RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

3,669 results for "Y chromosome" — page 119 of 184

Z_4_18 Verified Molecular Biology

Z_4_18 — Protein Misfolding and Prion Diseases

Prion diseases — transmissible spongiform encephalopathies (TSEs) — are fatal neurodegenerative disorders caused by the misfolding and self-propagating aggregation of a normal cellular protein (PrPᶜ) into a pathological

prion protein-misfolding amyloid bse cjd mad-cow-disease
Z_4_10 Verified Molecular Biology

Z_4_10 — Signal Transduction: How Cells Communicate

Signal transduction — the molecular mechanisms by which cells detect, interpret, and respond to external signals (hormones, growth factors, neurotransmitters, cytokines, environmental cues) — is one of the central organi

signal transduction cell signaling receptor kinase second messenger G protein
Z_4_19 Verified Molecular Biology

Z_4_19 — Exosome Signaling and Intercellular Communication

Exosomes are small (30–150 nm) membrane-bound extracellular vesicles (EVs) released by virtually all cell types, carrying a cargo of proteins, lipids, mRNAs, microRNAs (miRNAs), and other nucleic acids that can be taken

exosome extracellular vesicle intercellular communication microRNA mRNA transfer multivesicular body
K_3_09 Credible Consciousness

K_3_09 — Minimal Consciousness and the Threshold of Sentience

Where does consciousness begin? This question — the problem of the threshold of sentience — is one of the most challenging in consciousness studies because it requires identifying what KIND of physical system is minimall

minimal consciousness sentience threshold consciousness markers biological consciousness single cell behavior bacterial cognition
K_3_02 Credible Consciousness

K_3_02 — Embodied Cognition

Embodied cognition is a broad research program challenging the classical cognitive science view that the mind is essentially a computer processing abstract symbols in the brain. Instead, embodied cognition holds that thi

embodied cognition 4E cognition embedded enacted extended embodied
K_3_05 Credible Consciousness

K_3_05 — Extended Mind and Cognitive Extension

The extended mind thesis (EMT), proposed by Andy Clark and David Chalmers in their landmark 1998 paper "The Extended Mind," argues that cognitive processes need not be confined within the skull — external objects, tools,

extended mind cognitive extension Clark and Chalmers parity principle Otto's notebook scaffolded cognition
K_3_16 Verified Consciousness

K_3_16 — Anesthesia and Consciousness: What Going Under Reveals

General anesthesia provides a unique experimental window into consciousness: the ability to reversibly abolish and restore awareness in a controlled clinical setting. Despite over 175 years of practice since William T.G.

anesthesia-consciousness general-anesthesia propofol ketamine sevoflurane awareness-under-anesthesia
K_1_13 Credible Consciousness

K_1_13 — Enactivism: Consciousness Through Action and Interaction

Enactivism is a radical approach to cognition and consciousness that rejects the traditional computational model of the mind (the brain as information-processing computer operating on internal representations of the exte

enactivism embodied cognition autopoiesis sense-making Varela Thompson
K_1_01 Credible Consciousness

K_1_01 — Quantum Consciousness & Penrose-Hameroff

The Orchestrated Objective Reduction (Orch-OR) theory — proposed by Nobel laureate Roger Penrose and anesthesiologist Stuart Hameroff — suggests consciousness arises from quantum computations in microtubules within neuro

Orch-OR orchestrated objective reduction Penrose Hameroff microtubules quantum consciousness
K_1_14 Credible Consciousness

K_1_14 — Qualia: The Subjective Experience Problem

Qualia (singular: quale) — the term used in philosophy of mind for the subjective, experiential properties of conscious mental states — the redness of red, the painfulness of pain, the taste of coffee, the felt quality o

qualia subjective experience hard problem phenomenal consciousness Mary's Room what-it-is-like
K_4_13 Verified Consciousness

K_4_13 — Mirror Neurons and Social Cognition

Mirror neurons are a class of neurons, first discovered in the early 1990s in the premotor cortex (area F5) of macaque monkeys by Giacomo Rizzolatti, Vittorio Gallese, and colleagues at the University of Parma, that fire

mirror neuron social cognition empathy imitation action understanding premotor cortex
K_4_18 Verified Consciousness

K_4_18 — Near-Death Experiences: Evidence, Neuroscience, and the Consciousness Debate

Near-death experiences (NDEs) are complex subjective experiences reported by approximately 10–20% of cardiac arrest survivors, characterized by feelings of peace, tunnel vision, life review, encounters with deceased pers

near-death experience NDE cardiac arrest consciousness out-of-body AWARE study
K_4_01 Verified Consciousness

K_4_01 — Shamanism, Entheogens & Serpent Visions

Shamanism as a cross-cultural altered-state practice is Tier 1 anthropology (Eliade 1964, Winkelman 2010). Clinical psilocybin and DMT research is Tier 1 (Griffiths 2006/2019, Strassman 2001, Davis 2021). The consistent

shamanism DMT ayahuasca psilocybin Strassman Harner
K_4_15 Credible Consciousness

K_4_15 — Shared Death Experiences

Shared death experiences (SDEs) are reported phenomena in which a person who is physically healthy — typically a family member, caregiver, or bystander present at a death — describes experiencing some or all of the featu

shared death experience SDE near-death experience NDE deathbed vision empathic death
K_4_11 Verified Consciousness

K_4_11 — Collective Consciousness & the Collective Unconscious

Collective consciousness — whether framed as Durkheim's sociological construct, Jung's archetypal collective unconscious, or ancient concepts like the Akashic Records and the Noosphere — describes a shared psychic field

collective consciousness collective unconscious Jung Durkheim archetypes Global Consciousness Project
K_2_05 Credible Consciousness

K_2_05 — Unconscious Processing

The cognitive unconscious — mental processes that influence behavior, emotion, and decision-making without reaching conscious awareness — is one of the most empirically robust phenomena in psychology and neuroscience. Fa

unconscious processing subliminal perception implicit memory priming blindsight automatic processing
K_2_17 Verified Consciousness

K_2_17 — Brain-Computer Interfaces: Neural Engineering, Neuroprosthetics, and the Brain-Machine Frontier

Brain-computer interfaces (BCIs) are systems that establish a direct communication pathway between the brain's electrical activity and external devices, bypassing normal neuromuscular channels. The concept was formalized

brain-computer interface BCI neuroprosthesis Utah Array BrainGate Neuralink
K_2_21 Verified Consciousness

K_2_21 — Transcranial Brain Stimulation: tDCS, TMS, and Deep Brain Stimulation

Transcranial brain stimulation encompasses a family of techniques that modulate neural activity by delivering energy — magnetic pulses, electrical current, or implanted electrodes — to specific brain regions. The three p

transcranial magnetic stimulation TMS transcranial direct current stimulation tDCS deep brain stimulation DBS
K_2_06 Credible Consciousness

K_2_06 — Neurofeedback and Brain Training

Neurofeedback — the real-time display of brain activity (typically EEG) to enable individuals to learn self-regulation of neural dynamics through operant conditioning — has been investigated since the pioneering work of

neurofeedback EEG biofeedback brain training operant conditioning EEG SMR training alpha-theta training
K_2_16 Verified Consciousness

K_2_16 — Optogenetics: Light-Controlled Neural Circuits

Optogenetics is a biological technique that uses genetically encoded light-sensitive proteins (opsins) to control the activity of specific neurons with millisecond precision using light. Developed primarily by Karl Deiss

optogenetics channelrhodopsin halorhodopsin archaerhodopsin ChR2 opsins