RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
102 results for "psychedelic pharmacology" — page 1 of 6
Z_4_06 — Psychedelic Neurochemistry: 5-HT2A, Tryptamines, and Molecular Mechanisms
Psychedelic neurochemistry — the molecular-level study of how psychedelic compounds alter brain function to produce their characteristic effects (visual hallucinations, synesthesia, ego dissolution, mystical-type experie
Y_1_07 — Ego Dissolution and Psychedelic Neuroscience
Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p
Y_5_20 — MDMA Pharmacology: Entactogen Mechanisms, Therapeutic Potential, and Risks
MDMA (3,4-methylenedioxymethamphetamine), commonly known as ecstasy or molly, is a synthetic entactogen (from Latin tactus, "touching within") that produces profound feelings of emotional closeness, empathy, trust, and w
Y_1_15 — Micro-Dosing: Sub-Perceptual Psychedelic Use and Cognitive Effects
Micro-dosing — the practice of regularly consuming sub-perceptual doses (typically 1/10th to 1/20th of a standard recreational dose) of psychedelic substances, most commonly LSD (~10–20 micrograms) or psilocybin (~0.1–0.
X_2_03 — Psychedelic Medicine: Clinical Evidence and Renaissance
The psychedelic renaissance — the resurgence of clinical research into psychedelic compounds after decades of prohibition — represents one of the most significant paradigm shifts in modern psychiatry. Psilocybin for trea
X_2_11 — Ethnobotanical Pharmacology: Plant-Based Medicines Across Cultures
Ethnobotanical pharmacology (or ethnopharmacology) investigates the medicinal use of plants across human cultures — encompassing the traditional knowledge systems that identified, prepared, and administered plant-based m
X_5_09 — Pharmacology: The Science of Drugs and Their Actions
Pharmacology — the science of drugs — investigates how chemical substances interact with biological systems to produce therapeutic, toxic, or other effects. The discipline encompasses pharmacokinetics (what the body does
ZF_4_05 — Marine Pharmacology and Drug Discovery
Marine pharmacology explores the ocean's vast biodiversity as a source of bioactive compounds for drug development — a field that has yielded several approved drugs and thousands of promising leads since the pioneering w
K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects
The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica
INTERDOC_62 — Chemical Language Systems: Information Encoding from Microbes to Consciousness
Bacterial quorum sensing molecules encode population-density commands with combinatorial logic-gate precision (Bassler and Losick, 2006); microbial short-chain fatty acids (SCFAs) direct host immune programming, epigenet
INTERDOC_20 — Psychedelic Neuroscience and Ancient Ritual Practice
[KEY FINDING] The Johns Hopkins Center for Psychedelic and Consciousness Research, the Imperial College Centre for Psychedelic Research (est. 2019, directed by Robin Carhart-Harris), and the MAPS (Multidisciplinary Assoc
Y_1_04 — Psychedelic Renaissance — Clinical Research and Consciousness
The psychedelic renaissance — a resurgence of rigorous scientific research on psychedelic substances after decades of prohibition — has produced some of the most significant findings in 21st-century psychiatry and consci
Y_1_02 — Ergot, Sacred Pharmacology, and History
This document examines Ergot, Sacred Pharmacology, and History, a topic within the Consciousness research area. Key areas of investigation include Claviceps purpurea — Biology and Chemistry, Ergot Alkaloids — The Chemist
Y_1_06 — Psychedelic Research — Modern Science and Ancient Entheogen Parallels
Psychedelic research has undergone a dramatic revival since ~2006, with major studies at Johns Hopkins, Imperial College London, NYU, and MAPS demonstrating the therapeutic potential of psilocybin, MDMA, and ayahuasca/DM
Y_1_16 — Psychedelic Legal Frameworks: Regulation, Decriminalization, and Therapeutic Access
The legal status of psychedelic substances — including psilocybin, LSD, MDMA, DMT/ayahuasca, mescaline, and ibogaine — has undergone dramatic shifts since the mid-20th century, moving from unregulated research compounds
Y_1_01 — Altered States, Psychedelics & Ancient Knowledge
Psychoactive substances played a significant — possibly central — role in ancient knowledge traditions. The Eleusinian Mysteries (kykeon), Vedic tradition (Soma), Egyptian practice (blue lotus), and Mesoamerican religion
H_4_06 — Suppression of Psychedelic Research (1960s–2000s)
From the late 1940s through the mid-1960s, psychedelic substances — particularly LSD (lysergic acid diethylamide) and psilocybin — were the subject of extensive legitimate scientific research, with over 1,000 peer-review
ZE_3_06 — Ethics of Psychedelic Research and Therapy
The ethics of psychedelic research and therapy addresses the unique moral challenges posed by substances that profoundly alter consciousness in therapeutic, religious, and research contexts. After a 40-year research mora
X_5_26 — Psychedelic Medicine: The Johns Hopkins Center and the Therapeutic Renaissance
The psychedelic therapy renaissance — centered at the Johns Hopkins Center for Psychedelic and Consciousness Research (established 2019, originally launched as a research program in 2000) — represents one of the most sig
INTERDOC_72 — The Psychedelic Entropy Paradox: Coherence Through Anarchy
The "Entropic Brain" hypothesis, pioneered by Robin Carhart-Harris (Imperial College London), demonstrates that under the influence of classic psychedelics (psilocybin, LSD, DMT), the brain's Default Mode Network (DMN) d
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