RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
25 results for "transplant rejection" — page 1 of 2
X_3_07 — Organ Transplantation
Organ transplantation — the surgical transfer of an organ from one body (donor) to another (recipient) — is one of the most remarkable achievements of modern medicine, transforming previously fatal organ failure into a t
S_2_13 — Xenotransplantation: Cross-Species Organs and Bioengineered Tissues
Xenotransplantation — the transplantation of organs, tissues, or cells from one species to another — is being pursued as a solution to the critical global organ shortage. In the US alone, over 100,000 people await organ
X_3_22 — Nephrology: Kidney Disease, Dialysis, and Transplantation History
Nephrology — the branch of internal medicine devoted to kidney physiology and disease — emerged as a distinct specialty in the mid-20th century, though understanding of kidney disease stretches back millennia. The kidney
Z_2_11 — Genetics of Immunity and MHC Diversity
The major histocompatibility complex (MHC) — known as the human leukocyte antigen (HLA) system in humans — is the most polymorphic gene region in the human genome, encoding cell-surface glycoproteins essential for adapti
L_3_09 — HLA Diversity and Immune System Evolution
The Human Leukocyte Antigen (HLA) system — the human version of the Major Histocompatibility Complex (MHC) found in all jawed vertebrates — is the most polymorphic gene region in the entire human genome. Located on chrom
X_2_15 — Regenerative Medicine and Stem Cell Therapy
Regenerative medicine — defined as "the process of replacing, engineering, or regenerating human or animal cells, tissues, or organs to restore or establish normal function" — is among the most rapidly advancing frontier
X_2_07 — Gut Microbiome and Digestive Health
The gut microbiome — the community of trillions of microorganisms (bacteria, archaea, fungi, viruses) inhabiting the human gastrointestinal tract — has emerged as one of the most transformative areas of biomedical resear
X_5_17 — Gastroenterology and Microbiome Medicine
Gastroenterology — the study of the gastrointestinal (GI) tract and its diseases — has been revolutionized by two discoveries: the role of Helicobacter pylori in peptic ulcer disease (Barry Marshall and Robin Warren, 198
X_3_10 — Ophthalmology and Vision Science
Ophthalmology — the medical and surgical treatment of eye diseases — and vision science — the study of how vision works — have intertwined histories spanning millennia. Ancient: eye diseases are among the most frequently
X_3_01 — Surgical History: From Trepanation to Robotics
Surgery — the physical opening and manipulation of the body to treat disease, injury, or deformity — has one of the longest and most dramatic histories in medicine. Prehistory: trepanation (trephination) — cutting or bor
X_3_13 — Microsurgery and Modern Surgical Innovation
Microsurgery — surgery performed under magnification (operating microscope or loupes) with specialized instruments on structures smaller than can be effectively manipulated by the naked eye — and the broader field of mod
X_3_24 — Gastroenterology: Microbiome Therapeutics, IBD & Gut-Brain Axis
Gastroenterology — the study and treatment of the digestive system — has undergone a revolution driven by three transformative discoveries: the bacterial etiology of peptic ulcers, the gut microbiome's role in systemic h
W_2_06 — Sikh Tradition — Guru Nanak, Adi Granth, and Universal Brotherhood
Sikhism, founded by Guru Nanak (1469–1539 CE) in the Punjab region, is the youngest of the world's major religions and among the most radical in its rejection of caste hierarchy, gender inequality, and empty ritual. Its
ZF_4_11 — Sea Ice Dynamics and Polar Oceanography
Sea ice — frozen seawater that forms a thin crust (typically 1–4 m thick) over polar and subpolar oceans — is one of Earth's most dynamic and climate-sensitive features, playing a disproportionate role in global climate
Z_5_18 — Gut-Brain Axis: The Microbiome-Nervous System Connection
The gut-brain axis — the bidirectional communication network between the gastrointestinal tract and the central nervous system — has emerged as one of the most transformative concepts in modern biology and medicine. The
Z_5_11 — Microbiome-Host Coevolution: Holobiont Theory, Gut Ecology, and Metabolic Symbiosis
Microbiome-host coevolution refers to the deep, reciprocal evolutionary relationship between multicellular organisms and the complex microbial communities (bacteria, archaea, fungi, viruses) that inhabit their bodies — p
Z_2_01 — HLA System & Archaic Immune Inheritance
The Human Leukocyte Antigen (HLA) system is the most polymorphic region of the human genome, encoding cell-surface proteins critical to adaptive immune function. Located on chromosome 6p21.3, the Major Histocompatibility
ZB_2_20 — Human Microbiome & Dysbiosis
The human microbiome — the collective genome of the ~38 trillion microorganisms (bacteria, archaea, fungi, viruses) inhabiting the human body — represents a second genome interacting with host physiology in ways that are
ZB_5_03 — Microbiome Ecology
The microbiome — the collective genomes of the trillions of microorganisms (bacteria, archaea, fungi, viruses) inhabiting a host organism or environment — has emerged as one of the most transformative research areas in 2
ZB_5_27 — Human Microbiome: Gut-Brain Axis and Microbial Ecology
The human body hosts approximately 38 trillion microbial cells — roughly equal to the number of human cells — comprising ~3,000 species of bacteria, archaea, fungi, and viruses, collectively termed the microbiome. The Hu
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