RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
3,279 results for "ion channel" — page 110 of 164
K_3_15 — Anesthesia and the Mechanisms of Consciousness Loss
General anesthesia — the reversible abolition of consciousness through pharmacological agents — is one of the most remarkable phenomena in medicine: it routinely eliminates subjective experience in millions of patients d
K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects
The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica
K_3_04 — Anesthesia and Consciousness
General anesthesia — the reversible, drug-induced abolition of consciousness — is one of medicine's greatest achievements and, paradoxically, one of its least understood. Approximately 350 million surgical procedures per
K_3_03 — Memory and Consciousness
Memory and consciousness are deeply intertwined — memory provides the continuity of experience that creates a sense of self persisting through time, while consciousness provides the subjective context within which memori
K_1_03 — Free Energy Principle and Predictive Processing
The Free Energy Principle (FEP), developed by neuroscientist Karl Friston (2006-present), is one of the most ambitious theoretical frameworks in 21st-century science: it attempts to explain the EXISTENCE, BEHAVIOR, and C
K_1_06 — Predictive Processing and Consciousness
Predictive processing (PP) is a unifying framework in cognitive neuroscience proposing that the brain is fundamentally a prediction machine — it continuously generates top-down predictions of incoming sensory input and u
K_1_11 — Dualism: Mind-Body Problem Across Philosophy and Neuroscience
The mind-body problem — the question of how subjective mental experience (consciousness, thought, sensation, emotion) relates to the physical body (brain, nervous system, matter) — is arguably the oldest and most persist
K_1_04 — Brain as Filter vs Generator
Two opposing models have dominated the consciousness debate for over a century:
K_1_02 — Biocentrism and Observer-Dependent Reality
Biocentrism, proposed by Robert Lanza (stem cell biologist) and Bob Berman (astronomer) in 2009, argues that consciousness is FUNDAMENTAL to the universe — not an accidental byproduct of matter — and that the universe's
K_1_05 — Global Workspace Theory
Global Workspace Theory (GWT), proposed by Bernard Baars (1988) and neurally formalized by Stanislas Dehaene and Jean-Pierre Changeux as the Global Neuronal Workspace (GNW, 1998–2011), is one of the leading scientific th
K_1_01 — Quantum Consciousness & Penrose-Hameroff
The Orchestrated Objective Reduction (Orch-OR) theory — proposed by Nobel laureate Roger Penrose and anesthesiologist Stuart Hameroff — suggests consciousness arises from quantum computations in microtubules within neuro
K_1_10 — Panpsychism — Comprehensive Survey
Panpsychism — the view that consciousness or experiential properties are fundamental and ubiquitous features of the physical world — has experienced a dramatic revival in analytic philosophy since the early 2000s, driven
K_1_15 — Consciousness–Genetics Interface
Genetic variation significantly modulates conscious experience, including baseline personality, susceptibility to altered states, response to psychoactive substances, meditation capacity, and vulnerability to disorders o
K_1_08 — Higher-Order Theories of Consciousness
Higher-order (HO) theories of consciousness propose that a mental state becomes conscious not by virtue of its intrinsic properties but because it is the target of a higher-order mental representation — a thought, percep
K_1_09 — Philosophical Zombies and the Hard Problem
The philosophical zombie (p-zombie) thought experiment, formalized by David Chalmers (1996), asks: Could there exist a being physically and functionally identical to a conscious human — identical atom for atom, processin
K_1_14 — Qualia: The Subjective Experience Problem
Qualia (singular: quale) — the term used in philosophy of mind for the subjective, experiential properties of conscious mental states — the redness of red, the painfulness of pain, the taste of coffee, the felt quality o
K_4_18 — Near-Death Experiences: Evidence, Neuroscience, and the Consciousness Debate
Near-death experiences (NDEs) are complex subjective experiences reported by approximately 10–20% of cardiac arrest survivors, characterized by feelings of peace, tunnel vision, life review, encounters with deceased pers
K_4_02 — Stigmata, Faith Healing, and Psychosomatic Phenomena
The human body can do things under the influence of belief that should not be physically possible according to conventional medical models. The placebo effect — a "sugar pill" producing measurable physiological changes —
K_4_15 — Shared Death Experiences
Shared death experiences (SDEs) are reported phenomena in which a person who is physically healthy — typically a family member, caregiver, or bystander present at a death — describes experiencing some or all of the featu
K_4_08 — Parapsychology — Experimental Research on Psi Phenomena
Parapsychology is the scientific study of purported psychic phenomena — telepathy, clairvoyance, precognition, and psychokinesis (collectively termed "psi") — using experimental methods. Originating with J.B. Rhine's car
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