RESEARCH BASE
Search 3,721 documents across 34 fields — every claim tier-rated by evidence
3,633 are the core, quality-scored corpus (34 lettered sections — see How We Work); the remaining 88 are cross-corpus synthesis documents (68 InterDocs, 12 Connections, 8 Theories) also indexed here.
1,269 results for "hemolytic disease of newborn" — page 1 of 64
L_3_05 — Blood Type Genetics and the ABO System
Blood group genetics represents one of the earliest and most clinically important applications of Mendelian inheritance in human biology. Karl Landsteiner's discovery of the ABO blood group system (1900–1901) — which ear
X_5_03 — Medical Genetics and Rare Diseases
Medical genetics is the branch of medicine concerned with the diagnosis, management, and counseling of individuals and families affected by genetic disorders — conditions caused by mutations in DNA, ranging from single-g
Z_2_15 — Future of Genomics and Personalized Medicine
Genomics is undergoing a transition from research tool to clinical infrastructure. The cost of whole-genome sequencing (WGS) has plummeted from $2.7 billion (Human Genome Project, 1990–2003) to ~$200 per genome (Illumina
Z_2_04 — Genetic Disorders and Inborn Errors of Metabolism
Genetic disorders — diseases caused by mutations in single genes (monogenic) or chromosomal abnormalities — affect ~3–5% of live births and collectively represent thousands of distinct conditions catalogued in the Online
X_5_29 — Epidemiology and Pandemics: Disease, Civilization, and the Biology of Outbreaks
Epidemiology — the study of disease distribution and determinants in populations — has fundamentally shaped human history, often more decisively than warfare or politics. The Antonine Plague (165–180 CE, likely smallpox)
X_1_14 — Medical Archaeology
Medical archaeology (also called paleopathology and bioarchaeology) is the study of disease, injury, healing, and medical practice in past populations using physical evidence — primarily skeletal remains, mummified tissu
Z_2_07 — Genetics of Disease Resistance
Infectious disease has been the most powerful selective force shaping the human genome, leaving signatures across thousands of loci. The best-understood example is sickle cell disease (HbS, Glu6Val in HBB): heterozygous
B_5_06 — Deification of Natural Phenomena: Thunder, Earthquakes, Disease as Entities
Across virtually every documented human culture, natural phenomena — storms, earthquakes, volcanic eruptions, epidemics, drought — have been personified as intentional agents: gods, demons, or spirits with desires, emoti
M_3_12 — Stone Softening Claims: Mythological and Chemical Analysis
Among the most intriguing and elusive claims in alternative archaeology is the idea that ancient Andean peoples possessed a botanical or chemical method of "softening" stone — reducing hard stone (particularly the andesi
U_5_11 — Censorship in Art: Suppression of Creative Expression Through History
Censorship of art — the suppression, alteration, or prohibition of creative works by political, religious, or social authorities — is as old as civilization itself and has taken forms from the destruction of physical obj
U_4_15 — Ritual Objects and Votive Offerings: Material Culture of Devotion
Ritual objects — material things created, consecrated, or used in religious or ceremonial practice — and votive offerings — objects dedicated to a deity, saint, or supernatural power in fulfillment of a vow, in supplicat
X_5_23 — Zoonotic Disease: Pathogen Spillover from Animals to Humans
Zoonotic diseases — infections that transmit from animals to humans — constitute approximately 60–75% of all emerging infectious diseases and have caused the most devastating pandemics in human history. The Neolithic rev
X_5_15 — Paleopathology: Disease in Antiquity
Paleopathology — the study of disease in ancient human and animal remains — provides direct evidence of health, nutrition, and disease in past populations, bridging archaeology and medicine. Marc Armand Ruffer (Cairo Sch
X_1_01 — History of Medicine: From Trepanation to Modern Surgery
The history of medicine spans from Neolithic trepanation (the oldest documented surgical procedure, ~7,000 BCE, with survival rates exceeding 70% in some populations) through the classical traditions of Hippocrates, Gale
X_4_12 — Tropical Medicine: Disease, Ecology, and Global Health in the Tropics
Tropical medicine is the branch of medicine concerned with diseases that are prevalent or unique to tropical and subtropical regions — particularly vector-borne diseases (malaria, dengue, yellow fever, Chagas disease, le
X_4_14 — Global Health: Equity, Systems, and Planetary Well-Being
Global health is the field concerned with improving health and achieving health equity for all people worldwide — transcending national boundaries and addressing the determinants of health at population, environmental, a
X_4_20 — Autoimmune Disease Rise & Hygiene Hypothesis
The dramatic rise of autoimmune and allergic diseases in industrialized nations over the past half-century — while these conditions remain comparatively rare in developing countries — represents one of the most important
X_4_13 — Palliative Care and Hospice: Medicine at the End of Life
Palliative care — specialized medical care focused on providing relief from the symptoms, pain, and stress of serious illness, with the goal of improving quality of life for both the patient and the family — and hospice
X_3_20 — Infectious Disease & Epidemiology
Infectious diseases have shaped human history more profoundly than any other biological force. The germ theory of disease, established by Louis Pasteur and Robert Koch in the 1860s–1880s, transformed medicine from specul
X_3_22 — Nephrology: Kidney Disease, Dialysis, and Transplantation History
Nephrology — the branch of internal medicine devoted to kidney physiology and disease — emerged as a distinct specialty in the mid-20th century, though understanding of kidney disease stretches back millennia. The kidney
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