RESEARCH BASE
Search 3,717 documents across 34 fields — every claim tier-rated by evidence
27 results for "small molecules" — page 1 of 2
Z_5_03 — Metabolomics: The Small-Molecule Landscape of Life
Metabolomics — the comprehensive study of all small-molecule metabolites (<~1,500 Da) present in a biological sample (cell, tissue, organ, biofluid, organism) — is the newest of the major "-omics" disciplines (after geno
Z_3_03 — Ancient Pathogen Genomics — Plague, TB, Smallpox DNA
Ancient pathogen genomics — the recovery and sequencing of disease-causing organism DNA from archaeological remains — has revolutionized understanding of human disease history. Beginning with the landmark reconstruction
ZD_4_13 — Network Science: Graph Theory, Small Worlds, and Scale-Free Networks
Network science is the study of complex systems represented as networks (graphs) — collections of nodes (vertices) connected by edges (links) — encompassing social networks (people connected by friendships, collaboration
ZD_4_11 — Social Network Analysis — Granovetter, Small Worlds, Influence
Social network analysis (SNA) — the study of social structures through the use of graph theory and network science, where individuals (or organizations, nations, etc.) are represented as nodes and their relationships (fr
X_5_29 — Epidemiology and Pandemics: Disease, Civilization, and the Biology of Outbreaks
Epidemiology — the study of disease distribution and determinants in populations — has fundamentally shaped human history, often more decisively than warfare or politics. The Antonine Plague (165–180 CE, likely smallpox)
X_3_20 — Infectious Disease & Epidemiology
Infectious diseases have shaped human history more profoundly than any other biological force. The germ theory of disease, established by Louis Pasteur and Robert Koch in the 1860s–1880s, transformed medicine from specul
X_3_03 — Epidemic and Pandemic History
Epidemics and pandemics — the outbreak and widespread transmission of infectious disease — have shaped human civilization as profoundly as wars, technologies, and ideas. Ancient: the Plague of Athens (430 BCE, described
X_3_02 — Vaccination and Immunology History
Vaccination — the deliberate stimulation of adaptive immune responses using weakened, killed, or component pathogens to provide protection against infectious disease — is among the most consequential medical intervention
Z_4_04 — RNA Biology: Types and Functions
RNA (ribonucleic acid) — once considered merely a passive intermediary between DNA and protein — is now recognized as the most functionally diverse class of biological macromolecules, performing roles in catalysis, gene
ZB_5_02 — Biological Networks and Systems Biology
Systems biology investigates how biological function emerges from the collective interactions of molecular components — genes, proteins, metabolites, and signaling molecules — organized into networks. Rather than studyin
G_3_05 — Self-Organization and Emergence
Self-organization is the process by which global order arises from local interactions among components of an initially disordered system, without external direction or centralized control. Emergence is the closely relate
G_3_27 — Morphic Resonance vs Epigenetic Inheritance: A Rigorous Comparison
For decades, Rupert Sheldrake's morphic resonance hypothesis — that organisms inherit form and behavior through a non-material "morphic field" carrying patterns from past similar systems — has been the most prominent fri
G_2_09 — Network Analysis in Archaeology — Trade, Communication, Influence
Network analysis — rooted in graph theory and social network analysis (SNA) — provides formal mathematical tools for modeling and analyzing the structure of relationships between archaeological entities: sites, regions,
G_2_05 — Graph Theory and Knowledge Network Analysis
Graph theory — the mathematical study of networks of nodes (vertices) connected by edges (links) — provides a rigorous framework for analyzing the structure of connections in systems ranging from ancient social hierarchi
G_2_01 — Network Science and Complex Systems Applied to Ancient Trade
Network science—the mathematical study of complex interconnected systems—has emerged as a powerful tool for understanding ancient trade, cultural transmission, and civilizational collapse. By modeling ancient trade route
T_5_08 — The Psychology of Awe and Wonder: Vastness, Self-Diminishment, and Transformative Experience
Awe — the emotion arising from encounters with vast, powerful, or complex phenomena that exceed one's current mental frameworks and demand cognitive accommodation (schema revision) — has emerged since the early 2000s as
B_2_16 — Dwarf and Gnome Traditions: Norse Dvergar, Knockers, Menehune
Dwarves, gnomes, and analogous "small people" of the underground — beings associated with mining, metalwork, hidden knowledge, and subterranean realms — constitute a remarkably consistent entity category across European,
B_1_26 — Plague Deities: Disease Gods and Epidemic Mythology
Plague deities — gods and spirits who send, embody, or control epidemic disease — appear across cultures as humanity's theological response to one of its oldest and most terrifying enemies: mass contagion. Unlike natural
ZD_4_06 — Mathematical Sociology and Network Analysis
Mathematical sociology applies formal mathematical models — graph theory, probability, game theory, dynamical systems, and statistical mechanics — to understand social structures, collective behavior, and institutional d
L_1_13 — Homo Naledi: Underground Burial and Primitive Morphology
Homo naledi is one of the most unexpected and controversial hominin discoveries of the 21st century. Announced in 2015 by Lee Berger (University of the Witwatersrand) and an international team, the species was recovered
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