RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,279 results for "ion channel" — page 133 of 164

L_3_00 Genetics & Origins

L_3_00 — Adaptation Traits: Subfolder Summary

L_3_07 Credible Genetics & Origins

L_3_07 — Behavioral Genetics: Nature and Nurture

Behavioral genetics — the scientific study of how genetic and environmental factors contribute to individual differences in behavior — has transformed our understanding of human psychology over the past half-century. Thr

behavioral genetics nature nurture twin study heritability adoption study gene-environment interaction
L_5_04 Verified Genetics & Origins

L_5_04 — Ancient Microbiome and Paleomicrobiology

Paleomicrobiology — the study of ancient microorganisms through the application of molecular techniques (ancient DNA extraction, metagenomics, proteomics) to archaeological and paleontological material — has revolutioniz

microbiome paleomicrobiology ancient DNA aDNA dental calculus coprolite
Y_4_08 Verified Altered States

Y_4_08 — Sleep Science — REM, NREM, and the Ancient Understanding of Sleep

Sleep science has undergone a revolution in the 21st century, fundamentally altering our understanding of why humans sleep. The landmark 2012 discovery of the glymphatic system by Maiken Nedergaard revealed that the brai

sleep REM NREM glymphatic system slow-wave sleep dreams
Y_4_02 Verified Altered States

Y_4_02 — Savant Syndrome and Acquired Genius

Savant syndrome — extraordinary ability coexisting with significant cognitive disability — affects roughly 1 in 10 people with autism and ~1 in 2,000 people with other developmental disabilities or brain injuries. What m

savant syndrome acquired savant traumatic brain injury autistic savant Kim Peek Daniel Tammet
Y_4_01 Verified Altered States

Y_4_01 — Lucid Dreaming Research

Lucid dreaming — being consciously aware that you are dreaming WHILE dreaming, and potentially controlling dream content — was scientifically verified in 1975-1981 through a breakthrough protocol: pre-arranged EYE SIGNAL

lucid dreaming dream consciousness REM sleep sleeping brain metacognition prefrontal cortex
Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
Y_4_16 Verified Altered States

Y_4_16 — Hypnagogia: The Threshold State Between Waking and Sleep

Hypnagogia is the transitional state of consciousness experienced during the onset of sleep (waking-to-sleep), characterized by vivid spontaneous imagery, auditory hallucinations, distorted body perception, and loosened

hypnagogia hypnagogic hypnopompic sleep onset threshold consciousness tetris effect
Y_4_20 Credible Altered States

Y_4_20 — Drumming & Trance Neuroscience

Shamanic drumming — typically monotonous percussive rhythms at approximately 4–4.5 beats per second — has been used across virtually every indigenous culture as a primary technology for inducing trance states, and modern

drumming trance theta rhythm auditory driving EEG entrainment
Y_4_11 Credible Altered States

Y_4_11 — Trance States Across Cultures

Trance — an altered state of consciousness characterized by narrowed or shifted attention, altered sense of self, reduced awareness of external surroundings, and modified responsiveness — is one of the most universal fea

trance ritual trance cross-cultural trance possession trance shamanic trance altered states of consciousness
Y_4_10 Verified Altered States

Y_4_10 — Glossolalia, Xenoglossy, and Altered Language States

Glossolalia — commonly known as "speaking in tongues" — is a cross-cultural phenomenon in which individuals produce fluent, seemingly language-like vocalizations that do not correspond to any known natural language. Prac

glossolalia speaking in tongues xenoglossy Pentecostal Pythia Delphi
Y_4_03 Verified Altered States

Y_4_03 — Shamanic Practices / Altered States Synthesis

Shamanic practices represent humanity's oldest spiritual technology, attested across every inhabited continent from at least 30,000 BCE (Upper Paleolithic cave art) to the present day. Despite vast cultural distances — g

shamanism altered states Mircea Eliade ecstasy trance soul journey
Y_4_21 Credible Altered States

Y_4_21 — Fasting-Induced Altered States

Fasting-induced altered states of consciousness — visionary experiences, euphoria, time distortion, dissociation, and mystical-type experiences produced by prolonged food deprivation — represent one of humanity's oldest

fasting altered states ketosis beta-hydroxybutyrate vision quest asceticism
Y_5_03 Verified Altered States

Y_5_03 — Pineal Gland / Third Eye Across Cultures

The pineal gland sits at the geometric center of the brain and has been called "the third eye" across cultures for millennia. Ancient pine cone motifs appear at the Vatican (Cortile della Pigna), Assyrian reliefs (winged

pineal gland third eye pine cone ajna chakra Eye of Horus DMT
Y_5_02 Verified Altered States

Y_5_02 — CIA Gateway Process, Monroe Institute & Hemi-Sync

The CIA's Gateway Process Analysis Report (1983) is a declassified U.S. Army Intelligence document that evaluated the Monroe Institute's Hemi-Sync technology for potential military/intelligence applications. Written by L

Gateway Process Gateway Experience Monroe Institute Hemi-Sync binaural beats Robert Monroe
Y_5_20 Verified Altered States

Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks

MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w

MDMA ecstasy entactogen empathogen serotonin PTSD therapy
Y_5_01 Verified Altered States

Y_5_01 — Remote Viewing & Psychic Programs

The U.S. government spent $20M+ over 23 years (1972–1995) investigating psychic phenomena under classified programs known collectively as "Stargate." Research was published in Nature (1974) and IEEE (1976). The program p

remote viewing Stargate SRI CIA DIA Targ
Y_5_04 Credible Altered States

Y_5_04 — Anomalous Human Abilities — Yogic Siddhis, Firewalking, and Extreme Performance

Human cultures have long documented individuals who demonstrate extraordinary physical and mental abilities that challenge conventional understanding of human limits. This document surveys the full spectrum, from well-do

siddhis firewalking Wim Hof tummo breatharianism extreme fasting
Y_0_00 Altered States

Y_0_00 — Altered States & Psychedelics: Section Summary

Y_2_05 Credible Altered States

Y_2_05 — Near-Death Experiences: Cross-Cultural Analysis

Near-death experiences (NDEs) — profound subjective experiences occurring during clinical death, cardiac arrest, or perceived proximity to death — have been reported across virtually all cultures and historical periods.

near-death experience NDE cross-cultural NDE tunnel experience life review being of light out-of-body experience