RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

21 results for "placebo analgesia" — page 1 of 2

Y_4_12 Verified Altered States

Y_4_12 — Psychosomatic Phenomena and the Placebo Effect

Psychosomatic phenomena — bodily changes produced by mental states — and the placebo effect — measurable physiological improvements following inert treatment — demonstrate that consciousness and belief can directly affec

placebo effect nocebo effect psychosomatic mind-body expectation conditioning
K_5_02 Verified Consciousness

K_5_02 — Pain, Consciousness, and the Nature of Suffering

Pain is one of the most philosophically revealing phenomena in consciousness studies: it is simultaneously a sensory detection system, an emotional experience, a cognitive evaluation, and a social communication — and the

pain consciousness suffering neuroscience pain matrix neuromatrix theory Melzack gate control affective pain
Credible

INTERDOC_23 — Placebo, Nocebo, and the Biology of Belief

[KEY FINDING] The placebo effect is not "fake medicine" — it involves genuine, measurable physiological changes mediated by endogenous neurotransmitter systems. Fabrizio Benedetti (University of Turin) has demonstrated:

placebo effect nocebo effect belief expectation endogenous opioids dopamine
X_2_01 Verified Medicine & Healing

X_2_01 — Psychosomatic Medicine and Placebo Science

The placebo effect — measurable physiological change resulting from the belief or expectation of treatment rather than the treatment's pharmacological action — is among the most replicated and least understood phenomena

psychosomatic medicine placebo effect nocebo psychoneuroimmunology mind-body medicine stress response
T_2_13 Verified Psychology & Social

T_2_13 — Placebo and Nocebo Effects

The placebo effect — a measurable physiological or psychological improvement in response to an inert treatment — is one of the most robust and well-documented phenomena in medicine and psychology, while the nocebo effect

placebo effect nocebo effect placebo response expectation conditioning endorphins
X_1_11 Verified Medicine & Healing

X_1_11 — Homeopathy: History and Controversy

Homeopathy — a medical system founded by German physician Samuel Hahnemann (1755–1843) based on the principle of similia similibus curentur ("like cures like") — holds that substances causing symptoms in healthy people c

homeopathy Samuel Hahnemann similia similibus curentur like cures like potentization dilution
Credible

Mind_Body_Healing_Frontier

The scientific investigation of mind-body interactions has progressed from fringe speculation to a major research domain supported by institutional infrastructure (National Center for Complementary and Integrative Health

placebo effect psychoneuroimmunology mind-body medicine meditation neuroplasticity epigenetics
X_2_05 Credible Medicine & Healing

X_2_05 — Naturopathy and Integrative Medicine

Naturopathy — a system of medical practice emphasizing the body's innate healing capacity, natural remedies, and prevention — and integrative medicine — the combination of conventional and complementary approaches based

naturopathy integrative medicine complementary medicine CAM holistic Lust
X_2_13 Verified Medicine & Healing

X_2_13 — Pain Science: Nociception, Perception, and the Biopsychosocial Model

Pain is one of the most universal human experiences — and one of the most complex phenomena in medicine and neuroscience. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory

pain nociception chronic pain gate control theory Melzack Wall
X_2_16 Verified Medicine & Healing

X_2_16 — Evidence-Based Medicine and Clinical Trials

Evidence-based medicine (EBM) — the systematic integration of the best available research evidence with clinical expertise and patient values to guide medical decision-making — was formalized as a paradigm by Gordon Guya

evidence-based-medicine randomized-controlled-trial cochrane meta-analysis systematic-review blinding
X_5_20 Verified Medicine & Healing

X_5_20 — Medical Regulation: Clinical Trials, Drug Safety, and the History of Oversight

Medical regulation — the system of laws, agencies, and protocols governing drug development, clinical trials, and medical device approval — evolved over centuries from virtually no oversight to the elaborate global frame

medical regulation clinical trials FDA EMA drug safety thalidomide
X_1_10 Verified Medicine & Healing

X_1_10 — Acupuncture and Meridian Theory

Acupuncture — the insertion of thin needles into specific points on the body to treat pain and disease — is one of the most widely practiced and scientifically studied forms of traditional medicine, yet remains among the

acupuncture meridian qi Traditional Chinese Medicine needling moxibustion
X_3_09 Verified Medicine & Healing

X_3_09 — Anesthesia and Pain Management

Anesthesia and pain management — the medical control of pain and consciousness — revolutionized surgery and transformed the human experience of medical care. Before anesthesia, surgery was an ordeal of extreme suffering

anesthesia ether chloroform pain management analgesic opioid
K_4_02 Verified Consciousness

K_4_02 — Stigmata, Faith Healing, and Psychosomatic Phenomena

The human body can do things under the influence of belief that should not be physically possible according to conventional medical models. The placebo effect — a "sugar pill" producing measurable physiological changes —

stigmata faith healing psychosomatic placebo effect nocebo spontaneous remission
K_5_20 Verified Consciousness

K_5_20 — Psychoneuroimmunology: Mind-Body-Immune Connections

Psychoneuroimmunology (PNI) — the study of interactions between psychological processes, the nervous system, and immune function — has established that the mind directly influences immune defense and that immune activity

psychoneuroimmunology PNI mind-body stress immunity cortisol cytokines
ZC_5_17 Credible Social Science

ZC_5_17 — Ritual Efficacy Mechanisms: How Ritual Produces Real-World Effects

Ritual — formalized, repetitive, symbolic action that is culturally prescribed and often marked as distinct from ordinary behavior — is a universal feature of human societies, found in religious ceremonies, civic commemo

ritual ritual efficacy performance theory Rappaport Turner liminality
ZC_4_04 Verified Social Science

ZC_4_04 — Medical Anthropology — Culture, Healing, and the Body

Medical anthropology — the study of how health, illness, healing, and the body are experienced, understood, and managed across cultures — is one of anthropology's most productive subfields, bridging biological and social

medical anthropology healing illness disease sickness culture
T_2_06 Verified Psychology & Social

T_2_06 — Health Psychology and Stress

Health psychology investigates how psychological, behavioral, and social factors influence health, illness, and healthcare — integrating biological and psychosocial perspectives within the biopsychosocial model (Engel, 1

health psychology stress psychoneuroimmunology fight-or-flight HPA axis cortisol
T_2_14 Verified Psychology & Social

T_2_14 — Hypnosis: Suggestion, Trance, and the Science of Hypnotic Phenomena

Hypnosis — a procedure involving an induction (typically relaxation and focused attention instructions) followed by suggestions for changes in perception, sensation, emotion, thought, or behavior — has oscillated between

hypnosis hypnotic suggestion trance suggestibility hypnotherapy Hilgard
Y_5_07 Verified Altered States

Y_5_07 — Phenomenology of Pain and Pain Modulation

Pain — defined by the International Association for the Study of Pain (IASP, revised 2020) as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissu

pain nociception pain modulation gate control theory Melzack Wall