RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

2,397 results for "System 1" — page 13 of 120

L_4_01 Verified Genetics & Origins

L_4_01 — Ancient DNA from Sediment — Environmental DNA Revolution

Environmental DNA (eDNA) recovery from sediments has revolutionized our ability to detect the presence of organisms — including ancient humans — without requiring the discovery of any bones, teeth, or artifacts. The land

environmental DNA eDNA sediment DNA Denisova Cave permafrost DNA metagenomic sequencing
L_4_10 Verified Genetics & Origins

L_4_10 — Sex Chromosome Evolution

Sex chromosomes — the genetic elements that determine biological sex in many organisms — represent one of the most remarkable stories in genome evolution. In mammals, the XX/XY system prevails: females have two X chromos

sex chromosome X chromosome Y chromosome sex determination SRY dosage compensation
L_2_17 Verified Genetics & Origins

L_2_17 — Pacific Islander Genetics: Austronesian Ancestry, Denisovan Introgression, and Oceanian Genomics

Pacific Islander populations — spanning Melanesia, Micronesia, and Polynesia — harbor some of the most genetically complex and scientifically informative genomes in human biology. Their genetic history records multiple d

Pacific Islander genetics Oceanian genomics Denisovan introgression Polynesian motif Austronesian ancestry Melanesian genetics
L_3_16 Verified Genetics & Origins

L_3_16 — Genomic Imprinting & Evolutionary Conflict

Genomic imprinting — the epigenetic phenomenon in which a subset of genes (~100–200 in mammals) are expressed from only one parental allele, with the other allele silenced by DNA methylation and histone modification esta

genomic imprinting parent-of-origin expression epigenetics kinship theory parental conflict IGF2
L_3_13 Verified Genetics & Origins

L_3_13 — Human Accelerated Regions: What Makes Us Genetically Unique

Human Accelerated Regions (HARs) are short segments of the genome that were highly conserved across millions of years of mammalian evolution — indicating strong functional constraint — but then underwent a burst of rapid

human accelerated regions HARs HAR1 HACNS1 conserved noncoding enhancer
L_3_05 Verified Genetics & Origins

L_3_05 — Blood Type Genetics and the ABO System

Blood group genetics represents one of the earliest and most clinically important applications of Mendelian inheritance in human biology. Karl Landsteiner's discovery of the ABO blood group system (1900–1901) — which ear

blood type ABO system Rh factor Karl Landsteiner blood transfusion blood group antigens
L_3_11 Verified Genetics & Origins

L_3_11 — Genetics of Taste and Dietary Adaptation

Taste perception — the ability to detect sweet, salty, sour, bitter, and umami (savory) stimuli — is mediated by genetically encoded receptor proteins whose variation across individuals and populations reflects evolution

taste genetics TAS2R_4_05 PTC PROP bitter taste umami
L_3_12 Verified Genetics & Origins

L_3_12 — Genetics of Pigmentation: Skin, Hair, and Eye Color Evolution

Human pigmentation — the variation in skin, hair, and eye color across populations — is one of the most visible and best-understood examples of natural selection in our species. Pigmentation is determined primarily by th

pigmentation melanin skin color SLC24A5 SLC45A2 MC1R
L_5_10 Verified Genetics & Origins

L_5_10 — Neandertal Introgression: Which Genes and Why They Persisted

When modern humans (Homo sapiens) migrated out of Africa ~60,000-70,000 years ago and encountered Neanderthals (Homo neanderthalensis) in western Asia and Europe, the two species interbred — and the genetic legacy of tha

Neandertal introgression admixture adaptive introgression purifying selection immune genes
L_5_13 Credible Genetics & Origins

L_5_13 — The Microbiome-Brain Axis: Gut Bacteria, Mood & Consciousness

The microbiome-gut-brain axis — bidirectional communication between the trillions of gut microorganisms and the central nervous system — has emerged as one of the most significant frontiers in neuroscience and consciousn

microbiome-brain-axis gut-brain-axis psychobiome vagus-nerve microbial-metabolites serotonin-gut
Y_4_01 Verified Altered States

Y_4_01 — Lucid Dreaming Research

Lucid dreaming — being consciously aware that you are dreaming WHILE dreaming, and potentially controlling dream content — was scientifically verified in 1975-1981 through a breakthrough protocol: pre-arranged EYE SIGNAL

lucid dreaming dream consciousness REM sleep sleeping brain metacognition prefrontal cortex
Y_4_16 Verified Altered States

Y_4_16 — Hypnagogia: The Threshold State Between Waking and Sleep

Hypnagogia is the transitional state of consciousness experienced during the onset of sleep (waking-to-sleep), characterized by vivid spontaneous imagery, auditory hallucinations, distorted body perception, and loosened

hypnagogia hypnagogic hypnopompic sleep onset threshold consciousness tetris effect
Y_4_11 Credible Altered States

Y_4_11 — Trance States Across Cultures

Trance — an altered state of consciousness characterized by narrowed or shifted attention, altered sense of self, reduced awareness of external surroundings, and modified responsiveness — is one of the most universal fea

trance ritual trance cross-cultural trance possession trance shamanic trance altered states of consciousness
Y_5_19 Verified Altered States

Y_5_19 — Congenital Insensitivity to Pain: SCN9A, Nociception, and the Neuroscience of Painlessness

Congenital insensitivity to pain (CIP) encompasses a group of rare inherited conditions in which individuals are born with absent or severely diminished pain perception while retaining other sensory modalities (touch, pr

congenital insensitivity to pain CIP CIPA SCN9A Nav1.7 nociception
Y_2_15 Credible Altered States

Y_2_15 — Breathwork Traditions: Holotropic, Tummo, and Physiological Extremes

Breathwork — the deliberate manipulation of breathing patterns to induce altered physiological and psychological states — represents one of humanity's oldest and most accessible methods for modifying consciousness, with

breathwork holotropic-breathing tummo wim-hof-method pranayama hyperventilation
Y_3_01 Verified Altered States

Y_3_01 — Kundalini and Serpent Energy Traditions

Kundalini ("coiled one" in Sanskrit) describes a dormant serpent-like energy said to reside at the base of the spine, which, when "awakened" through meditation, breathwork, or spontaneous experience, rises through a cent

kundalini serpent energy chakras nadis subtle body yoga
Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine
Y_1_16 Verified Altered States

Y_1_16 — Psychedelic Legal Frameworks: Regulation, Decriminalization, and Therapeutic Access

The legal status of psychedelic substances — including psilocybin, LSD, MDMA, DMT/ayahuasca, mescaline, and ibogaine — has undergone dramatic shifts since the mid-20th century, moving from unregulated research compounds

psychedelic law psilocybin MDMA Schedule I decriminalization right to try
H_2_18 Credible Suppression & Thesis

H_2_18 — Cold War Scientific Espionage and Suppressed Research

The Cold War (1947–1991) created an unprecedented regime of scientific secrecy in which entire fields of research — nuclear physics, rocketry, biological weapons, cryptography, remote sensing, and materials science — wer

cold-war-science operation-paperclip scientific-espionage classified-research nuclear-secrecy soviet-science
H_2_14 Verified Suppression & Thesis

H_2_14 — Funding Bias in Science: Who Pays, Who Decides, What Gets Studied

Scientific research is shaped not only by curiosity and methodology but by who funds it — and funders' priorities, interests, and incentive structures systematically influence what questions get asked, what methods are u

funding bias research agenda corporate science grant system NIH NSF