RESEARCH BASE
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287 results for "non-coding RNA" — page 1 of 15
Z_1_19 — Non-Coding RNA and Gene Regulation
Non-coding RNAs (ncRNAs) — RNA molecules that are transcribed from the genome but do not encode proteins — have emerged as central regulators of gene expression, challenging the classical "one gene–one protein" paradigm
Z_4_17 — Non-coding RNA Networks: Regulation Beyond the Genome
Non-coding RNAs (ncRNAs) — RNA molecules that are not translated into protein but perform functional roles in the cell — have emerged since the late 1990s as a vast and previously unsuspected layer of biological regulati
Z_1_15 — Long Non-Coding RNA: The Dark Matter of the Transcriptome
Long non-coding RNAs (lncRNAs) — RNA transcripts longer than 200 nucleotides that do not encode proteins — represent one of the most surprising and rapidly expanding frontiers of molecular biology. The human genome encod
Z_1_21 — Riboswitches and RNA Thermometers
Riboswitches are structured RNA elements typically found in the 5' untranslated regions (5' UTRs) of bacterial messenger RNAs that directly sense and bind specific small-molecule metabolites — changing their three-dimens
Z_1_01 — ENCODE Project, Non-Coding DNA & Epigenetics
The human genome is ~3.2 billion base pairs long, but only ~1.5% encodes proteins. The remaining ~98.5% was once dismissed as "junk DNA." The ENCODE Project (2003–present) revealed that at least 80% of the genome has bio
Z_4_04 — RNA Biology: Types and Functions
RNA (ribonucleic acid) — once considered merely a passive intermediary between DNA and protein — is now recognized as the most functionally diverse class of biological macromolecules, performing roles in catalysis, gene
A_1_12 — Amarna Letters: Bronze Age International Diplomacy
The Amarna Letters are a corpus of approximately 382 cuneiform clay tablets discovered in 1887 at Tell el-Amarna in Middle Egypt — the site of Akhenaten's short-lived capital, Akhetaten. Dating to approximately 1360–1332
U_3_14 — Vernacular Architecture: Indigenous, Anti-Colonial, and Resistance Design
Vernacular architecture — buildings designed and constructed by their inhabitants or local builders using traditional techniques, local materials, and accumulated environmental knowledge, without the intervention of prof
X_3_27 — mRNA Technology Development & Revolution
The development of messenger RNA (mRNA) therapeutics represents one of the most dramatic scientific success stories of the twenty-first century — a technology decades in the making that went from academic obscurity and f
ZF_5_05 — UNCLOS and Ocean Governance: Maritime Law, EEZ, and High Seas
The United Nations Convention on the Law of the Sea (UNCLOS), adopted in 1982 and entering into force in 1994, is the comprehensive legal framework governing all uses of the world's oceans — often called the "Constitutio
Z_5_12 — Splicing: RNA Processing and Alternative Splicing
RNA splicing — the process by which intervening sequences (introns) are removed from precursor messenger RNA (pre-mRNA) and the remaining sequences (exons) are joined together to form the mature mRNA — is a fundamental s
Z_1_04 — Gene Expression and Regulation
Gene expression regulation — the molecular mechanisms controlling when, where, and how much each gene is active — is the central process that enables a single genome to produce ~200 distinct cell types, orchestrate embry
Z_1_20 — RNA World Hypothesis
The RNA World hypothesis proposes that life on Earth passed through an early stage in which RNA molecules served as both the carriers of genetic information AND the catalysts of chemical reactions — performing the dual r
Z_4_14 — RNA Interference: Gene Silencing by Small RNAs
RNA interference (RNAi) — the process by which small double-stranded RNA molecules silence gene expression by targeting complementary messenger RNA (mRNA) for degradation or translational repression — is one of the most
E_4_24 — Quaternary Science: Integrating Ice Ages, Extinctions, and Migrations
Quaternary science is the interdisciplinary study of Earth's most recent geological period — the Quaternary (2.58 Ma to present), encompassing the Pleistocene (2.58 Ma to 11,700 BP) and the Holocene (11,700 BP to present
ZG_3_03 — Phonetics and the International Phonetic Alphabet
Phonetics is the scientific study of speech sounds — how they are produced by the human vocal tract (articulatory phonetics), how they propagate as acoustic signals (acoustic phonetics), and how they are perceived by the
J_4_13 — Ancient Fire Technology: Kilns, Furnaces, and Thermal Engineering
The controlled use of fire — humanity's foundational transformative technology — evolved from the earliest campfires (evidence of controlled fire use dates to at least 1 million years ago at Wonderwerk Cave, South Africa
Q_1_17 — Modified Gravity Theories (MOND, TeVeS, and Alternatives to Dark Matter)
Modified Newtonian Dynamics (MOND) is a hypothesis proposed by Mordehai Milgrom in 1983 that modifies Newton's second law at very low accelerations (below approximately 1.2 × 10⁻¹⁰ m/s²) to explain galaxy rotation curves
Q_1_19 — Cosmic Inflation Alternatives: Bouncing, Cyclic, and Variable Speed of Light Models
Cosmic inflation — the paradigm that the universe underwent exponential expansion in the first ~10⁻³⁶ to 10⁻³² seconds — has been the standard framework for explaining the horizon problem (why the cosmic microwave backgr
ZC_3_23 — Commons Governance — Ostrom
Elinor Ostrom (1933–2012), professor of political science at Indiana University Bloomington, became the first woman to receive the Nobel Memorial Prize in Economic Sciences (2009) for her groundbreaking work demonstratin
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