolome mass spectrometry NMR metabolic profile biomarker
Z_2_01 Verified Molecular Biology

Z_2_01 — HLA System & Archaic Immune Inheritance

The Human Leukocyte Antigen (HLA) system is the most polymorphic region of the human genome, encoding cell-surface proteins critical to adaptive immune function. Located on chromosome 6p21.3, the Major Histocompatibility

HLA human leukocyte antigen MHC major histocompatibility complex archaic introgression Denisovan
Z_1_02 Verified Molecular Biology

Z_1_02 — Human Chromosome 2 Fusion — Evidence of Primate Ancestry

Humans possess 46 chromosomes (23 pairs), while all other great apes — chimpanzees, gorillas, and orangutans — possess 48 chromosomes (24 pairs). This discrepancy was explained in the 1980s–1990s when molecular cytogenet

chromosome 2 chromosome fusion telomere-telomere ancestral chromosomes primate karyotype great ape
Z_1_21 Verified Molecular Biology

Z_1_21 — Riboswitches and RNA Thermometers

Riboswitches are structured RNA elements typically found in the 5' untranslated regions (5' UTRs) of bacterial messenger RNAs that directly sense and bind specific small-molecule metabolites — changing their three-dimens

riboswitch RNA thermometer aptamer gene regulation metabolite sensing mRNA structure
Z_1_10 Verified Molecular Biology

Z_1_10 — Chromosome Evolution and Karyotype

Karyotype — the number, size, and morphology of chromosomes in a cell — varies enormously across species, from n=1 in the ant Myrmecia pilosula to n=630 in the fern Ophioglossum reticulatum. Humans have 2n=46 (23 pairs),

chromosome evolution karyotype chromosome number Robertsonian translocation chromosome fusion human chromosome 2
Z_1_20 Credible Molecular Biology

Z_1_20 — RNA World Hypothesis

The RNA World hypothesis proposes that life on Earth passed through an early stage in which RNA molecules served as both the carriers of genetic information AND the catalysts of chemical reactions — performing the dual r

RNA world ribozyme self-replication origin of life ribonucleotide prebiotic chemistry
Z_4_06 Verified Molecular Biology

Z_4_06 — Psychedelic Neurochemistry: 5-HT2A, Tryptamines, and Molecular Mechanisms

Psychedelic neurochemistry — the molecular-level study of how psychedelic compounds alter brain function to produce their characteristic effects (visual hallucinations, synesthesia, ego dissolution, mystical-type experie

psychedelics 5-HT2A receptor serotonin tryptamines psilocybin LSD
Z_4_02 Verified Molecular Biology

Z_4_02 — Stem Cells and Pluripotency

Stem cells — defined by the dual capacity for self-renewal (division producing at least one daughter cell retaining stemness) and differentiation (specialization into distinct cell types) — are the foundational building

stem cell pluripotency embryonic stem cell induced pluripotent stem cell iPSC Yamanaka factors
Z_4_11 Verified Molecular Biology

Z_4_11 — The Cell Cycle: Division, Checkpoints, and Cancer

The cell cycle — the ordered series of events by which a cell grows, replicates its DNA, and divides into two daughter cells — is one of the most fundamental processes in biology and one of the most intensively studied i

cell cycle mitosis CDK cyclin checkpoint p53
Z_4_15 Verified Molecular Biology

Z_4_15 — Molecular Motors: Kinesin, Dynein, and Myosin

Molecular motors — protein machines that convert the chemical energy of ATP hydrolysis into directed mechanical work — are the engines of cellular life, responsible for transporting cargo within cells, driving cell divis

molecular motor kinesin dynein myosin ATP cytoskeleton
K_3_09 Credible Consciousness

K_3_09 — Minimal Consciousness and the Threshold of Sentience

Where does consciousness begin? This question — the problem of the threshold of sentience — is one of the most challenging in consciousness studies because it requires identifying what KIND of physical system is minimall

minimal consciousness sentience threshold consciousness markers biological consciousness single cell behavior bacterial cognition
K_3_14 Credible Consciousness

K_3_14 — Consciousness in Octopuses and Distributed Nervous Systems

Octopuses (Octopus vulgaris, O. bimaculoides, Abdopus aculeatus, and ~300 other species in order Octopoda) represent perhaps the most profound natural experiment in the evolution of consciousness: they are the most cogni

octopus cephalopod consciousness distributed nervous system invertebrate cognition mollusc
K_3_15 Verified Consciousness

K_3_15 — Anesthesia and the Mechanisms of Consciousness Loss

General anesthesia — the reversible abolition of consciousness through pharmacological agents — is one of the most remarkable phenomena in medicine: it routinely eliminates subjective experience in millions of patients d

anesthesia consciousness-loss general-anesthesia neural-correlates propofol sevoflurane
K_3_11 Verified Consciousness

K_3_11 — Animal Consciousness and Sentience

The question of whether non-human animals possess conscious experience — subjective awareness, felt pain, emotions, and self-recognition — has moved from philosophical speculation to a major neuroscientific research prog

animal consciousness sentience Cambridge Declaration mirror test Gallup pain perception
K_4_04 Speculative Consciousness

K_4_04 — Morphic Resonance and Sheldrake's Hypothesis

Morphic resonance is a hypothesis proposed by biologist Rupert Sheldrake (b. 1942, Cambridge-trained plant physiologist) that proposes nature operates by habits, not fixed laws, and that organisms and systems are influen

morphic resonance Rupert Sheldrake morphogenetic field formative causation habits of nature collective memory
K_4_15 Credible Consciousness

K_4_15 — Shared Death Experiences

Shared death experiences (SDEs) are reported phenomena in which a person who is physically healthy — typically a family member, caregiver, or bystander present at a death — describes experiencing some or all of the featu

shared death experience SDE near-death experience NDE deathbed vision empathic death
K_4_11 Verified Consciousness

K_4_11 — Collective Consciousness & the Collective Unconscious

Collective consciousness — whether framed as Durkheim's sociological construct, Jung's archetypal collective unconscious, or ancient concepts like the Akashic Records and the Noosphere — describes a shared psychic field

collective consciousness collective unconscious Jung Durkheim archetypes Global Consciousness Project
K_2_21 Verified Consciousness

K_2_21 — Transcranial Brain Stimulation: tDCS, TMS, and Deep Brain Stimulation

Transcranial brain stimulation encompasses a family of techniques that modulate neural activity by delivering energy — magnetic pulses, electrical current, or implanted electrodes — to specific brain regions. The three p

transcranial magnetic stimulation TMS transcranial direct current stimulation tDCS deep brain stimulation DBS
K_2_20 Verified Consciousness

K_2_20 — Savant Syndrome — Neuroscience of Extraordinary Ability

Savant syndrome — the coexistence of extraordinary ability in a specific domain with significant cognitive disability or neurodevelopmental condition — was first described medically by J. Langdon Down (the physician who

savant syndrome savant extraordinary ability autism intellectual disability prodigious savant
K_2_10 Verified Consciousness

K_2_10 — Neural Entrainment: External Rhythmic Brain Synchronization

Neural entrainment — the process by which rhythmic external stimuli (sound, light, tactile vibration, or electromagnetic fields) synchronize the timing of neural oscillations in the brain — is a well-established neurophy

neural entrainment brainwave entrainment auditory entrainment photic driving rhythmic stimulation neural oscillation