RESEARCH BASE

Search 3,721 documents across 34 fields — every claim tier-rated by evidence

3,721 Documents 34 Sections 43,625 Citations 34,852 Keywords Indexed 4 Evidence Tiers

3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.

18 results for "like cures like"

X_1_11 Verified Medicine & Healing

X_1_11 — Homeopathy: History and Controversy

Homeopathy — a medical system founded by German physician Samuel Hahnemann (1755–1843) based on the principle of similia similibus curentur ("like cures like") — holds that substances causing symptoms in healthy people c

homeopathy Samuel Hahnemann similia similibus curentur like cures like potentization dilution
Z_2_08 Verified Molecular Biology

Z_2_08 — Prion Genetics and Misfolded Proteins

Prions are infectious agents composed entirely of misfolded protein — the only known pathogen that contains no nucleic acid (no DNA, no RNA). The protein-only hypothesis (Stanley Prusiner, 1982 — Nobel Prize 1997) states

prion PRNP PrP PrPSc PrPC prion diseases
Z_2_11 Verified Molecular Biology

Z_2_11 — Genetics of Immunity and MHC Diversity

The major histocompatibility complex (MHC) — known as the human leukocyte antigen (HLA) system in humans — is the most polymorphic gene region in the human genome, encoding cell-surface glycoproteins essential for adapti

major histocompatibility complex MHC HLA human leukocyte antigen adaptive immunity antigen presentation
Z_2_23 Verified Molecular Biology

Z_2_23 — Immune System & Immunology

The immune system is a multi-layered defense network that protects organisms against pathogens including bacteria, viruses, fungi, and parasites. It comprises two interconnected arms: innate immunity, which provides rapi

immune system innate immunity adaptive immunity T cells B cells antibodies
Z_4_23 Verified Molecular Biology

Z_4_23 — Memory as Physical and Molecular Phenomenon

What is a memory made of? The question has driven neuroscience from Santiago Ramón y Cajal's 1894 hypothesis that learning strengthens connections between neurons, through Donald Hebb's 1949 postulate that "neurons that

molecular memory memory engram synaptic plasticity long-term potentiation LTP Eric Kandel
Z_4_16 Verified Molecular Biology

Z_4_16 — Phase Separation in Cell Biology: Membraneless Organelles and Biomolecular Condensates

Liquid-liquid phase separation (LLPS) is the biophysical process by which proteins and nucleic acids demix from the surrounding cytoplasm or nucleoplasm to form concentrated, membrane-free droplets called biomolecular co

phase separation biomolecular condensate membraneless organelle liquid-liquid phase separation LLPS intrinsically disordered protein
K_1_09 Credible Consciousness

K_1_09 — Philosophical Zombies and the Hard Problem

The philosophical zombie (p-zombie) thought experiment, formalized by David Chalmers (1996), asks: Could there exist a being physically and functionally identical to a conscious human — identical atom for atom, processin

philosophical zombie p-zombie hard problem of consciousness David Chalmers explanatory gap qualia
K_1_14 Credible Consciousness

K_1_14 — Qualia: The Subjective Experience Problem

Qualia (singular: quale) — the term used in philosophy of mind for the subjective, experiential properties of conscious mental states — the redness of red, the painfulness of pain, the taste of coffee, the felt quality o

qualia subjective experience hard problem phenomenal consciousness Mary's Room what-it-is-like
ZB_2_06 Verified Ecology & Biology

ZB_2_06 — Immune System Evolution: From Innate to Adaptive Defense

The immune system represents one of evolution's most complex adaptive innovations — a multi-layered defense system that distinguishes self from non-self and remembers past encounters. All multicellular organisms possess

immune system innate immunity adaptive immunity T cell B cell antibody
G_2_16 Credible Modern Frameworks

G_2_16 — Phylogenetic Methods in Material Culture Analysis

Phylogenetic methods — originally developed in evolutionary biology to reconstruct the branching history of species from shared inherited characteristics — have been adapted for analyzing the evolutionary (descent-with-m

phylogenetics cladistics cultural phylogeny material culture tree branching
G_2_03 Verified Modern Frameworks

G_2_03 — Bayesian Reasoning and Archaeological Inference

Bayesian reasoning — the systematic updating of probabilities for hypotheses as new evidence is acquired — has transformed archaeology, chronology, and the evaluation of disputed historical claims since the 1990s. At its

Bayesian inference Bayes theorem prior probability posterior likelihood radiocarbon calibration
ZD_1_12 Verified Information & Computation

ZD_1_12 — Information Geometry and Fisher Information

Information geometry is the mathematical field that applies differential geometry — the mathematics of curved spaces, manifolds, metrics, and connections — to the study of probability distributions and statistical models

information geometry Fisher information statistical manifold Riemannian geometry metric tensor natural gradient
Y_4_15 Credible Altered States

Y_4_15 — Sensory Overload and Information Flooding: Excess as Altered State

Sensory overload — the state that arises when sensory input exceeds the brain's capacity for orderly processing — represents the mirror image of sensory deprivation as a pathway to altered consciousness. While deprivatio

sensory overload information overload Ganzfeld rave culture overwhelm information flooding
R_3_09 Verified Biology & Evolution

R_3_09 — Molecular Phylogenetics and Tree of Life

Molecular phylogenetics — reconstructing evolutionary relationships from DNA, RNA, and protein sequences — has revolutionized our understanding of the tree of life since Carl Woese's landmark 1977 discovery, using small-

phylogenetics molecular clock tree of life cladistics maximum likelihood Bayesian
R_3_13 Verified Biology & Evolution

R_3_13 — Evolution of the Immune System

The immune system is one of evolution's most elaborate and costly creations — vertebrate adaptive immunity alone employs V(D)J recombination to generate over 10¹¹ distinct antibody specificities from fewer than 400 gene

immune system innate immunity adaptive immunity immunoglobulin T cell B cell
ZA_2_10 Credible Physics & Quantum

ZA_2_10 — Tachyons and Superluminal Physics

Tachyons — hypothetical particles that always travel faster than light — have fascinated physicists since Gerald Feinberg's 1967 formalization, yet no tachyon has ever been observed. In special relativity, a massive part

tachyon superluminal faster than light FTL special relativity light speed barrier
ZA_2_09 Credible Physics & Quantum

ZA_2_09 — Wormholes and Exotic Spacetime Geometries

Wormholes — hypothetical tunnels through spacetime connecting distant regions of the universe or even different universes — are exact solutions of Einstein's field equations. First identified by Einstein and Rosen (1935)

wormhole Einstein-Rosen bridge traversable wormhole Morris-Thorne exotic matter negative energy
V_4_25 Verified Mathematics & Information

V_4_25 — Bayesian Inference: Probability as Rational Belief Updating

Bayesian inference — the mathematical framework for updating beliefs in light of evidence using Bayes' theorem — has become one of the most powerful and contested ideas in modern science. Named after Reverend Thomas Baye

bayesian inference bayes theorem prior probability posterior probability likelihood bayesian statistics