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24 results for "psilocybin" — page 1 of 2
K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects
The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica
R_2_07 — Stoned Ape Hypothesis — Psilocybin, Cognitive Evolution, and the McKenna Theory
The "Stoned Ape Hypothesis," proposed by ethnobotanist Terence McKenna in Food of the Gods (1992), posits that the consumption of psilocybin-containing mushrooms by early hominids (particularly Homo erectus and Homo erga
X_2_03 — Psychedelic Medicine: Clinical Evidence and Renaissance
The psychedelic renaissance — the resurgence of clinical research into psychedelic compounds after decades of prohibition — represents one of the most significant paradigm shifts in modern psychiatry. Psilocybin for trea
X_5_26 — Psychedelic Medicine: The Johns Hopkins Center and the Therapeutic Renaissance
The psychedelic therapy renaissance — centered at the Johns Hopkins Center for Psychedelic and Consciousness Research (established 2019, originally launched as a research program in 2000) — represents one of the most sig
Z_4_06 — Psychedelic Neurochemistry: 5-HT2A, Tryptamines, and Molecular Mechanisms
Psychedelic neurochemistry — the molecular-level study of how psychedelic compounds alter brain function to produce their characteristic effects (visual hallucinations, synesthesia, ego dissolution, mystical-type experie
K_1_04 — Brain as Filter vs Generator
Two opposing models have dominated the consciousness debate for over a century:
K_4_01 — Shamanism, Entheogens & Serpent Visions
Shamanism as a cross-cultural altered-state practice is Tier 1 anthropology (Eliade 1964, Winkelman 2010). Clinical psilocybin and DMT research is Tier 1 (Griffiths 2006/2019, Strassman 2001, Davis 2021). The consistent
INTERDOC_20 — Psychedelic Neuroscience and Ancient Ritual Practice
[KEY FINDING] The Johns Hopkins Center for Psychedelic and Consciousness Research, the Imperial College Centre for Psychedelic Research (est. 2019, directed by Robin Carhart-Harris), and the MAPS (Multidisciplinary Assoc
G_3_03 — Mycelium Network
Mycorrhizal ("Wood Wide Web") nutrient-and-signal transfer between trees is Tier 1 established ecology (Simard 2021, Sheldrake 2020). Fungal computation and decision-making in organisms like Physarum polycephalum are Tie
T_5_14 — Peak Experiences and Ecstasy: Maslow, Mystical States, and Transformative Moments
Peak experiences — moments of ecstatic joy, profound meaning, ego-dissolution, and felt unity with the world — were identified by Abraham Maslow (1964) as among the most important experiences in human life: rare, spontan
Y_4_03 — Shamanic Practices / Altered States Synthesis
Shamanic practices represent humanity's oldest spiritual technology, attested across every inhabited continent from at least 30,000 BCE (Upper Paleolithic cave art) to the present day. Despite vast cultural distances — g
Y_3_04 — Mystical Experience — Neuroscience of the Numinous
Mystical experiences — characterized by unity consciousness, noetic quality, ineffability, transcendence of time and space, and deep positive affect — have been reported across every known culture and religious tradition
Y_3_20 — Enlightenment Neuroscience: Satori, Samadhi & Mystical States
Enlightenment — known as satori or kensho in Zen Buddhism, samadhi in Hindu yogic traditions, fana in Sufism, theosis in Eastern Orthodox Christianity, and unio mystica in the Western mystical tradition — refers to state
Y_1_04 — Psychedelic Renaissance — Clinical Research and Consciousness
The psychedelic renaissance — a resurgence of rigorous scientific research on psychedelic substances after decades of prohibition — has produced some of the most significant findings in 21st-century psychiatry and consci
Y_1_03 — Classical Antiquity Entheogens Synthesis
This document examines Classical Antiquity Entheogens Synthesis, a topic within the Consciousness research area. Key areas of investigation include Were Ancient Mediterranean Religions Entheogenic?, Why This Matters, The
Y_1_02 — Ergot, Sacred Pharmacology, and History
This document examines Ergot, Sacred Pharmacology, and History, a topic within the Consciousness research area. Key areas of investigation include Claviceps purpurea — Biology and Chemistry, Ergot Alkaloids — The Chemist
Y_1_06 — Psychedelic Research — Modern Science and Ancient Entheogen Parallels
Psychedelic research has undergone a dramatic revival since ~2006, with major studies at Johns Hopkins, Imperial College London, NYU, and MAPS demonstrating the therapeutic potential of psilocybin, MDMA, and ayahuasca/DM
Y_1_15 — Micro-Dosing: Sub-Perceptual Psychedelic Use and Cognitive Effects
Micro-dosing — the practice of regularly consuming sub-perceptual doses (typically 1/10th to 1/20th of a standard recreational dose) of psychedelic substances, most commonly LSD (~10–20 micrograms) or psilocybin (~0.1–0.
Y_1_07 — Ego Dissolution and Psychedelic Neuroscience
Ego dissolution — the temporary loss of the subjective sense of self, personal boundaries, and the distinction between self and world — is among the most profound and therapeutically significant effects of serotonergic p
Y_1_16 — Psychedelic Legal Frameworks: Regulation, Decriminalization, and Therapeutic Access
The legal status of psychedelic substances — including psilocybin, LSD, MDMA, DMT/ayahuasca, mescaline, and ibogaine — has undergone dramatic shifts since the mid-20th century, moving from unregulated research compounds
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