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14 results for "metabolism"

Z_3_12 Molecular Biology

Z_3_12 — Genetics of Alcohol Metabolism

The genetics of alcohol metabolism provides one of the clearest examples of how specific genetic variants influence behavior and disease risk at a population scale. Ethanol is metabolized primarily through a two-step oxi

alcohol metabolism ADH1B ALDH2 acetaldehyde Asian flush alcohol dehydrogenase
Z_2_04 Molecular Biology

Z_2_04 — Genetic Disorders and Inborn Errors of Metabolism

Genetic disorders — diseases caused by mutations in single genes (monogenic) or chromosomal abnormalities — affect ~3–5% of live births and collectively represent thousands of distinct conditions catalogued in the Online

genetic disorder inborn error metabolism Mendelian disease sickle cell cystic fibrosis
Y_4_21 Credible Altered States

Y_4_21 — Fasting-Induced Altered States

Fasting-induced altered states of consciousness — visionary experiences, euphoria, time distortion, dissociation, and mystical-type experiences produced by prolonged food deprivation — represent one of humanity's oldest

fasting altered states ketosis beta-hydroxybutyrate vision quest asceticism
Z_2_13 Molecular Biology

Z_2_13 — Pharmacogenomics and Personalized Medicine

Pharmacogenomics — the study of how genetic variation influences drug response — is among the most clinically actionable applications of human genetics. Adverse drug reactions (ADRs) are the 4th–6th leading cause of deat

pharmacogenomics pharmacogenetics personalized medicine precision medicine CYP2D6 CYP2C_5_04
Z_2_03 Molecular Biology

Z_2_03 — Pharmacogenomics & Ethnobotanical Genetics

Pharmacogenomics — the study of how genetic variation affects drug response — has revealed that enzymes governing drug metabolism, particularly the cytochrome P450 (CYP) superfamily, show extraordinary population-specifi

pharmacogenomics ethnobotany CYP2D6 cytochrome P450 drug metabolism traditional medicine
Z_2_18 Verified Molecular Biology

Z_2_18 — Pharmacogenomics and Precision Medicine

Pharmacogenomics — the study of how genetic variation affects individual responses to drugs — aims to replace the "one-size-fits-all" prescribing model with genotype-guided therapy, selecting the right drug at the right

pharmacogenomics precision-medicine drug-metabolism cyp450 warfarin adverse-drug-reactions
Z_2_06 Molecular Biology

Z_2_06 — Nutrigenomics and Diet-Gene Interactions

Nutrigenomics — the study of how genetic variation influences nutritional requirements, dietary responses, and disease susceptibility — and its complement nutrigenetics (how diet influences gene expression) represent a r

nutrigenomics nutrigenetics diet-gene interaction lactase persistence alcohol metabolism folate metabolism
ZC_3_21 Credible Social Science

ZC_3_21 — Degrowth Economics

Degrowth (décroissance in French) is an intellectual and political movement that challenges the foundational assumption of modern economics: that economic growth — measured by GDP — is inherently desirable, sustainable,

degrowth décroissance post-growth ecological economics GDP critique steady-state economy
L_5_03 Verified Genetics & Origins

L_5_03 — Pharmacogenomics and Ancestral Medicine

Pharmacogenomics — the study of how genetic variation influences individual responses to drugs — bridges genetics, pharmacology, and clinical medicine. Humans carry extensive polymorphism in genes encoding drug-metaboliz

pharmacogenomics CYP2D6 CYP2C_5_04 drug metabolism personalized medicine warfarin
R_5_14 Verified Biology & Evolution

R_5_14 — Thermoregulation: Endothermy, Ectothermy, and Metabolic Evolution

Thermoregulation — the ability to maintain body temperature within functional limits — is a fundamental challenge of animal life, and the strategies organisms employ span a continuum from pure ectothermy (relying on envi

thermoregulation endothermy ectothermy homeothermy poikilothermy metabolism
X_3_26 Verified Medicine & Healing

X_3_26 — Chronobiology & Circadian Medicine

Chronobiology — the study of biological rhythms — has emerged from a niche curiosity to a Nobel Prize–winning discipline with profound implications for medicine, metabolism, and mental health. [KEY FINDING] The 2017 Nobe

chronobiology circadian rhythm suprachiasmatic nucleus clock gene CLOCK BMAL1
Z_5_11 Verified Molecular Biology

Z_5_11 — Microbiome-Host Coevolution: Holobiont Theory, Gut Ecology, and Metabolic Symbiosis

Microbiome-host coevolution refers to the deep, reciprocal evolutionary relationship between multicellular organisms and the complex microbial communities (bacteria, archaea, fungi, viruses) that inhabit their bodies — p

microbiome gut microbiota holobiont dysbiosis fecal microbiota transplant FMT
Z_4_12 Verified Molecular Biology

Z_4_12 — Autophagy: The Cell's Self-Eating Recycling System

Autophagy (from Greek auto "self" + phagein "to eat") — the process by which cells degrade and recycle their own components — is a fundamental cellular quality control and survival mechanism conserved from yeast to human

autophagy Ohsumi lysosome mTOR autophagosome protein degradation
Y_5_10 Credible Altered States

Y_5_10 — Extreme Fasting: Breatharian Claims, Autophagy, and Metabolic States

Extreme fasting — prolonged and severe caloric restriction or complete food abstinence — occupies a unique position at the intersection of contemplative/ascetic practice, metabolic science, and pseudoscientific extremism

fasting autophagy caloric restriction breatharianism inedia metabolic states