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Search 3,717 documents across 34 fields — every claim tier-rated by evidence

3,717 documents 34 sections 47,686 citations 34,596+ keywords indexed 4 evidence tiers

296 results for "guide RNA" — page 11 of 15

Y_1_09 Verified Altered States

Y_1_09 — Toxins, Venoms, and Altered States

Several animal toxins and plant poisons produce dramatic altered states of consciousness, and their use in ritual, medicine, and folklore constitutes a significant chapter in the relationship between humans and psychoact

toxin venom poison tetrodotoxin TTX pufferfish
Y_1_19 Credible Altered States

Y_1_19 — Ibogaine Reset Mechanism

Ibogaine — a naturally occurring psychoactive indole alkaloid extracted from the root bark of Tabernanthe iboga, a shrub native to the equatorial forests of Gabon and Cameroon — has emerged as one of the most pharmacolog

ibogaine iboga Tabernanthe iboga addiction opioid noribogaine
Y_1_10 Credible Altered States

Y_1_10 — Ibogaine: African Plant Medicine and Addiction Interruption

Ibogaine is a naturally occurring psychoactive indole alkaloid derived from the root bark of the West African shrub Tabernanthe iboga, which has been used for centuries in the Bwiti spiritual tradition of Gabon, Cameroon

ibogaine iboga Tabernanthe iboga Bwiti addiction interruption opioid withdrawal
H_2_12 Verified Suppression & Thesis

H_2_12 — Peer Review: History, Flaws, and Gatekeeping Function

Peer review — the evaluation of scientific manuscripts by expert reviewers before publication — is the primary mechanism by which the scientific community certifies knowledge claims as meeting disciplinary standards of e

peer review publishing gatekeeping quality control bias anonymity
H_3_01 Suppression & Thesis

H_3_01 — Indigenous Knowledge Suppression — Colonialism and Epistemicide

Epistemicide — the systematic destruction of rival knowledge systems — is arguably the most devastating and least acknowledged consequence of global colonialism. Between 1492 and 1950, European colonial powers destroyed,

epistemicide indigenous knowledge colonialism imperialism cultural suppression residential schools
H_4_29 Verified Suppression & Thesis

H_4_29 — Food Industry Science Suppression

The systematic influence of the food industry on nutrition science, dietary guidelines, and public health policy represents one of the most extensively documented cases of corporate science suppression in the modern era

food industry sugar manufactured doubt tobacco playbook nutrition science lobbying
H_4_05 Suppression & Thesis

H_4_05 — Digital Age Censorship and Algorithm Suppression

The digital age has introduced unprecedented mechanisms for information suppression, censorship, and narrative control that operate at global scale and often remain invisible to those affected. This document examines thr

Great Firewall internet censorship algorithmic suppression content moderation deplatforming social media censorship
H_4_04 Suppression & Thesis

H_4_04 — Soviet Science Suppression — Lysenkoism and Vavilov

The Lysenko affair (1928–1964) represents the most devastating case of ideological suppression of science in the 20th century. Trofim Denisovich Lysenko (1898–1976), an agronomist with minimal formal training, rose to do

Lysenko Lysenkoism Vavilov Soviet genetics ideological science Lamarckism
H_4_17 Verified Suppression & Thesis

H_4_17 — Algorithmic Censorship and AI Content Moderation

Algorithmic content moderation — the use of automated systems (machine learning classifiers, natural language processing, computer vision, and large language models) to detect, flag, restrict, or remove online content —

algorithmic censorship content moderation AI moderation platform governance shadow ban demonetization
H_4_27 Verified Suppression & Thesis

H_4_27 — Open Access and Democratization of Knowledge: Breaking the Paywalls

The modern academic publishing system creates a paradox: publicly funded research — produced by researchers paid by taxpayers, conducted in publicly funded institutions, peer-reviewed by unpaid volunteer referees — is ov

open access paywall academic publishing Elsevier Sci-Hub preprint
H_4_01 Suppression & Thesis

H_4_01 — Propaganda, Information Control, and the Manufacture of Consent

The systematic manipulation of public belief is as old as civilization itself. Egyptian pharaohs chiseled out predecessors' names (damnatio memoriae), Roman emperors staged bread and circuses, and Chinese imperial histor

propaganda censorship information control manufacture of consent Edward Bernays Noam Chomsky
H_4_32 Verified Suppression & Thesis

H_4_32 — Information Warfare, Propaganda & Manufactured Consent

Information warfare — the deliberate use of information and communication systems to gain strategic advantage — is as old as organized conflict, but the modern era has industrialized it. From Edward Bernays's founding of

propaganda information warfare manufactured consent Edward Bernays Chomsky psyops
P_3_10 Philosophy & Meaning

P_3_10 — Skepticism and Pyrrhonism

Skepticism — the philosophical position that knowledge is uncertain, limited, or impossible — is one of the oldest and most persistent currents in philosophy. Ancient Pyrrhonian skepticism (Pyrrho, ~360–270 BCE; Sextus E

skepticism Pyrrhonism Pyrrho Sextus Empiricus Academic skepticism Arcesilaus
P_3_09 Philosophy & Meaning

P_3_09 — Nihilism, Absurdism, and Camus

Nihilism — from Latin nihil ("nothing") — is the philosophical position that life, existence, and values lack objective meaning, purpose, or intrinsic worth. It is not a single doctrine but a cluster of related positions

nihilism absurdism Albert Camus Friedrich Nietzsche Myth of Sisyphus absurd
P_4_01 Philosophy & Meaning

P_4_01 — Death and the Afterlife Across Cultures

Every known human culture has developed beliefs about what happens after death — making afterlife cosmology one of the most universal features of human thought. The major frameworks include: judgment and reward/punishmen

death afterlife resurrection reincarnation ancestor worship near-death experience
P_1_09 Verified Philosophy & Meaning

P_1_09 — Philosophy of Time

The philosophy of time addresses some of the deepest questions in metaphysics: Is time real or an illusion? Does the present moment have a special ontological status, or are past, present, and future equally real? Does t

philosophy of time McTaggart A-series B-series presentism eternalism
P_1_18 Credible Philosophy & Meaning

P_1_18 — Process Philosophy: Whitehead, Event Ontology & Becoming

Process philosophy — the metaphysical tradition holding that reality is fundamentally constituted by processes, events, and becoming rather than by static substances or enduring matter — reaches its most systematic expre

process-philosophy alfred-north-whitehead event-ontology actual-occasions process-and-reality prehension
P_5_04 Philosophy & Meaning

P_5_04 — Process Philosophy — Whitehead and the Metaphysics of Becoming

Process philosophy, most fully developed in Alfred North Whitehead's Process and Reality (1929), proposes that reality is fundamentally constituted not by enduring substances but by dynamic events — "actual occasions of

process philosophy Alfred North Whitehead Process and Reality actual occasions prehension eternal objects
P_2_09 Verified Philosophy & Meaning

P_2_09 — Cosmopolitanism and Global Ethics

Cosmopolitanism — from the Greek kosmopolitēs ("citizen of the world") — is the philosophical tradition asserting that all human beings belong to a single moral community regardless of nationality, ethnicity, or culture.

cosmopolitanism global ethics global justice world citizen Kant perpetual peace
ZE_5_12 Verified Ethics & Applied Philosophy

ZE_5_12 — Ethics of Children: Rights, Development, and Moral Status

The ethics of children addresses a fundamental puzzle: children are full human beings deserving of moral respect, yet they lack the autonomy, rationality, and experience that ground many standard moral and political righ

children's rights child ethics moral status paternalism autonomy development