RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

74 results for "positive selection" — page 1 of 4

L_4_09 Verified Genetics & Origins

L_4_09 — Selective Sweeps and Positive Selection in Humans

A selective sweep occurs when a beneficial allele rises rapidly in frequency under positive natural selection, carrying nearby linked variants along with it (genetic hitchhiking) and reducing genetic variation across the

selective sweep positive selection natural selection allele frequency hitchhiking extended haplotype homozygosity
Z_3_01 Verified Molecular Biology

Z_3_01 — Genetics of Brain Development — ASPM, Microcephalin, HAR1

The human brain is approximately three times larger than expected for a primate of our body size, with a vastly expanded cerebral cortex containing ~86 billion neurons. Identifying the genetic basis for this extraordinar

ASPM microcephalin MCPH1 HAR1 human accelerated regions brain evolution
T_1_16 Verified Psychology & Social

T_1_16 — Positive Psychology: The PERMA Model and Human Flourishing

Positive psychology — the scientific study of optimal human functioning, well-being, and the conditions enabling individuals and communities to flourish — was formally launched as a distinct movement by Martin Seligman d

positive psychology PERMA Seligman flourishing well-being character strengths
L_3_13 Verified Genetics & Origins

L_3_13 — Human Accelerated Regions: What Makes Us Genetically Unique

Human Accelerated Regions (HARs) are short segments of the genome that were highly conserved across millions of years of mammalian evolution — indicating strong functional constraint — but then underwent a burst of rapid

human accelerated regions HARs HAR1 HACNS1 conserved noncoding enhancer
L_3_03 Verified Genetics & Origins

L_3_03 — Lactase Persistence and Gene-Culture Coevolution

Lactase persistence — the ability of adults to digest the milk sugar lactose — is the most thoroughly documented case of gene-culture coevolution in the human species. The ancestral mammalian condition is lactase non-per

lactase persistence lactose intolerance LCT gene gene-culture coevolution pastoralism dairy farming
R_2_14 Verified Biology & Evolution

R_2_14 — Recent Human Evolution: Lactase Persistence, Altitude Adaptation, and Malaria Resistance

Human evolution did not stop with the emergence of Homo sapiens ~300,000 years ago — natural selection has continued to shape human biology in response to agriculture, diet, disease, climate, and altitude, producing some

recent human evolution lactase persistence LCT gene altitude adaptation EPAS1 HIF pathway
ZB_1_13 Verified Ecology & Biology

ZB_1_13 — Sexual Selection and Mate Choice

Sexual selection — first articulated by Darwin (1871) in The Descent of Man, and Selection in Relation to Sex — is the evolutionary process by which traits that increase mating success are favored, even when they decreas

sexual selection mate choice intersexual selection intrasexual competition peacock tail ornament
T_2_04 Verified Psychology & Social

T_2_04 — Positive Psychology & Wellbeing Science

Positive psychology — the scientific study of what makes life worth living — was formally launched by Martin Seligman in his 1998 APA presidential address, shifting psychology's traditional focus from pathology and dysfu

positive psychology Seligman flourishing PERMA flow Csikszentmihalyi
R_3_04 Verified Biology & Evolution

R_3_04 — Sexual Selection — Mate Choice and Evolutionary Aesthetics

Sexual selection, first articulated by Charles Darwin in The Descent of Man, and Selection in Relation to Sex (1871), explains traits that enhance mating success rather than survival — from the peacock's extravagant tail

sexual selection Darwin mate choice peacock's tail Fisher's runaway Zahavi handicap principle
T_2_15 Credible Psychology & Social

T_2_15 — Gratitude and Forgiveness: Prosocial Emotions, Health Benefits, and Psychological Resilience

Gratitude and forgiveness — two central topics in positive psychology — represent prosocial emotional responses that profoundly influence interpersonal relationships, mental health, and physical well-being. Gratitude — t

gratitude forgiveness prosocial emotion positive psychology Emmons McCullough
T_5_08 Credible Psychology & Social

T_5_08 — The Psychology of Awe and Wonder: Vastness, Self-Diminishment, and Transformative Experience

Awe — the emotion arising from encounters with vast, powerful, or complex phenomena that exceed one's current mental frameworks and demand cognitive accommodation (schema revision) — has emerged since the early 2000s as

awe wonder vastness self-diminishment small self Keltner
L_3_12 Verified Genetics & Origins

L_3_12 — Genetics of Pigmentation: Skin, Hair, and Eye Color Evolution

Human pigmentation — the variation in skin, hair, and eye color across populations — is one of the most visible and best-understood examples of natural selection in our species. Pigmentation is determined primarily by th

pigmentation melanin skin color SLC24A5 SLC45A2 MC1R
L_5_10 Verified Genetics & Origins

L_5_10 — Neandertal Introgression: Which Genes and Why They Persisted

When modern humans (Homo sapiens) migrated out of Africa ~60,000-70,000 years ago and encountered Neanderthals (Homo neanderthalensis) in western Asia and Europe, the two species interbred — and the genetic legacy of tha

Neandertal introgression admixture adaptive introgression purifying selection immune genes
L_5_06 Verified Genetics & Origins

L_5_06 — Genetic Adaptation to Disease: Malaria, Plague, TB

Infectious disease has been the most powerful selective force on the human genome throughout history. Pathogens — particularly malaria, plague, tuberculosis, smallpox, and cholera — have killed more humans than all other

natural selection disease adaptation malaria sickle cell G6PD Duffy antigen
H_3_16 Verified Suppression & Thesis

H_3_16 — The Classics Canon: What Was Selected, What Was Lost

Of the vast literary output of the ancient Greek and Roman world — estimated at tens of thousands of texts — only a tiny fraction survives. The ancient classics canon as we know it is not a representative sample of ancie

canon classics selection transmission manuscript library
P_2_13 Verified Philosophy & Meaning

P_2_13 — Philosophy of Biology: Teleology, Species Concepts, and Function

The philosophy of biology examines the conceptual foundations, explanatory structures, and ontological commitments of the biological sciences — asking questions that biology itself presupposes but does not typically addr

philosophy of biology species concept biological species teleology function natural selection
R_2_11 Verified Biology & Evolution

R_2_11 — Convergent Evolution: Parallel Solutions Across Lineages

Convergent evolution — the independent origin of similar features in unrelated lineages — is one of the most striking patterns in the history of life, suggesting that natural selection repeatedly discovers the same "solu

convergent evolution parallel evolution analogy homoplasy camera eye echolocation
U_4_03 Verified Art, Music & Culture

U_4_03 — Cultural Evolution — Dual Inheritance and Cumulative Culture

Cultural evolution theory applies Darwinian principles — variation, selection, inheritance — to the transmission and transformation of cultural information (beliefs, technologies, norms, institutions). The dual inheritan

cultural evolution dual inheritance gene-culture coevolution cumulative culture Boyd Richerson memetics
ZH_5_13 Verified Archaeoastronomy

ZH_5_13 — Archaeoastronomical Controversies: Precision Debates and Methodological Limits

Archaeoastronomy — the study of how past cultures understood and used celestial phenomena — has been marked by recurring methodological controversies since its modern founding in the 1960s. The central problem: when an a

archaeoastronomy controversy methodology statistical testing selection bias megalithic yard
C_2_01 Verified Global Traditions

C_2_01 — World Religions & Serpent/Reptilian Connections

Serpent and reptilian beings appear across every major world religion — Christianity, Islam, Hinduism, Buddhism, Judaism, Gnosticism, Zoroastrianism, Egyptian tradition, Chinese cosmology, Japanese mythology, Mesoamerica

serpent religion Hinduism Buddhism Christianity Islam