RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

54 results for "psi" — page 1 of 3

K_3_17 Verified Consciousness

K_3_17 — Psychedelic Consciousness — DMT, Psilocybin Neural Effects

The psychedelic renaissance in neuroscience — a period of renewed scientific investigation beginning circa 2006 after decades of regulatory restriction — has produced an unprecedented body of neuroimaging, pharmacologica

psychedelic psilocybin DMT dimethyltryptamine LSD 5-HT2A receptor
K_4_16 Credible Consciousness

K_4_16 — Psi Research Meta-Analysis: Parapsychology, Statistical Evidence, and the Replication Debate

Parapsychology — the scientific study of purported psychic phenomena (psi), including telepathy, clairvoyance, precognition, and psychokinesis — has accumulated over a century of experimental research with a complex and

psi parapsychology meta-analysis Ganzfeld precognition remote viewing
K_4_08 Credible Consciousness

K_4_08 — Parapsychology — Experimental Research on Psi Phenomena

Parapsychology is the scientific study of purported psychic phenomena — telepathy, clairvoyance, precognition, and psychokinesis (collectively termed "psi") — using experimental methods. Originating with J.B. Rhine's car

parapsychology psi ESP extrasensory perception Rhine Ganzfeld
R_2_07 Credible Biology & Evolution

R_2_07 — Stoned Ape Hypothesis — Psilocybin, Cognitive Evolution, and the McKenna Theory

The "Stoned Ape Hypothesis," proposed by ethnobotanist Terence McKenna in Food of the Gods (1992), posits that the consumption of psilocybin-containing mushrooms by early hominids (particularly Homo erectus and Homo erga

stoned ape hypothesis Terence McKenna psilocybin mushrooms cognitive evolution neurogenesis
X_2_03 Verified Medicine & Healing

X_2_03 — Psychedelic Medicine: Clinical Evidence and Renaissance

The psychedelic renaissance — the resurgence of clinical research into psychedelic compounds after decades of prohibition — represents one of the most significant paradigm shifts in modern psychiatry. Psilocybin for trea

psychedelic therapy psilocybin MDMA LSD ketamine DMT
X_5_26 Verified Medicine & Healing

X_5_26 — Psychedelic Medicine: The Johns Hopkins Center and the Therapeutic Renaissance

The psychedelic therapy renaissance — centered at the Johns Hopkins Center for Psychedelic and Consciousness Research (established 2019, originally launched as a research program in 2000) — represents one of the most sig

psychedelic medicine psilocybin johns hopkins MDMA therapeutic clinical trials
X_1_01 Verified Medicine & Healing

X_1_01 — History of Medicine: From Trepanation to Modern Surgery

The history of medicine spans from Neolithic trepanation (the oldest documented surgical procedure, ~7,000 BCE, with survival rates exceeding 70% in some populations) through the classical traditions of Hippocrates, Gale

history of medicine trepanation surgery anesthesia antisepsis germ theory
X_3_11 Verified Medicine & Healing

X_3_11 — Battlefield Medicine: Surgical Innovation Under Fire

Battlefield medicine — the practice of treating wounded soldiers under active combat conditions — has been one of the most powerful and paradoxical engines of medical innovation in human history. The pressure of mass cas

battlefield medicine military surgery triage trauma surgery ambulance wound care
X_3_01 Verified Medicine & Healing

X_3_01 — Surgical History: From Trepanation to Robotics

Surgery — the physical opening and manipulation of the body to treat disease, injury, or deformity — has one of the longest and most dramatic histories in medicine. Prehistory: trepanation (trephination) — cutting or bor

surgery trepanation anesthesia antisepsis Joseph Lister Ignaz Semmelweis
W_4_07 Verified World Civilizations

W_4_07 — Amazonian Traditions, Plant Teachers, and the Ayahuasca Complex

The Amazon Basin — the world's largest tropical rainforest — is home to approximately 400 indigenous groups with an extraordinary tradition of plant-based knowledge unmatched anywhere on Earth. At the center of this trad

ayahuasca DMT Banisteriopsis caapi Psychotria viridis Shipibo icaros
W_1_02 Verified World Civilizations

W_1_02 — Minoan Civilization, Bull Cult, and the Labyrinth

The Minoan civilization (c. 2700–1450 BCE) on Crete represents one of Europe's earliest complex societies — preceding Classical Greece by over a millennium. Its archaeological record reveals a sophisticated culture cente

Minoan Knossos Crete bull-leaping taurokathapsia Minotaur
ZH_5_17 Credible Archaeoastronomy

ZH_5_17 — Ancient Variable Star Observations (Algol)

Algol (Beta Persei, the "Demon Star") — a second-magnitude eclipsing binary star in the constellation Perseus that dims dramatically every 2.867 days as its fainter companion transits the primary star — may have been rec

Algol variable star eclipsing binary Beta Persei ancient observation Cairo Calendar
ZF_2_15 Credible Oceanography

ZF_2_15 — Jellyfish Ecology: Blooms, Climate Change, and Gelatinous Dominance

Jellyfish (Cnidaria: Scyphozoa, Cubozoa, Hydrozoa, and the distantly related Ctenophora) are among the oldest and most ecologically significant animals in the ocean — with a fossil record extending over 500 million years

jellyfish cnidaria scyphozoa jellyfish bloom gelatinous zooplankton Aurelia aurita
Z_3_06 Verified Molecular Biology

Z_3_06 — Genetics of Circadian Rhythms

Circadian rhythms — endogenous ~24-hour oscillations in physiology and behavior — are generated by an intracellular transcription-translation feedback loop (TTFL) encoded by a set of core clock genes conserved across ani

circadian rhythm clock genes CLOCK BMAL1 PER CRY
Z_1_09 Verified Molecular Biology

Z_1_09 — Copy Number Variation and Structural Genomics

Copy number variations (CNVs) — segments of DNA ranging from ~1 kilobase to several megabases that are present in variable numbers across individuals — represent the most impactful form of genetic variation in the human

copy number variation CNV structural variation deletion duplication inversion
Z_4_06 Verified Molecular Biology

Z_4_06 — Psychedelic Neurochemistry: 5-HT2A, Tryptamines, and Molecular Mechanisms

Psychedelic neurochemistry — the molecular-level study of how psychedelic compounds alter brain function to produce their characteristic effects (visual hallucinations, synesthesia, ego dissolution, mystical-type experie

psychedelics 5-HT2A receptor serotonin tryptamines psilocybin LSD
K_1_04 Credible Consciousness

K_1_04 — Brain as Filter vs Generator

Two opposing models have dominated the consciousness debate for over a century:

filter theory reducing valve brain as receiver brain as generator William James Aldous Huxley
K_4_10 Credible Consciousness

K_4_10 — Telepathy Research

Telepathy — direct mind-to-mind communication — appears in virtually every ancient tradition, from Vedic siddhis and Buddhist abhijñā to Aboriginal Dreamtime and Biblical prophecy. Modern experimental research includes G

telepathy remote viewing Ganzfeld Stargate psi parapsychology
K_4_01 Verified Consciousness

K_4_01 — Shamanism, Entheogens & Serpent Visions

Shamanism as a cross-cultural altered-state practice is Tier 1 anthropology (Eliade 1964, Winkelman 2010). Clinical psilocybin and DMT research is Tier 1 (Griffiths 2006/2019, Strassman 2001, Davis 2021). The consistent

shamanism DMT ayahuasca psilocybin Strassman Harner
K_2_16 Verified Consciousness

K_2_16 — Optogenetics: Light-Controlled Neural Circuits

Optogenetics is a biological technique that uses genetically encoded light-sensitive proteins (opsins) to control the activity of specific neurons with millisecond precision using light. Developed primarily by Karl Deiss

optogenetics channelrhodopsin halorhodopsin archaerhodopsin ChR2 opsins